Protein Alignment CG3626 and dmgdh

DIOPT Version :10

• Sequence 1: NP_572162.2
• Gene: CG3626 / 31377
• FlyBaseID: FBgn0029706
• Length: 939
• Species: Drosophila melanogaster
• Sequence 2: XP_073791697.1
• Gene: dmgdh / 100141496
• ZFINID: ZDB-GENE-080227-8
• Length: 862
• Species: Danio rerio
• Alignment Length: 923
• Identity: 273/923 - (29%)
• Similarity: 426/923 - (46%)
• Gaps: 89/923 - (9%)

  Fly     1 MWKLLQRSGNAVSVVPRRRWCSPGLSNAVRLSSSQMDPADERVLRKR----KFQPQQAADLSEEL 61
            ||:.|  ||...||  ||.|                   ..||.|:|    ...|::|:  :..|
Zfish     1 MWRTL--SGLKASV--RRHW-------------------RRRVPRERARSFATDPREAS--AGVL 40

  Fly    62 AGQLPVKSRVVICGGGITGASVAYHLGLRGWGGETLLVEQDRVGGELPWTACGLAGRFEPSYTEL 126
            |.:|...:..::.|||..|.||||||...|.....||.:.:...|. .|.|.||...:.|.....
Zfish    41 ARRLQDSADTLVIGGGCVGVSVAYHLAKAGQKDVVLLEKSELTAGS-TWHAAGLTTYYHPGINLK 104

  Fly   127 KLAEYSIDLIKRL-AENGLPTGWRPVGSLNLARSWDRMTAFNRMKSQALAWGMHCE---ILSPEQ 187
            |:..|||.|.::| ||.|...|:...||:.||.:..|:   :.:|.|......|..   ::.||:
Zfish   105 KIHYYSIKLFEQLEAETGQAVGFHQPGSIRLASTPVRV---DELKYQMSRTRWHPTPQFLIEPER 166

  Fly   188 CAQHCELLSLDGIEGGLWIPEDGVCDPQLVCQAYMIEAQRLGVRIVEHCAIKKI-HSEHGKVRSV 251
            ..|...||::|.:..||:.|.||..||..:..|....|:..|.:|....|:..: .:|.|: ..|
Zfish   167 IQQLFPLLNMDKVLAGLYNPGDGHIDPYSLTMALAAGARMYGAQIYCPAAVTGLTPTEDGR-WDV 230

  Fly   252 ETTAGDVECEYFVNCTGFWAREVG-TLSKPVVKVPLKAVEHHYLHT---KPIEGLSPDTPFVRDF 312
            :|..|.:.....||.|||||||:| .|..|...||   |.|.|:.|   ..::.|..:.|.:||.
Zfish   231 QTPHGTIRANRIVNATGFWARELGQMLGFPHPTVP---VHHQYVVTGSVPEVQALQTELPVIRDL 292

  Fly   313 DGRIFFRECEGHILAGGFEREAKMVYEDGVI----PLSQTARQHPPDWDHFHELLDALLLRVPSF 373
            :|..:.|:....:|.|.:|||.||..:|..|    |..........|.|...:.::..:..||..
Zfish   293 EGSYYLRQERDGLLFGPYEREEKMKLQDSWITDGVPAGFGKELFESDLDRIMDHVEMAMEMVPVL 357

  Fly   374 RDATLDRLTNSLQVFSPDCKWILGEAPEIQNYYVAAGNKTMGVSASGGIGRVLTDLITKGSTYLD 438
            ::|.:..:.:....::||...::|.....:||:.|.| ...|:..|||:||.|:|.|..|....|
Zfish   358 KNADIINIVSGPITYTPDLLPMIGPHQGARNYWTAIG-FGYGIIHSGGVGRFLSDWIINGEPPYD 421

  Fly   439 LHILDISRFLGLHNNRKFLRDRCKEAPGKHFEINYPFEEFQTGR-NLRMSPIYPQLKEAGAVFGQ 502
            |...|.:|: |......::..:.:|:.|.:..:.:|.||...|| .:|:|.:|..||...:: |.
Zfish   422 LIECDPNRY-GHWTTVPYVCAKARESYGFNNVVGFPKEERFAGRPTVRVSGVYELLKHRCSM-GF 484

  Fly   503 SMGYERPNYFDQQDKHDEFGLPRFRIAQTRTFGKPPWFDHVASEYRACRERIGIADYSSFTKYDF 567
            ..|:|:|:||.:...|..: .|.||        :..||..|..|.....:.:|:.|.|.|.|...
Zfish   485 HSGWEQPHYFHKPGDHTGY-RPSFR--------RTNWFAPVGRECAQVMQAVGVIDLSPFGKMKV 540

  Fly   568 WSKGNEVVDLLQYLCSNDVDVAVGSIIHTGMQNPNGGYENDCSLARLSERHYMMIAPTIQQTRSM 632
            ....:|  .||..|.:|.:. .||....:.|..|.|....:.::.......:::|..:..:...:
Zfish   541 TGADSE--RLLDRLLANTLP-KVGQTNISHMLTPRGRVYAELTVTHTQPGEFLLITGSGSELHDL 602

  Fly   633 CWIRKHMPNHLRAKVNVADVTSMYTAICILGPYSRILLSELTDTDLTPKSFPFFTYKELDVGLAD 697
            .||.:...:. ...|.|.:||.....:.|.||.||.:|.:||..||:..||.|...:.:::..|.
Zfish   603 RWIEREAADG-GYDVCVTNVTDEIGVLGIAGPKSRTVLQKLTSADLSESSFRFLQCRTIELAGAT 666

  Fly   698 GIRVLNITHTGELGYVLYIPNEYALHVYSRLYQAGQKFNIQHAGYYATRALRIEKFYAFWGQDLD 762
             ::.:.|::|||||:.||:.......||..|.:||:..||...|.||..:||:||.:..||.:::
Zfish   667 -VQAIRISYTGELGWELYMDMRNMSAVYQALMEAGRDENIDDFGTYAMNSLRLEKGFRAWGAEMN 730

  Fly   763 TFTTPLECGRSWRVKFNKPIDFIGRNALLKQREEGVKRMYVQLLLNDHDHEVDMWCWGGEPIYRD 827
            ..|.|||.|..:.:|.|||.||||:.|||:.:.:|:.|....|.||..|.:.:    |.|.::.:
Zfish   731 CDTNPLEAGLDYFIKLNKPADFIGKQALLEIKAQGLSRRLAFLTLNTDDIDPE----GNESVWHN 791

  Fly   828 GVYVGMTTTTGYGYTFEKQVCLGFVRNFDDEGRELPV--TNEYVLSGHYEVEVAGVRFEAKVNLH 890
            |..||.||:..|.|:..:.:...:          |||  |.   |....|||:.|.::.|.|. .
Zfish   792 GEVVGNTTSGSYSYSTHQSLAFAY----------LPVGLTQ---LGQKVEVELLGQKYSATVT-K 842

  Fly   891 SPNLPTKFPDRER 903
            .|.:.|: |.|.|
Zfish   843 EPLILTE-PARTR 854

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3626	NP_572162.2	DadA	70..446	CDD:440429	119/388 (31%)
		FAO_M	432..487	CDD:465100	14/55 (25%)
		GcvT	481..904	CDD:440173	128/426 (30%)
dmgdh	XP_073791697.1	None