Protein Alignment norpA and plch1

DIOPT Version :9

• Sequence 1: NP_001014720.1
• Gene: norpA / 31376
• FlyBaseID: FBgn0262738
• Length: 1095
• Species: Drosophila melanogaster
• Sequence 2: XP_031758196.1
• Gene: plch1 / 100497252
• XenbaseID: XB-GENE-6042445
• Length: 1661
• Species: Xenopus tropicalis
• Alignment Length: 1256
• Identity: 325/1256 - (25%)
• Similarity: 528/1256 - (42%)
• Gaps: 338/1256 - (26%)

  Fly    21 CVFDRWFENEKETKENDFERDALFKVDEYGFFLYWKSEGRDGDVIELCQVSDIRAGGTPKDPKIL 85
            |:  ||..:.|..|.. ...|:::||          :|||..::..       |......||...
 Frog    62 CI--RWRPSRKSEKAK-IIIDSIYKV----------TEGRQSEIFH-------RHAEGNFDPSCC 106

  Fly    86 DKVTKKNGTNIPELDKRSLTICSNTDYINITYHHVICPDAATAKIWLDGIRKITHNVK-ANNICP 149
              .|..:|.::..||    .|.||.:               .|:.|:.|::.:...:. .:::..
 Frog   107 --FTIYHGNHMESLD----LITSNPE---------------EARTWITGLKYLMAGISDEDSLAK 150

  Fly   150 MMCLRKHWMRLSY-CVEKSG------------------KIPVKTLAKTFASGKTEKLVYTCIKDA 195
            .......|::.:: ..:|:|                  .:|.:.:.:.|....|
 Frog   151 RQRTHDQWVKQTFEEADKNGDGLLNIEEIYQLMHKLNVNLPRRKVRQMFQEADT----------- 204

  Fly   196 GLPDDKNATMTKEQFTFDKFYALYHKVCPRNDIEELFTSITKGKQDFISLEQFIQFMNDKQRDPR 260
               |:...|:     ||::|...|..:..|.|:..|..:.: .|:|.::::...||...:|   :
 Frog   205 ---DENQGTL-----TFEEFSVFYKMMSLRRDLYLLLLNYS-DKKDHLTVDDLAQFFKVEQ---K 257

  Fly   261 MNEILYPLYEEKRCTEIINDYELDEEKKKNVQMSLDGFKRYLMSDENAPVFLDRLDFYMEMDQPL 325
            ||.:     ..:.|.:||..:|:.||.|:...:.:|||..::.|...........:.|.:|||||
 Frog   258 MNNV-----TTEYCIDIIQKFEVSEENKEQHVLGIDGFTNFMRSPAGDIFNPQHCEIYQDMDQPL 317

  Fly   326 AHYYINSSHNTYLSGRQIGGKSSVEMYRQTLLAGCRCVELDCWNGKGEDEEPIVTHGHAYCTEIL 390
            ..|||.|||||||:|.|:..:|.|:||...|..||||:|:|||:  |.|.||:|.||:...:::|
 Frog   318 CSYYIASSHNTYLTGDQLLSQSKVDMYAWVLQDGCRCIEVDCWD--GPDGEPVVHHGYTLTSKVL 380

  Fly   391 FKDCIQAIADCAFVSSEYPVILSFENHCNRAQQYKLAKYCDDFFGDLLLKEPLPDHPLDPGLPLP 455
            |||.::.|...|||.:|||||||.|||||..||.|:|:|..|.|||   |..|...||.....||
 Frog   381 FKDVVETINKHAFVKNEYPVILSIENHCNIQQQRKIAQYMKDIFGD---KLDLSSVPLGESKQLP 442

  Fly   456 PPCKLKRKILIKNKRM------------------KPEVE----------------------KVEL 480
            .|..||.|||:|.|::                  ..|:|                      :.:|
 Frog   443 SPQNLKGKILVKGKKLPYDLADDAEEGEVSDEDSADEIEEECKLTQCFSNGTTEHQVESFIRKKL 507

  Fly   481 ELWLK-GELKTDDDP-----------------------EEDASAGKPPEAAAA------------ 509
            |..|| .:::..:||                       ::....||...::..
 Frog   508 ESLLKESQIRDKEDPDSFTVKALLKATHEGLNVNLKQNDDTKDCGKSKRSSVGSIAKHKKASKSR 572

  Fly   510 -----------PAPAPEAAAAAEGAAEGGG--------GAEAEAAAANY----SGSTTNVHPWLS 551
                       .:|....|.|...:....|        |.|.:...|||    ...|..:...||
 Frog   573 SKSCSTSDDEDSSPKETTAQAHRWSQATYGILLTCAWIGGEEDVEYANYRLGRRRKTMKLCRALS 637

  Fly   552 SMVNYAQPIKFQGFDKAIEKNIAHNMSSFAESAGMNYLKQSSIDFVNYNKRQMSRIYPKGTRADS 616
            .:|.|...:..|..   ::...:.|:.||:|:.....::..|...:.||::|::||||...|.||
 Frog   638 DLVVYTNSVAAQDI---VDDGTSGNVLSFSETRAHQVVQHKSEQLMLYNQKQLTRIYPSAYRIDS 699

  Fly   617 SNYMPQVFWNAGCQMVSLNFQSSDLPMQLNQGKFEYNGGCGYLLKPDFMRRADKDFDPFADAPVD 681
            ||:.|..:||||.|:|:||:|:....|:||:.||:.||||||:|||..|.:.  .|:.|:..|:.
 Frog   700 SNFNPVAYWNAGIQLVALNYQTEGRMMELNRAKFKMNGGCGYVLKPQQMCKG--VFNQFSADPLP 762

  Fly   682 GVIAAQCSVKVIAGQ--------FLSDKK--VGTYVEVDMFGLPSDTVKKEFRTRLVANNGLNPV 736
            .....|..:|:|:||        .|.|:.  :..:|||::.|||.|..|::  ||:|.:||.|||
 Frog   763 ASPKKQLILKIISGQQLPKPPDSMLGDRGEIIDPFVEVEIIGLPVDCCKEQ--TRVVDDNGFNPV 825

  Fly   737 YNEDPFVFRKVVLPDLAVLRFGVYEES--GK-ILGQRILPLDGLQAGYRHVSL--RTEANFPMSL 796
            : |:...| .|.:|::|::||.|::..  |: .:|||.:..:.|..|||||.|  .|||:
 Frog   826 W-EETLTF-TVHMPEIALVRFLVWDHDPIGRDFVGQRTVAFNSLMPGYRHVYLDGLTEAS----- 883

  Fly   797 PMLFVNIEL-KIYVPDGFEDFMAMLSDPR----GFAGAAKQQ---------NEQMKALGIEEQSG 847
              :||::.: :||     ..:..::.:|.    .|.||.|.:         |...|...:|..|.
 Frog   884 --IFVHVTINEIY-----GKWSPLILNPSYTILHFLGATKNRQFIGLKGFFNRSSKHSSVESNSH 941

  Fly   848 GAARDAG--------KAKEEEKKEPPLVFEPVTLESLRQEKGFQKVGKKQI-------KELDTLR 897
            ...:..|        .|..:.:|:..:||:..| ||            |.|       ||.|.:|
 Frog   942 VRKKSIGDRILRRSASAPAKARKKTKMVFQEST-ES------------KDIVCETSGAKERDFMR 993

  Fly   898 KKHAKERTSVQ-KTQNAAIDKLIKGKSKDDIRNDANIKNSINDQTK------QWTDMIARHRKEE 955
            |:.::   |:| :..:..:|||:.|..:..       .:.|:.:|:      ...:|.|:| :|:
 Frog   994 KRTSR---SLQARPVSMPVDKLLLGAFEPS-------TSEISKETRSDIASGSAGEMQAKH-QEK 1047

  Fly   956 WDM----LRQH-----VQDSQDAMKALMLTVQAA--------QIKQLEDRHARDIKDLNAKQAKM 1003
            .:|    |..|     :|.|....|....|....        :...||.::..||::||
 Frog  1048 PEMTKLDLPVHKNNLAIQHSSPLFKDCHQTENPVNKPVHKKWRSLHLEKQNYDDIRELN------ 1106

  Fly  1004 SADTAKEVQNDKTLKTK--NEKDRRLREKRQNNVKRFMEEKKQIGVKQGRAMEKLKLAHSKQIEE 1066
              ||.....:::.||.|  |||:..|...:..::.                 |..|  |..:.:.
 Frog  1107 --DTFTSESDEEILKPKEGNEKEAMLLLDKMESIP-----------------ENTK--HHAKADL 1150

  Fly  1067 FS-TDVQKLM--DMYKIEEEA 1084
            || ||:...:  ||..::..|
 Frog  1151 FSVTDLSSTICTDMNHLQSTA 1171

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
norpA	NP_001014720.1	PH_PLC_beta	17..149	CDD:270167	24/128 (19%)
		PLN02952	224..786	CDD:178538	213/673 (32%)
		EF-hand_like	227..318	CDD:286375	20/90 (22%)
		PI-PLCc_beta	318..653	CDD:176533	138/433 (32%)
		C2_PLC_like	689..806	CDD:175974	46/132 (35%)
		DUF1154	866..908	CDD:284131	13/48 (27%)
		Mer2	<887..1003	CDD:286200	32/146 (22%)
plch1	XP_031758196.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D368239at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920