DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bi and tbx-11

DIOPT Version :9

Sequence 1:	NP_001259238.1	Gene:	bi / 31379	FlyBaseID:	FBgn0000179	Length:	1023	Species:	Drosophila melanogaster
Sequence 2:	NP_498317.1	Gene:	tbx-11 / 185575	WormBaseID:	WBGene00006547	Length:	322	Species:	Caenorhabditis elegans

Alignment Length:	290	Identity:	81/290 - (27%)
Similarity:	136/290 - (46%)	Gaps:	45/290 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   325 VDDP-KVTLEG--KDLWEKFHKLGTEMVITKSGRQMFPQMKFRVSGLDAKAKYILLLDIVAADDY 386
            :|.| .|||..  ..||...|:...|||||.:||::||.:::.|:|||....|.:.:.:...||.
Worm     1 MDQPISVTLSSTTDPLWRSCHEYDNEMVITVNGRRIFPTLEYTVTGLDTFKLYSMCMHLDLVDDK 65

  Fly   387 RYKFHNSRWMVAGKADPEMPKRMYIHPDSPTTGEQWMQKVVSFHKLKLTNNISDKHGFVSTTILN 451
            :.:|...:|..:...:.:.|.|...|.:...||:.||.:.|||.::::||..|.:.|..|...|.
Worm    66 KLRFTGGQWAESVSTEKKDPPRKVWHHNGSQTGKDWMLRNVSFDQIRITNRKSKEDGNASYVHLL 130

  Fly   452 SMHKYQPRFHLVRANDIL---KLPYSTFRTYVFKETEFIAVTAYQNEKITQLKIDNNPFAKGFRD 513
            :.|:|.|...:...:.::   ::|:|          :||:||||...::..||.:|||::.|.|
Worm   131 TQHRYIPVLTIYEGDQLVHTARIPHS----------QFISVTAYHKGELNTLKTNNNPYSTGSR- 184

  Fly   514 TGAGKREKKQALMSNRGSDSDKLNPTHVSSSRAPLHLGHAGRPPHLHPHAALLDNQQDDDDKLLD 578
              ..:|.::|:.:.:.|:.|:|      |.|..|     |.:...:.|  ||.|........||.
Worm   185 --KDRRRERQSPVYSEGTSSEK------SISPPP-----AKKIKDMAP--ALPDYSVISKPNLLQ 234

  Fly   579 VV-------------GPPQSPLLPLSHSLQ 595
            .:             .||..|:.|.:..||
Worm   235 SLIFPMIAEQPSTSQSPPAPPVFPFNPDLQ 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bi	NP_001259238.1	Optomotor-blind	<260..318	CDD:287988
bi	NP_001259238.1	T-box	330..513	CDD:279278	57/187 (30%)
tbx-11	NP_498317.1	TBOX	4..189	CDD:238106	59/197 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810