Protein Alignment bi and Tbx10

DIOPT Version :10

• Sequence 1: NP_001259238.1
• Gene: bi / 31379
• FlyBaseID: FBgn0000179
• Length: 1023
• Species: Drosophila melanogaster
• Sequence 2: NP_001001320.1
• Gene: Tbx10 / 109575
• MGIID: 1261436
• Length: 385
• Species: Mus musculus
• Alignment Length: 404
• Identity: 151/404 - (37%)
• Similarity: 195/404 - (48%)
• Gaps: 120/404 - (29%)

  Fly   246 FPAAALAALAGSPAGPHPGLYPGG----GLRFPPHHPGAHPHAHHLGSAYTTAEDVVLASAVAHQ 306
            |.:|.|..||.....|||......    |.|||.            ||...:.|    |.|:|
Mouse     4 FLSAGLGVLAPPETCPHPETSTSWESRLGTRFPS------------GSCTMSTE----AQAMA-- 50

  Fly   307 LHPAMRPLRALQPEDDGV----VDDPKVTLEGKDLWEKFHKLGTEMVITKSGRQMFPQMKFRVSG 367
                       :|...|.    |....|.||.|.|||:|::|||||::||:||:|||..:.::.|
Mouse    51 -----------EPTGQGPKNPRVSSVMVQLEMKPLWEEFNQLGTEMIVTKAGRRMFPTFQVKILG 104

  Fly   368 LDAKAKYILLLDIVAADD--YRYKFHNSRWMVAGKADPEMPKRMYIHPDSPTTGEQWMQKVVSFH 430
            :|..|.|.||:|.:..||  |||.||:|.|:|||||||..|.|::.|||||..|.|||:::|||.
Mouse   105 MDTLADYALLMDFIPLDDKRYRYAFHSSAWLVAGKADPATPGRVHFHPDSPAKGAQWMRQIVSFD 169

  Fly   431 KLKLTNNISDKHGFVSTTILNSMHKYQPRFHLVRAN---DILKLPYSTFRTYVFKETEFIAVTAY 492
            |||||||:.|.:|.:   ||||||:||||||:|..:   |..:.....|:::||.||:|.|||||
Mouse   170 KLKLTNNLMDDNGHI---ILNSMHRYQPRFHVVFVDPRKDSARYAQENFKSFVFTETQFTAVTAY 231

  Fly   493 QNEKITQLKIDNNPFAKGFRDT-----------------------------GAGKREKKQALMSN 528
            ||.:||||||.:||||||||:.                             |:.:|||
Mouse   232 QNHRITQLKIASNPFAKGFREADPDSWPVTPRPLLSIPARSRSSLSPCLLKGSAEREK------- 289

  Fly   529 RGSDSDKLNPTHVSSSRAPLHLGHAGRPPHLHPHAALLDNQQDDDDKLL---------------- 577
               |:.|.:   .||||.|           ..||..||    ...|.||
Mouse   290 ---DTSKAS---ASSSRTP-----------TQPHNQLL----PAPDVLLAPATYRPLPYQNLYPG 333

  Fly   578 --DVVGPPQSPLLP 589
              ...|||::.|.|
Mouse   334 SPSRAGPPRARLAP 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bi	NP_001259238.1	Optomotor-blind	<260..318	CDD:337907	13/61 (21%)
		T-box_TBX2_3-like	326..513	CDD:410314	106/191 (55%)
Tbx10	NP_001001320.1	T-box_TBX1_10-like	65..252	CDD:410313	106/189 (56%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	283..310		13/50 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	328..359		5/20 (25%)