Protein Alignment CG3626 and Pdpr

DIOPT Version :10

• Sequence 1: NP_572162.2
• Gene: CG3626 / 31377
• FlyBaseID: FBgn0029706
• Length: 939
• Species: Drosophila melanogaster
• Sequence 2: NP_938050.1
• Gene: Pdpr / 319518
• MGIID: 2442188
• Length: 878
• Species: Mus musculus
• Alignment Length: 918
• Identity: 385/918 - (41%)
• Similarity: 558/918 - (60%)
• Gaps: 52/918 - (5%)

  Fly    12 VSVVPRRRWCSPGLS--NAVRLSSSQMDPADERVLRKRKFQPQQAADLSEELAGQLPVKSRVVIC 74
            :|:|.|:| .|||..  ::.|.|:|..:                    :..:|  ||.:::||||
Mouse     6 LSIVQRQR-TSPGWQTWSSARSSTSTAE--------------------AHSIA--LPAQAQVVIC 47

  Fly    75 GGGITGASVAYHLGLRGWGGETLLVEQDRVGGELPWTACGLAGRFEPSYTELKLAEYSIDLIKRL 139
            ||||.|.||||||...|| .:.:|:||.|:.........|:......|..|.|:|.||..|..:|
Mouse    48 GGGIMGTSVAYHLSKMGW-QDIVLLEQGRLAAGSTRFCAGILSTARHSSVEQKMANYSNKLYHQL 111

  Fly   140 -AENGLPTGWRPVGSLNLARSWDRMTAFNRMKSQALAWGMHCEILSPEQCAQHCELLSLDGIEGG 203
             .|.|:.||:...||::||::.||:.:..|:.|:....|:..||:||::.|:...||::..:.|.
Mouse   112 EQETGIQTGYLRTGSISLAQTQDRLISLKRINSRLNVVGIPSEIISPKKVAELHPLLNVHDLVGA 176

  Fly   204 LWIPEDGVCDPQLVCQAYMIEAQRLGVRIVEHCAIKKIHSEHGKVRSVETTAGDVECEYFVNCTG 268
            :::|||.|.....|..|....|.:.||:|.:..::..:..:.|:|..|||..|.:||:|||||.|
Mouse   177 MYVPEDAVVSSADVALALASAASQNGVQIYDRTSVLHVLIKKGQVTGVETDKGQIECQYFVNCAG 241

  Fly   269 FWAREVGTLSKPVVKVPLKAVEHHYLHTKPIE-GLSPDTPFVRDFDGRIFFRECEGHILAGGFER 332
            .||.|:|..::..:.:||.|.||.||.|:|.: .|..:||.:.|.||||:.|..:|.||:||||:
Mouse   242 QWAYELGLSNEEPLSIPLHACEHFYLLTRPWDTPLQSNTPTIVDADGRIYIRNWQGGILSGGFEK 306

  Fly   333 EAKMVYEDGVIPLS-QTARQHPPDWDHFHELLDALLLRVPSFRDATLDRLTNSLQVFSPDCKWIL 396
            ..|.::.:|...|. |..|:   |||||..||.:||.|:|:.....:.:|.|..:.|:||.|.|:
Mouse   307 NPKPIFTEGKNQLEIQNLRE---DWDHFEPLLSSLLRRMPALETLEILKLVNCPETFTPDMKCIM 368

  Fly   397 GEAPEIQNYYVAAGNKTMGVSASGGIGRVLTDLITKGSTYLDLHILDISRFLGLHNNRKFLRDRC 461
            ||:|.:|.|:|.||..:.|:|..||.|:.|.:.:..|....::..||:.||..|.::|.|||.|.
Mouse   369 GESPVVQGYFVLAGMNSAGLSLGGGAGKFLAEWMVYGYPSENVWELDLQRFGALQSSRTFLRHRV 433

  Fly   462 KEAPGKHFEINYPFEEFQTGRNLRMSPIYPQLKEAGAVFGQSMGYERPNYFDQQDKHDEFGLPRF 526
            .|.....:::..|..:|||||.||.||:|.:|...||.:.:..|:|||.||...:|      ...
Mouse   434 MEVMPLIYDLKVPRWDFQTGRQLRTSPLYDRLDAQGARWMEKHGFERPKYFVPPNK------DLL 492

  Fly   527 RIAQTRTFGKPPWFDHVASEYRACRERIGIADYSSFTKYDFWSKGNEVVDLLQYLCSNDVDVAVG 591
            .:.|::||.||.|||.|.||.:.|:|.:.:.|.|||||::..|.|:|.::.||||..||:||.||
Mouse   493 ALEQSKTFYKPDWFDIVESEVKCCKEAVCVIDMSSFTKFEITSTGDEALESLQYLFCNDLDVPVG 557

  Fly   592 SIIHTGMQNPNGGYENDCSLARLSERHYMMIAPTIQQTRSMCWIRKHMPNHLRAKVNVADVTSMY 656
            .|:||||.|..||||||||:|||::|.:.||:||.||.....|:.|::|..  :.:.:.|||..|
Mouse   558 HIVHTGMLNEYGGYENDCSIARLTKRSFFMISPTDQQVHCWAWLNKYLPKD--SNLLLEDVTWKY 620

  Fly   657 TAICILGPYSRILLSELTDTDLTPKSFPFFTYKELDVGLADGIRVLNITHTGELGYVLYIPNEYA 721
            ||:.::||.:..:||||:...:||..||....||:.||.|:||||:::|||||.|::||||.|||
Mouse   621 TALNLIGPRAVDVLSELSYAPMTPDHFPTLFCKEMSVGYANGIRVMSMTHTGEPGFMLYIPIEYA 685

  Fly   722 LHVYSRLYQAGQKFNIQHAGYYATRALRIEKFYAFWGQDLDTFTTPLECGRSWRVKFNKPIDFIG 786
            ||||:.:...|||:.|::|||||.|:||||||:|||||||:|.|||||||...|||..|.|||||
Mouse   686 LHVYNEVMSVGQKYGIRNAGYYALRSLRIEKFFAFWGQDLNTLTTPLECGGESRVKLEKGIDFIG 750

  Fly   787 RNALLKQREEGVKRMYVQLLLNDHDHEVDMWCWGGEPIYRDGVYVGMTTTTGYGYTFEKQVCLGF 851
            |:|||:|::.||.:.....:|:|||.::|:|.|.||||||:|.|.|.||::.|.||.|:.||||:
Mouse   751 RDALLQQKQTGVYKRLAMFILDDHDTDLDLWPWWGEPIYRNGKYAGKTTSSAYSYTLERHVCLGY 815

  Fly   852 VRNF-DDEGRELPVTNEYVLSGHYEVEVAGVRFEAKVNLHSPNLPTKFPDREREAYHATRDKPDQ 915
            |.|| :|.|.|..||.:::..|.||:::||.||:||..|:.   .|.|...:|        :.|.
Mouse   816 VHNFSEDSGEEQVVTTDFINRGEYEIDIAGHRFQAKAKLYP---VTSFFTHKR--------RKDD 869

  Fly   916 ADLLSYGG 923
            .:|..:.|
Mouse   870 VELSDFHG 877

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3626	NP_572162.2	DadA	70..446	CDD:440429	144/378 (38%)
		FAO_M	432..487	CDD:465100	20/54 (37%)
		GcvT	481..904	CDD:440173	211/423 (50%)
Pdpr	NP_938050.1	DadA	40..384	CDD:440429	135/347 (39%)
		FAO_M	405..459	CDD:465100	20/53 (38%)
		GcvT	453..867	CDD:440173	212/432 (49%)