DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bi and mls-1

DIOPT Version :9

Sequence 1:	NP_001259238.1	Gene:	bi / 31379	FlyBaseID:	FBgn0000179	Length:	1023	Species:	Drosophila melanogaster
Sequence 2:	NP_498640.1	Gene:	mls-1 / 186741	WormBaseID:	WBGene00003376	Length:	252	Species:	Caenorhabditis elegans

Alignment Length:	187	Identity:	92/187 - (49%)
Similarity:	130/187 - (69%)	Gaps:	10/187 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   329 KVTLEGKDLWEKFHKLGTEMVITKSGRQMFPQMKFRVSGLDAKAKYILLLDI--VAADDYRYKFH 391
            :|.|:..:||.:||.|||||::|||||:|||.:...::|||....|::::|:  :....:||.||
Worm    32 RVFLQSSNLWRRFHNLGTEMIVTKSGRRMFPTLSVIIAGLDPVKSYVVMVDLECIEMKRFRYSFH 96

  Fly   392 NSRWMVAGKADPEMPKRMYIHPDSPTTGEQWMQKVVSFHKLKLTNNISDKHGFVSTTILNSMHKY 456
            .|:|:..|..:.|:|.||::|.|||..|..||:..|||.|:|||||..|.:|.:   |:||||||
Worm    97 QSKWISTGPGESELPSRMFVHTDSPARGAHWMRAPVSFDKMKLTNNQLDNNGHI---IVNSMHKY 158

  Fly   457 QPRFHLVRANDILKLPYSTFRTYVFKETEFIAVTAYQNEKITQLKIDNNPFAKGFRD 513
            :||.|::..:|..|.     .|:.|:||||||||||||.:||.|||::||||||||:
Worm   159 RPRVHIIEQDDSQKR-----HTFSFEETEFIAVTAYQNHRITSLKIESNPFAKGFRE 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bi	NP_001259238.1	Optomotor-blind	<260..318	CDD:287988
bi	NP_001259238.1	T-box	330..513	CDD:279278	91/184 (49%)
mls-1	NP_498640.1	TBOX	31..212	CDD:238106	92/187 (49%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2837
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.840