Protein Alignment norpA and plcd4a

DIOPT Version :10

• Sequence 1: NP_525069.2
• Gene: norpA / 31376
• FlyBaseID: FBgn0262738
• Length: 1095
• Species: Drosophila melanogaster
• Sequence 2: XP_073793517.1
• Gene: plcd4a / 565669
• ZFINID: ZDB-GENE-050208-654
• Length: 768
• Species: Danio rerio
• Alignment Length: 852
• Identity: 260/852 - (30%)
• Similarity: 400/852 - (46%)
• Gaps: 150/852 - (17%)

  Fly     3 KKYEFDWIIPVPPELTT---GCVFDRWFENEKETKENDFERDALFKVDEYGFFLYWKSEGRDGDV 64
            :|:..::.|....:|.:   |.|.       ::.|...:::...|::.|....::::|: :.|:.
Zfish    14 RKFHLNYGIQADDDLKSMIVGTVM-------RKIKSRTWKKQRYFRLQEDCMTIWYQSK-KAGNA 70

  Fly    65 IELCQVSDIRAGGTPKDPKILDKVTKKNGTNIPELDKRSLTIC-----SNTDYINITYHHVICPD 124
            .....|.|:.|.......::|..:..:    .|  ..|..|:.     .|.|        ::...
Zfish    71 HSTFSVGDVEAVREGHQSEVLLSIADE----FP--PDRCFTLVFRGRRGNLD--------LVAES 121

  Fly   125 AATAKSWQKNLRLITHNNRATNVCPRVNLMKHWMRLSYC-------VEKSGKI---PVKTLAKTF 179
            ...|:||.|.:|.:..|  ..|:..|..| ..|:    |       ..:.|::   .|:.|.|..
Zfish   122 TKEAQSWIKGIRKLIDN--LENMGQREKL-DQWI----CDWFKKADKNRDGRMNFKEVRDLLKMM 179

  Fly   180 ASGKTEKLVYTCIKDAGLPDDKNATMTKEQFTFDKFYALYHKVCPRNDIEELFTSITKGKQDFIS 244
            .....|.........|    |::.:.|.|.   |:|...|..:..|.||..:|...:...|. ::
Zfish   180 NVDMNEHHALRLFTMA----DRSQSGTLED---DEFVLFYKMLTQREDILRVFQEYSADGQK-LT 236

  Fly   245 LEQFIQFMNDKQRDPRMNEILYPLYE---EKRCTEIINDYELDEEKKKNVQMSLDGFKRYLMSDE 306
            |:....|:.::|           |:|   ::....:|..:|..:..|....|:.|||..||.|.|
Zfish   237 LKDLKDFLQEEQ-----------LHEDGVQQYALNLIERFEPSDTAKMLQAMTFDGFLMYLSSSE 290

  Fly   307 NAPVFLDRLDFYMEMDQPLAHYYINSSHNTYLSGRQIGGKSSVEMYRQTLLAGCRCVELDCWNGK 371
            .:......|:.|.:|.|||.||:|:|||||||...||.|.||||.|.:.|..||||||:|||:
Zfish   291 GSIFNPAMLELYQDMSQPLCHYFISSSHNTYLLEDQIRGLSSVEGYIRALKRGCRCVEVDCWD-- 353

  Fly   372 GEDEEPIVTHGHAYCTEILFKDCIQAIADCAFVSSEYPVILSFENHCNRAQQYKLAKYCDDFFGD 436
            |.:.||||.|||.:.::|.|||.:..:.:.:|.:||||||||.||||:..||..:|::.....||
Zfish   354 GPNGEPIVYHGHTFTSKIFFKDVVTVLGNYSFKASEYPVILSIENHCSVEQQKIMAQHLTQILGD 418

  Fly   437 LLLKEPLPDHPLDPGLP--LPPPCKLKRKILIKNKRMKPEVEKVELELWLKGELKTDDDP----- 494
            .|||.     .||..:|  ||.|..||.|||:|.|::.      .||..:.|.:   |||
Zfish   419 KLLKS-----TLDGKIPLGLPSPEDLKGKILLKGKKIG------GLEDGMNGVV---DDPLMGEV 469

  Fly   495 --EEDASAGKPPEAAAAPAPAPEAAAAAEGAAEGGGGAEAEAAAANYSG---------STTNVHP 548
              ||:|:                                 |....|:..         |...:..
Zfish   470 SDEEEAT---------------------------------EIEDENHRNNSIRHRSKKSKQRLSK 501

  Fly   549 WLSSMVNYAQPIKFQGFDKAIEKNIAHNMSSFAESAGMNYLKQSSIDFVNYNKRQMSRIYPKGTR 613
            .||..|.|.:.:.|..|..:...:..:.:|||.||....:::::..:||.:|.||:||:||.|.|
Zfish   502 ELSDCVVYCKSVHFSSFKHSRNHSKFYEISSFTESKARKHIREAGAEFVLHNARQLSRVYPSGLR 566

  Fly   614 ADSSNYMPQVFWNAGCQMVSLNFQSSDLPMQLNQGKFEYNGGCGYLLKPDFMRRADKDFDPFADA 678
            .||||:.||..||||||:|:||||::.:.|.||.|.|..||.|||:|||.|||..::.|||....
Zfish   567 TDSSNFNPQDLWNAGCQIVALNFQTAGVEMDLNDGLFNQNGRCGYVLKPAFMRNFEEMFDPENPQ 631

  Fly   679 PVDGVIAAQCSVKVIAGQFLS--DKKVGT----YVEVDMFGLPSDTVKKEFRTRLVANNGLNPVY 737
            ..:.......|::||:||.|.  :.|.|:    :|.|::.|:|.|..|:|  ||.:.|||.|||:
Zfish   632 NREDYKPLSLSIQVISGQQLPKVNIKEGSIIDPFVRVEIHGVPLDQAKQE--TRYIDNNGFNPVW 694

  Fly   738 NEDPFVFRKVVLPDLAVLRFGV--YEESGK--ILGQRILPLDGLQAGYRHVSLRTEANFPMSLPM 798
             .|...| .:..|:||::||.|  |:::.|  .:||..||...:|.||||:.|.::....:....
Zfish   695 -YDTLQF-TIHAPELALVRFVVEDYDKTSKNDFVGQFTLPFTCIQPGYRHIHLLSKDGTSIPPSS 757

  Fly   799 LFVNIEL 805
            |||:|.:
Zfish   758 LFVHIRI 764

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
norpA	NP_525069.2	PH_PLC_beta	17..149	CDD:270167	24/139 (17%)
		EFh_NorpA_like	154..306	CDD:320042	34/164 (21%)
		EF-hand motif	154..183	CDD:320042	6/38 (16%)
		EF-hand motif	189..218	CDD:320042	6/28 (21%)
		EF-hand motif	227..256	CDD:320042	6/28 (21%)
		EF-hand motif	273..306	CDD:320042	10/32 (31%)
		PI-PLCc_beta	318..653	CDD:176533	135/352 (38%)
		C2_PLC_like	689..806	CDD:175974	47/127 (37%)
		DUF1154	865..909	CDD:461969
		PLC-beta_C	952..1073	CDD:462571
plcd4a	XP_073793517.1	None