DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bi and tbx-38

DIOPT Version :9

Sequence 1:	NP_001259238.1	Gene:	bi / 31379	FlyBaseID:	FBgn0000179	Length:	1023	Species:	Drosophila melanogaster
Sequence 2:	NP_499526.1	Gene:	tbx-38 / 182861	WormBaseID:	WBGene00006557	Length:	303	Species:	Caenorhabditis elegans

Alignment Length:	304	Identity:	91/304 - (29%)
Similarity:	134/304 - (44%)	Gaps:	67/304 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   329 KVTLEGKDLWEKFHKLGTEMVITKS-GRQMFPQMKFRVSGLDAKAKYILLLDIVAADDYRYKFHN 392
            ||:|...::||:|:. .|||::|:: ||.:||.:.:.:.|||..:.|.:.:.:...|..:|||..
Worm    11 KVSLSTPEIWEEFYP-KTEMIVTRNRGRVIFPHLDYIIKGLDPGSLYSIYIHLERVDGIKYKFDA 74

  Fly   393 SRWMVAGKADPEMPKRMYIHPDSPTTGEQWMQKVVSFHKLKLTNN--ISDKHGFVSTTILNSMHK 455
            ..|....|.||.:|.:...||....||.:||.:.|||..:|:|||  |.|:    ...::.||||
Worm    75 GEWKEFAKGDPILPIQYKEHPRGKRTGAEWMSEPVSFAHIKITNNPEIKDQ----KVILVQSMHK 135

  Fly   456 YQPRFHLVRANDI--LKLPY------STFRTYVFKETEFIAVTAYQNEKITQLKIDNNPFAKGFR 512
            :.|   :|....:  .|..|      ..||   .:.|||:.|||||||.:..||:.:|.||.|||
Worm   136 HIP---VVTVKQVRHYKTGYQEDFSGEQFR---LEATEFMVVTAYQNEILKNLKVHHNKFASGFR 194

  Fly   513 DTGAGKREKKQALMSNRGSDSDKLNPTHVSSSRAPLHLGHAGRPPHLHPHAALLDNQQDDDDKLL 577
            ..|      |:.|    .|||:       :|..:|........||.:.|...|
Worm   195 SNG------KRRL----SSDSE-------NSENSPPKRSKLVTPPTISPQIDL------------ 230

  Fly   578 DVVGPPQSPLL------------PLSHSLQQMHAHQHSAALAAW 609
                |.|:|..            |...|.|..:....:.|..||
Worm   231 ----PQQTPYYFNQNFVAPQNYQPQFASAQNYNFEVQNNAQLAW 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bi	NP_001259238.1	Optomotor-blind	<260..318	CDD:287988
bi	NP_001259238.1	T-box	330..513	CDD:279278	68/193 (35%)
tbx-38	NP_499526.1	TBOX	9..199	CDD:238106	71/204 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810