DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bi and tbx-35

DIOPT Version :9

Sequence 1:	NP_001259238.1	Gene:	bi / 31379	FlyBaseID:	FBgn0000179	Length:	1023	Species:	Drosophila melanogaster
Sequence 2:	NP_495059.2	Gene:	tbx-35 / 191239	WormBaseID:	WBGene00006554	Length:	325	Species:	Caenorhabditis elegans

Alignment Length:	202	Identity:	54/202 - (26%)
Similarity:	89/202 - (44%)	Gaps:	18/202 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   332 LEGKDLWEKFHKLGTEMVITKSGRQMFPQMKFRVSGLDAKAKYILLLDIVAADDYRYKFH--NSR 394
            |...|:::.||....|.|:....|..||...|.|..|::...|.:.|.....::.|::|:  ..:
Worm    27 LHNSDVFQLFHPDIMEQVVVNKERVFFPTPSFNVLNLESDCLYKMSLRFDKTNNKRFQFNRQTKQ 91

  Fly   395 WMVAGKADPEMPKRMYIHPDSPTTGEQWMQKVVSFHKLKLTNNISDKHGFVSTTILNSMHKYQPR 459
            |....|........:::||....||:.||:..|.|. :|:||..|.:...|  ..|.|..||||.
Worm    92 WTEYDKVSNHKESEVFVHPSEIRTGDDWMKSPVEFF-IKVTNLRSSESDEV--ICLESQCKYQPT 153

  Fly   460 FHLVRANDILKLPYSTFRTY------VFKETEFIAVTAYQNEKITQLKIDNNPFAKGFRDTGAGK 518
            ..:.:   :.:..:..|:.:      .|....|||.|.|.:.:|..:|...|||:.  :||  .|
Worm   154 LLIQK---VFRDCFGCFQAHGPPVEIKFALLTFIATTRYCSRRIADIKSSLNPFSS--QDT--KK 211

  Fly   519 REKKQAL 525
            :.|:..|
Worm   212 KNKRNTL 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bi	NP_001259238.1	Optomotor-blind	<260..318	CDD:287988
bi	NP_001259238.1	T-box	330..513	CDD:279278	49/188 (26%)
tbx-35	NP_495059.2	TBOX	23..215	CDD:214656	52/197 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810