DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bi and tbx-40

DIOPT Version :9

Sequence 1:	NP_001259238.1	Gene:	bi / 31379	FlyBaseID:	FBgn0000179	Length:	1023	Species:	Drosophila melanogaster
Sequence 2:	NP_502852.1	Gene:	tbx-40 / 190679	WormBaseID:	WBGene00006559	Length:	380	Species:	Caenorhabditis elegans

Alignment Length:	341	Identity:	81/341 - (23%)
Similarity:	133/341 - (39%)	Gaps:	87/341 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   330 VTLEGKDLWEKFHKLGTEMVITKSG-RQMFPQMKFRVSGLDAKAKYILLLDIVAADDYRYKFHNS 393
            |.:..:|.|...:. ..||::...| :.:||::.|.::||:.|::|::||.|...|:.||.|.|.
Worm     9 VQMAEEDRWLTQYP-NMEMIVNNKGPKPIFPELNFNITGLEEKSRYVVLLSIQKFDNIRYGFKNG 72

  Fly   394 RW---MVAGKADPEMPKRMYIHPDSPTTGEQWMQKVVSFHKLKLTNN--ISDKHG--FVSTTILN 451
            :|   .|......|...:.::|||....||:.|::.:.|..:::||:  ..||..  ||.|
Worm    73 KWGPSKVRHATKKEQEIKYFLHPDGTKLGEELMKETIKFDTVRITNHKKFMDKDNVFFVET---- 133

  Fly   452 SMHKYQPRFHLVRANDILKLPYSTFRTYVFKETEFIAVTAYQNEKITQLK------------IDN 504
             ||||.|...:....::....:| .|..|   .:|..||.|..|.|...|            :|.
Worm   134 -MHKYVPVLTVKNITNVESANHS-MRMEV---AQFFPVTVYNQESIGNWKSKFHKNATFENRLDG 193

  Fly   505 NPFAK--GFRDTGAGKREKKQALMS--------------NRGSDSDKLNPTHVSSSRAPLH---- 549
            ....|  ..|:..:.||.|.:..::              |..::|.:|. ..:|||   :|
Worm   194 GNKRKNTNSREEPSSKRSKNETEIAVLDILQVASQSENYNESTNSGRLQ-NEISSS---IHQFPS 254

  Fly   550 LGHAGRPPHLHP-----------HAALLDNQQDD-----DDKLL-----DVVGPP---------- 583
            ..:..:.||.:|           ..|..|.:|:.     |:.|.     |....|
Worm   255 TSYQNQYPHAYPTVNTPPIYAQQFPAPFDEKQNQFYPKTDENLAPNCAQDASSLPNFAMNQKASF 319

  Fly   584 --QSPLLPLSHSLQQM 597
              |.|..|..|...|:
Worm   320 ANQYPYHPYYHQYSQL 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bi	NP_001259238.1	Optomotor-blind	<260..318	CDD:287988
bi	NP_001259238.1	T-box	330..513	CDD:279278	55/204 (27%)
tbx-40	NP_502852.1	T-box	24..186	CDD:279278	50/170 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810