Protein Alignment bi and Tbx4

DIOPT Version :10

• Sequence 1: NP_001259238.1
• Gene: bi / 31379
• FlyBaseID: FBgn0000179
• Length: 1023
• Species: Drosophila melanogaster
• Sequence 2: XP_006247098.1
• Gene: Tbx4 / 303399
• RGDID: 1309057
• Length: 555
• Species: Rattus norvegicus
• Alignment Length: 560
• Identity: 191/560 - (34%)
• Similarity: 250/560 - (44%)
• Gaps: 159/560 - (28%)

  Fly   247 PAAALAALAGS-------PAGPHPGLYPGGGLRFPPHHPGAHPHAHHLGSAYTTAEDVVLASAVA 304
            |..||...:.|       ||...||| .|..|..||            |.....|.....|:|.|
  Rat    17 PGPALGETSNSNNTNVPEPALATPGL-SGTALSSPP------------GQGADVAAAAAAAAAAA 68

  Fly   305 HQLHPAMRPLRALQPEDDGVVDDPKVTLEGKDLWEKFHKLGTEMVITKSGRQMFPQMKFRVSGLD 369
            .|                 .:::.||.|..|:||:|||:.||||:|||:||:|||..|.:|:|::
  Rat    69 EQ-----------------TIENIKVGLHEKELWKKFHEAGTEMIITKAGRRMFPSYKVKVTGMN 116

  Fly   370 AKAKYILLLDIVAADDYRYKFHNSRWMVAGKADPEMPKRMYIHPDSPTTGEQWMQKVVSFHKLKL 434
            .|.|||||:|||.|||:||||.:::|||||||:|.||.|:|:|||||.||..||:::|||.||||
  Rat   117 PKTKYILLIDIVPADDHRYKFCDNKWMVAGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKL 181

  Fly   435 TNNISDKHGFVSTTILNSMHKYQPRFHLVRA--NDILKLPYSTFRTYVFKETEFIAVTAYQNEKI 497
            |||..|..|.:   |||||||||||.|:|:|  |:......:.|.|:||.||.||:||:|||.||
  Rat   182 TNNHLDPFGHI---ILNSMHKYQPRLHIVKADENNAFGSKNTAFCTHVFPETSFISVTSYQNHKI 243

  Fly   498 TQLKIDNNPFAKGFRDTGAGKREKKQALMSNRGSDSDKLNPTHVSSSRAP----------LHLGH 552
            |||||:||||||||                 ||||...|....:.|...|          |....
  Rat   244 TQLKIENNPFAKGF-----------------RGSDDSDLRVARLQSKEYPVISKSIMRQRLVSSQ 291

  Fly   553 AGRPPHLHP----HAALLDNQQDDDDKLLDVVGPPQSPLLPLSHSLQQMHAHQHSAALAAWFNHL 613
            ....|.:.|    |.||...|.::...:......||.  |||:     ....|..::|   |.|.
  Rat   292 LSAKPDVSPLHSTHQALQHYQYENGAHMQFAAAEPQD--LPLN-----TFPTQRDSSL---FYHC 346

  Fly   614 AGAGAGASEHAAAAAANASAEDALRRRLQADADVERDG-------------SDSSCSESVGGSTG 665
            ....|.::.|......        |..|:..:.|..|.             |.|.|||.
  Rat   347 LKRRADSARHLDLPCK--------RSYLETPSSVGDDHYFRSPPPYDQQMLSPSYCSEV------ 397

  Fly   666 GAFRPTSTGSPKEA-VGAAAAAAAAGLNPGGGSYPSP---NI--SVGP------------PIHPS 712
                     :|:|| :.:::....||::......|.|   |:  ||.|            |..|.
  Rat   398 ---------TPREACMYSSSGPEIAGVSAVDDLPPPPLSCNMWTSVSPYTSYSVQTMETVPYQPF 453

  Fly   713 P-H-----LLPYLYPHGLYPPPHLGLLHNPAAAAAMSPAG 746
            | |     ::|.|                |.||.:..|.|
  Rat   454 PTHFTATTMMPRL----------------PIAAQSAQPPG 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bi	NP_001259238.1	Optomotor-blind	<260..318	CDD:337907	13/57 (23%)
		T-box_TBX2_3-like	326..513	CDD:410314	116/188 (62%)
Tbx4	XP_006247098.1	T-box_TBX4_5-like	75..259	CDD:410315	116/203 (57%)