Protein Alignment norpA and plcl1

DIOPT Version :9

• Sequence 1: NP_001014720.1
• Gene: norpA / 31376
• FlyBaseID: FBgn0262738
• Length: 1095
• Species: Drosophila melanogaster
• Sequence 2: XP_012826838.2
• Gene: plcl1 / 100495595
• XenbaseID: XB-GENE-6468167
• Length: 1059
• Species: Xenopus tropicalis
• Alignment Length: 1106
• Identity: 290/1106 - (26%)
• Similarity: 473/1106 - (42%)
• Gaps: 255/1106 - (23%)

  Fly    31 KETKENDFERDALFKVDEYGFFLYWKSEGRDGD--VIELCQVSDIRAGGTPKDPKILDKVTKKNG 93
            |:.:.|.......|.:|.....|.|:...:|.:  .:::..:.:||.|..       .:..:.||
 Frog    86 KKVRPNSRIYSRFFTLDPDLQALRWEPSKKDPEKAKLDISAIKEIRLGKN-------TETFRNNG 143

  Fly    94 TNIPELDKRSLTICSNTDYINITYHHVICPDAATAKIWLDGIR-KITH------NVKANNICPMM 151
            ......:..:|:|....:|.::   .::...|..|.||:.|:| .::|      :|:.....|
 Frog   144 LADQICEDSALSIIHGENYESL---DLVANSADVANIWVSGLRYLVSHSKQPLDSVEGGQNTP-- 203

  Fly   152 CLRKHWMRLSY---CVEKSGKIPVKTLAKTFASGKTEKLVYTCIKDAGLP-DDKNATMTKEQFTF 212
              |..|:...:   .|:.:|.:...|..:..      |.:...||:|.:. ..|....:||:.|.
 Frog   204 --RLQWLNSVFEAADVDGNGIMLEDTAVELI------KQLNPAIKEAKVRLKFKEIQKSKEKLTT 260

  Fly   213 ----DKFYALYHKVCPRNDIEELFTSITKGKQDFISLEQFIQFMNDKQRDPRMNEILYPLYEEKR 273
                ::||..:.::|.|.::..|...|:|.| :::.....:.|:..:|   .|.::     .|:.
 Frog   261 RVTKEEFYEAFCELCTRPEVYFLLVQISKNK-EYLDANDLMLFLESEQ---GMTQV-----TEEM 316

  Fly   274 CTEIINDYELDEEKKKNVQMSLDGFKRYLMSDENAPVFLDRLD-----FYMEMDQPLAHYYINSS 333
            |.:||..|||.:|......:::|||.:||:|.|     .|..|     ...:|.|||:|||||||
 Frog   317 CLDIIQKYELSQEGCLKGFLTIDGFTQYLVSHE-----CDVFDPVHKKVCQDMAQPLSHYYINSS 376

  Fly   334 HNTYLSGRQIGGKSSVEMYRQTLLAGCRCVELDCWNGKGEDEEPIVTHGHAYCTEILFKDCIQAI 398
            |||||...|..|.:.:..|.:.|...||.:|||.  ..|.|.|||:.:.::..:.:.|::.|:.|
 Frog   377 HNTYLIEDQFRGPADINGYVRALKLSCRSIELDV--SDGPDNEPIICNRNSMTSSLAFRNVIEVI 439

  Fly   399 ADCAFVSSEYPVILSFENHCNRAQQYKLAKYCDDFFGDLLLKE-PLPDHPLDPGLPLPPPCKLKR 462
            ...||:|||:|:||...|||:..||..:.::....||..|..| ||   ||:..||.|.  |||:
 Frog   440 NKYAFISSEFPLILCIGNHCSVQQQKVMVQHIKKIFGSKLFTERPL---PLESYLPSPE--KLKK 499

  Fly   463 KILIKNKRMKPEVEKVELELWLKGELKTDDDPEEDASAGKPPEAAAAPAPAPEAAAAAEGAAEGG 527
            ||::|.|::..:.:.:|      ||: ||:|.|.:.|
 Frog   500 KIIVKGKKLPSDYDLLE------GEV-TDEDEEAEMS---------------------------- 529

  Fly   528 GGAEAEAAAANYSGS--TTNVHPWLSSMVNYAQPIKFQGFDKAIEKNIAHNMSSFAESAGMNYLK 590
                 ...:.:|.|.  ...:...||.:|:..:.::::.||..::......:.||:||.......
 Frog   530 -----RRMSEDYFGEQRLITLCKELSDLVSICKSVQYRDFDVTMKSQNYGEICSFSESQASRIAN 589

  Fly   591 QSSIDFVNYNKRQMSRIYPKGTRADSSNYMPQVFWNAGCQMVSLNFQSSDLPMQLNQGKFEYNGG 655
            :...|||||||:.:||:||...|.||||..||.|||.|||:|::|:|:....|.||...|..|||
 Frog   590 EYPEDFVNYNKKFLSRVYPSPMRIDSSNLNPQDFWNCGCQIVAMNYQTPGPMMDLNIAWFMQNGG 654

  Fly   656 CGYLLKPDFMRRADKDFDPFADAPVDGVIAAQCSVKVIAGQFLSDKK--------VGTYVEVDMF 712
            |||:|:|..||.....|.......|.||......:|:|:||.....|        :..|:.:::.
 Frog   655 CGYVLRPSIMRDEISYFSANTKGMVPGVSPQVLHIKIISGQNFPKPKGACAKGDVIDPYICIEIH 719

  Fly   713 GLPSDTVKKEFRTRLVANNGLNPVYNEDPFVFRKVVLPDLAVLRFGVYEE---SGKILGQRILPL 774
            |:|:|..  |.||:.|..||.||:::|. |.| ::.||:||::||.|.::   ..:.:||..:|:
 Frog   720 GIPADCA--EQRTKTVQQNGDNPIFDES-FEF-QINLPELAMVRFMVLDDDYIGDEFIGQYTIPV 780

  Fly   775 DGLQAGYRHVSLRTEANFPMSLPMLFVNIELKIYVPDGFEDFMAMLSDPRGFAGAAKQQNEQMKA 839
            |.||.|||||.||:.....:....|||::
 Frog   781 DCLQPGYRHVPLRSFVGDTLEHAKLFVHV------------------------------------ 809

  Fly   840 LGIEEQSGGAARDAGKAKEEEKKEPPLVFEPVTLESLRQEKGFQ-KVGKKQIKELDTLRKKHAKE 903
             .|..:.||     |||                     |:||.. ::|||            |:|
 Frog   810 -AITNRGGG-----GKA---------------------QKKGLSARIGKK------------ARE 835

  Fly   904 RTSVQKTQNAAIDKLIKGKSKDDIRNDANIKNSINDQTKQWTDMIARHRKEEWDMLRQHVQDSQD 968
            .|.::.|....:|.:.|                           :|.|...|...:|:::|::..
 Frog   836 YTMLRNTGLKTVDDIFK---------------------------LAIHPLREASDVRENMQNALV 873

  Fly   969 AMKALMLTVQAAQIKQ--------LEDRHARDIKDLNAK---------------QAKMSADTAKE 1010
            ::|.|.....:|.:||        |.:..:..:..||.|               |.|:.......
 Frog   874 SLKELCGVPTSASLKQCILSLATRLVNSDSTPLVFLNMKDNYPYLEPVGAIPDVQKKLLTAYELM 938

  Fly  1011 VQNDKTL--KTKNEKDRRLREKRQNNVKRFMEEKKQIGVKQGRAMEKLKLAHSKQIEEFSTDVQK 1073
            :|..:||  ......|:.|  :.|.....|.||...:|.|:|....||    :|.||.|:.:|..
 Frog   939 IQESRTLFESADTIHDKIL--QCQKTGMEFHEELHSLGTKEGIKGRKL----NKAIESFAWNVTV 997

  Fly  1074 L 1074
            |
 Frog   998 L 998

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
norpA	NP_001014720.1	PH_PLC_beta	17..149	CDD:270167	23/126 (18%)
		PLN02952	224..786	CDD:178538	191/580 (33%)
		EF-hand_like	227..318	CDD:286375	24/95 (25%)
		PI-PLCc_beta	318..653	CDD:176533	114/337 (34%)
		C2_PLC_like	689..806	CDD:175974	43/127 (34%)
		DUF1154	866..908	CDD:284131	9/42 (21%)
		Mer2	<887..1003	CDD:286200	23/138 (17%)
plcl1	XP_012826838.2	PH_PLC_eta	79..187	CDD:270170	21/110 (19%)
		EFh_PRIP1	207..349	CDD:320052	37/156 (24%)
		PI-PLCc_PRIP_metazoa	361..652	CDD:176539	114/337 (34%)
		C2_PLC_like	684..812	CDD:175974	43/168 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D368239at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920