Protein Alignment norpA and plcl5

DIOPT Version :9

• Sequence 1: NP_001014720.1
• Gene: norpA / 31376
• FlyBaseID: FBgn0262738
• Length: 1095
• Species: Drosophila melanogaster
• Sequence 2: XP_002661169.2
• Gene: plcl5 / 327464
• ZFINID: ZDB-GENE-030131-5675
• Length: 1122
• Species: Danio rerio
• Alignment Length: 1113
• Identity: 287/1113 - (25%)
• Similarity: 459/1113 - (41%)
• Gaps: 263/1113 - (23%)

  Fly    31 KETKENDFERDALFKVDEYGFFLYWKSEGRDGD--VIELCQVSDIRAGGTPKDPKILDKVTKKNG 93
            |:.:.|....:..|.:|....:|.|:...:|.:  .:|:..:.::|.|  .|.|     |.:.||
Zfish   138 KKVRSNSRMYNRYFLLDPDMRWLRWEPSKKDSEKAKLEIKSIKEVRLG--KKTP-----VLRSNG 195

  Fly    94 TN--IPELDKRSLTICSNTDYINITYHHVICPDAATAKI---WLDGIRKIT----HNV-KANNIC 148
            .:  .||....|:....|.:.:::.        |:||.:   |:.|:|.:.    |.| .|....
Zfish   196 LSDQFPEECAFSIIYGDNYESLDLV--------ASTADVVSTWVMGLRYLVSYGRHMVGVAEPSQ 252

  Fly   149 PMMCLRKHWMRLSYCV---EKSGKIPV---KTLAKTFASGKTEKLVYTCIKDAGLPDDKNATMTK 207
            |  .:|..|:...:.:   |:.|.|.:   ..:.|....|..|..:....|:.    .|......
Zfish   253 P--SVRTSWIGSVFDLADPERQGHIDLFRATQIIKGLNPGMRESRIELKFKEL----QKAKDCYG 311

  Fly   208 EQFTFDKFYALYHKVCPRNDIEELFTSITKGKQ--------DFISLEQFIQFMNDKQRDPRMNEI 264
            |....|.|...|.::|.|::|..|....:..|:        .|:.:||.::.:.
Zfish   312 EGIDLDTFVEAYCELCTRSEIFFLLVQFSSNKEYLDSKDLMIFVEVEQGVEGVT----------- 365

  Fly   265 LYPLYEEKRCTEIINDYELDEEKKKNVQMSLDGFKRYLMSDENAPVFLDRLDFYMEMDQPLAHYY 329
                  |:.|.||::.||...|.:.|..:|:|||..||:|.|.............:|.|||:|||
Zfish   366 ------EEMCREIVHKYEPSAEGRNNGYLSIDGFTHYLLSSECHIFDPQHKHVCQDMTQPLSHYY 424

  Fly   330 INSSHNTYLSGRQIGGKSSVEMYRQTLLAGCRCVELDCWNGKGEDEEPIVTHGHAYCTEILFKDC 394
            ||||||..|......|.|.:..|.:.|..|||.:|:..|:  |.|.||:|..|.:..:::.|...
Zfish   425 INSSHNASLLEDHYWGSSDLSSYVRALRMGCRSLEVVVWD--GPDCEPVVYVGSSVASQLAFCKI 487

  Fly   395 IQAIADCAFVSSEYPVILSFENHCNRAQQYKLAKYCDDFFGDLL-LKEP-LPDHPLDPGLPLPPP 457
            :..|...||.|||||:||....||:..||..:|::.....||.| ::.| |.||      .||.|
Zfish   488 LDVINQYAFESSEYPLILCLVTHCSVPQQRVMAQHLKKILGDKLHIESPNLEDH------YLPSP 546

  Fly   458 CKLKRKILIKNKRMKPEVEKVELELWLKGELKTDDDPEEDASAGKPPEAAAAPAPAPEAAAAAEG 522
            .|||.|:|||.||:..:.:..|      ||: ||   ||:..               |.:....|
Zfish   547 DKLKGKVLIKGKRLPTDSQDSE------GEV-TD---EEEGF---------------EMSRRMMG 586

  Fly   523 AAE----GGGGAEAEAAAANYSGSTTNVHPWLSSMVNYAQPIKFQGFDKAIEKNIAHNMSSFAES 583
            ..:    .|.|.:.......           ||.:|...:.::|:.|:.:..:.....:.||.|.
Zfish   587 VDDKDHLNGIGCKRLRLCKE-----------LSDLVTLCKSVQFRDFEMSKREQKHWEICSFNEV 640

  Fly   584 AGMNYLKQSSIDFVNYNKRQMSRIYPKGTRADSSNYMPQVFWNAGCQMVSLNFQSSDLPMQLNQG 648
            ....:..:...|||:||||.:||:||...|.|:||..||.||..|||:|::|:|:..|.|.||.|
Zfish   641 DANRFANEFPEDFVSYNKRFLSRVYPTPMRIDASNMNPQDFWKCGCQIVAMNYQTPGLMMDLNLG 705

  Fly   649 KFEYNGGCGYLLKPDFMRRADKDFDPFADAPVDGVIAAQCSVKVIAGQFLSDKK--------VGT 705
            .|..||.|||:|:|..||.....|...|...:.||.|....:|||:||.|...:        |..
Zfish   706 WFRQNGNCGYVLRPAIMREEVSYFSANARDSLPGVSAQLLHIKVISGQNLPKPRGSAAKGDVVEP 770

  Fly   706 YVEVDMFGLPSDTVKKEFRTRLVANNGLNPVYNEDPFVFRKVVLPDLAVLRFGVYEE---SGKIL 767
            |:.|::.|:|:|..  |.||:.|:.||.||:::|. |.| ::.||:||||||.|.::   ..:.:
Zfish   771 YIYVEIHGIPADCA--EQRTKTVSQNGDNPIFDES-FEF-QINLPELAVLRFVVLDDDYIGDEFI 831

  Fly   768 GQRILPLDGLQAGYRHVSLRTEANFPMSLPMLFVNIELKIYVPDGFEDFMAMLSDPRGFAGAAKQ 832
            ||..:|.:.|..|||||.|::.....:....|||::
Zfish   832 GQYTIPFECLLPGYRHVPLQSLTGEFLPNTTLFVHV----------------------------- 867

  Fly   833 QNEQMKALGIEEQSGGAARDAGKAKEEEKKEPPLVFEPVTLESLRQEKGFQKVGKKQIKELDTLR 897
                    .|..:.||                                     ||...:.|...:
Zfish   868 --------AITNRRGG-------------------------------------GKAHKRGLSVRK 887

  Fly   898 KKHAKERTSVQKTQNAAIDKLIKGKSKDDIRNDANIKNSINDQTKQWTDMIARHRKEEWDMLRQH 962
            .:.|:|.||.:.|....:|:|.:..::               ..::.||            ||::
Zfish   888 GRKAREYTSTKTTGIKVVDELFRASTQ---------------PLREATD------------LREN 925

  Fly   963 VQDSQDAMKALMLTVQAAQIKQL----------EDRHARDIKDLNAKQAKMSA------------ 1005
            ||::..:.|.|.....||.:||.          .:|..|...||:.....|.|
Zfish   926 VQNAMVSFKELCGLTPAANMKQCILTVSSWLMNSERVLRVTVDLSEAYPTMEAHGPIPELLRKVL 990

  Fly  1006 ---DTAKEVQNDKTL-KTKNEKDRRLREKRQNNVKRFMEEKKQIGVKQGRAMEKLKLAHSKQIEE 1066
               ||.  :|..:|| ::.:....:|.:.::..:. |.|:..:||.::|....||:    |.:|.
Zfish   991 TAYDTM--IQTSRTLIESADGVYSKLTQAQRAGLD-FHEDLHRIGAREGLKGRKLQ----KAMES 1048

  Fly  1067 FSTDVQKL 1074
            ::.::..|
Zfish  1049 YAWNITVL 1056

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
norpA	NP_001014720.1	PH_PLC_beta	17..149	CDD:270167	28/129 (22%)
		PLN02952	224..786	CDD:178538	192/586 (33%)
		EF-hand_like	227..318	CDD:286375	22/98 (22%)
		PI-PLCc_beta	318..653	CDD:176533	114/340 (34%)
		C2_PLC_like	689..806	CDD:175974	45/127 (35%)
		DUF1154	866..908	CDD:284131	7/41 (17%)
		Mer2	<887..1003	CDD:286200	25/125 (20%)
plcl5	XP_002661169.2	PH	131..239	CDD:278594	25/115 (22%)
		PH_PLC_eta	131..239	CDD:270170	25/115 (22%)
		PLN02228	324..872	CDD:177873	198/649 (31%)
		EF-hand_like	331..413	CDD:286375	22/98 (22%)
		PI-PLCc_PRIP_metazoa	413..710	CDD:176539	114/340 (34%)
		C2_PLC_like	742..870	CDD:175974	46/168 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0169
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D368239at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820