DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bi and tbx-37

DIOPT Version :9

Sequence 1:	NP_001259238.1	Gene:	bi / 31379	FlyBaseID:	FBgn0000179	Length:	1023	Species:	Drosophila melanogaster
Sequence 2:	NP_499444.2	Gene:	tbx-37 / 189977	WormBaseID:	WBGene00006556	Length:	313	Species:	Caenorhabditis elegans

Alignment Length:	308	Identity:	102/308 - (33%)
Similarity:	151/308 - (49%)	Gaps:	58/308 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   329 KVTLEGKDLWEKFHKLGTEMVIT-KSGRQMFPQMKFRVSGLDAKAKYILLLDIVAADDYRYKFHN 392
            :|:|...::||||:. .|||::| |.||.:||.:.:.|.|||..:.|.:.:.:...|..:|||..
Worm    11 EVSLNKPEIWEKFYP-KTEMIVTRKRGRVIFPHLDYNVKGLDPDSLYSIYIHLERVDGIKYKFDA 74

  Fly   393 SRWMVAGKADPEMPKRMYIHPDSPTTGEQWMQKVVSFHKLKLTNNISDKHGFVSTTILNSMHKYQ 457
            ..|..|||.||.:|.:...||....||.:||.:.|||..||:||:..:|.  ....:..|:|||.
Worm    75 GEWKEAGKGDPILPIQYKEHPRGKRTGTEWMSEPVSFAHLKITNDPENKD--QKLILAQSLHKYI 137

  Fly   458 PRFHLVRANDILKLPY-STFR------TYVFKETEFIAVTAYQNEKITQLKIDNNPFAKGFRDTG 515
            |..|:.:.:     || .||:      .:..:.|:||.|||||||::|:||:.:|.||.|||..
Worm   138 PVLHIKQLD-----PYKGTFQMDFHGVEFRLEATQFIVVTAYQNEELTKLKVHHNKFASGFRSN- 196

  Fly   516 AGKREKKQALMSNRGSDSDKLNPTHVSSSRAPLHLGHAGRPPHLHPHAALLDNQQDDDDKLLDVV 580
             |||.     :|:...:|:...|...:|:.:.|      .||.:.|.   :|..|
Worm   197 -GKRR-----LSSESENSENSPPKRSASAISSL------TPPAISPP---MDYTQ---------- 236

  Fly   581 GPPQSPLL--------PLSHSLQQMHAHQHSAALAAWFNHLAGAGAGA 620
               |:|..        |.||. .|..||   :|.|..:|:. ||..||
Worm   237 ---QNPYFFNQNFFSTPQSHQ-PQFAAH---SANAQNYNNF-GAQNGA 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bi	NP_001259238.1	Optomotor-blind	<260..318	CDD:287988
bi	NP_001259238.1	T-box	330..513	CDD:279278	73/190 (38%)
tbx-37	NP_499444.2	TBOX	9..199	CDD:238106	75/197 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810