Protein Alignment bi and tbx-2

DIOPT Version :9

• Sequence 1: NP_001259238.1
• Gene: bi / 31379
• FlyBaseID: FBgn0000179
• Length: 1023
• Species: Drosophila melanogaster
• Sequence 2: NP_001370674.1
• Gene: tbx-2 / 175698
• WormBaseID: WBGene00006543
• Length: 423
• Species: Caenorhabditis elegans
• Alignment Length: 471
• Identity: 193/471 - (40%)
• Similarity: 244/471 - (51%)
• Gaps: 134/471 - (28%)

  Fly   205 PSTGAAAPPAGATGLPPPTPPHHLQQQQQQQQHPAPPPPPYFPAAALAALAGSPAGPHPGLYPGG 269
            |..||.....||.|                     |||..:|....    ||.|.||
 Worm    16 PFMGAGVGGPGAGG---------------------PPPNLFFSMLQ----AGFPPGP-------- 47

  Fly   270 GLRFPPHHPGAHPHAHHLGSAYTTAEDVVLASAVAHQLHPAMRPLRALQPEDDGVVDDPKVTLEG 334
                             :||                            .||||||.|||||.|:.
 Worm    48 -----------------VGS----------------------------PPEDDGVTDDPKVELDE 67

  Fly   335 KDLWEKFHKLGTEMVITKSGRQMFPQMKFRVSGLDAKAKYILLLDIVAADDYRYKFHNSRWMVAG 399
            ::||::|.:.|||||||||||::||..:.::||||.|::|.:::|:|.||::||||:|||||:||
 Worm    68 RELWQQFSQCGTEMVITKSGRRIFPAYRVKISGLDKKSQYFVMMDLVPADEHRYKFNNSRWMIAG 132

  Fly   400 KADPEMPKRMYIHPDSPTTGEQWMQKVVSFHKLKLTNNISDKHGFVSTTILNSMHKYQPRFHLVR 464
            ||||||||.:|||||||:|||.||.|..:|||||||||||||||:   ||||||||||||.|:||
 Worm   133 KADPEMPKTLYIHPDSPSTGEHWMSKGANFHKLKLTNNISDKHGY---TILNSMHKYQPRLHVVR 194

  Fly   465 ANDILKLPYSTFRTYVFKETEFIAVTAYQNEKITQLKIDNNPFAKGFRDTGAGKREKKQALMSNR 529
            ..|...|.||||||:||:||||||||||||||:|:|||:||||||||||.||||||||:.|....
 Worm   195 CADRHNLMYSTFRTFVFRETEFIAVTAYQNEKVTELKIENNPFAKGFRDAGAGKREKKRQLHRMN 259

  Fly   530 GSDSDKLNPTHVSSSRAPLHLGHAGRPPHLHPHAALLDNQQDDDDKL------------------ 576
            | |:.:..|...:|  .|.|..|...           .|.:||:..|
 Worm   260 G-DATQSPPGKTAS--LPTHSPHPSE-----------SNSEDDEPTLKKCKPEPSQTPTTSSLST 310

  Fly   577 -----LDVVGPPQSPLLPLSHSLQQMHAHQHSAALAAW------------FNHLAGAGAGASEHA 624
                 |....|.:||...:...:..|:.:.....||.|            .|..|.|.:..|:|.
 Worm   311 STTPTLSAHHPLRSPQFCIPPPIDMMYQNMPMDLLAHWQMATLFPQFSMALNSPAAAASLLSKHL 375

  Fly   625 AAAAA----NASAEDA 636
            |.|::    .|::||:
 Worm   376 AKASSECKVEATSEDS 391

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bi	NP_001259238.1	Optomotor-blind	<260..318	CDD:287988	4/57 (7%)
		T-box	330..513	CDD:279278	126/182 (69%)
tbx-2	NP_001370674.1	T-box_TBX2_3-like	59..243	CDD:410314	130/186 (70%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166762
Domainoid	1	1.000	280	1.000	Domainoid score	I891
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3847
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002445
OrthoInspector	1	1.000	-	-		oto17978
orthoMCL	1	0.900	-	-		OOG6_105359
Panther	1	1.100	-	-	LDO	PTHR11267
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2837
SonicParanoid	1	1.000	-	-		X1628
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.680