Protein Alignment NO66 and RIOX2

DIOPT Version :9

• Sequence 1: NP_572160.1
• Gene: NO66 / 31374
• FlyBaseID: FBgn0266570
• Length: 653
• Species: Drosophila melanogaster
• Sequence 2: NP_001035998.1
• Gene: RIOX2 / 84864
• HGNCID: 19441
• Length: 465
• Species: Homo sapiens
• Alignment Length: 512
• Identity: 139/512 - (27%)
• Similarity: 227/512 - (44%)
• Gaps: 101/512 - (19%)

  Fly   183 KAEPT----EEGNNNNDEKETETIETHKADSVEEGRRVLQWILFPVQTKVFFKDFWEHTACLVQR 243
            ||:||    |||.....:.:.|......|.:.:....:.:.::.|::|:.|||:|||....|:||
Human     4 KAKPTGSGKEEGPAPCKQMKLEAAGGPSALNFDSPSSLFESLISPIKTETFFKEFWEQKPLLIQR 68

  Fly   244 SNP---KYFQSMISFKMLD-EILIRHHLDFTVNVDVTTYKNGKRETLNPEGRA-LPPAVWGFYSD 303
            .:|   .|:.|:  ||:.| :.|....:.:..:|:|....|||::.||.:|:| .......|...
Human    69 DDPALATYYGSL--FKLTDLKSLCSRGMYYGRDVNVCRCVNGKKKVLNKDGKAHFLQLRKDFDQK 131

  Fly   304 GCSIRLLNPSTYLIRLRQVCTVLQEFFHCKVGANLYLTPPNSQGFAPHYDDIEAFVIQVEGRKRW 368
            ..:|:...|..:...|.::...|:.:|...||:|:|:||..|||..|||||:|.|::|:||.|.|
Human   132 RATIQFHQPQRFKDELWRIQEKLECYFGSLVGSNVYITPAGSQGLPPHYDDVEVFILQLEGEKHW 196

  Fly   369 LLYEPPKKADQLARISSGNYD---QEQLGKPIIDEVLSAGDVLYFPRGAVHQAITEE-QQHSLHI 429
            .||.|   ...|||    .|.   :|::|:|:.:.:|..||:||||||.:|||.|.. ..||.|:
Human   197 RLYHP---TVPLAR----EYSVEAEERIGRPVHEFMLKPGDLLYFPRGTIHQADTPAGLAHSTHV 254

  Fly   430 TLSVYQQQAYAN-LLETLMPMVLKKAVDRSVALRRGLPLHTFQVLGNAYKGNDCGSRKQLVENVQ 493
            |:|.||..::.: ||:|:..:|...|.: .|.||.|:|                   :||:..|:
Human   255 TISTYQNNSWGDFLLDTISGLVFDTAKE-DVELRTGIP-------------------RQLLLQVE 299

  Fly   494 ------KLVTNYLMPSEDDIDEAVD----QMAKKFQHEALPPIVL-PSEEVRTVHGARSDADEQG 547
                  :.::.:|....|.::...:    .|.|.|....|||... ...|:.|..|
Human   300 STTVATRRLSGFLRTLADRLEGTKELLSSDMKKDFIMHRLPPYSAGDGAELSTPGG--------- 355

  Fly   548 NCVCDYKFNKKTSVRLLRAN---ILRLVTESDGS-------VRIYHHVDNGLDYCKYEPYFMEIL 602
                  |..:..||..|:..   :|.::.:.|.|       |.|||.:.|     ..|.:.|
Human   356 ------KLPRLDSVVRLQFKDHIVLTVLPDQDQSDEAQEKMVYIYHSLKN-----SRETHMM--- 406

  Fly   603 PEEAKAVELLISAYPF-------------YLTIDQLPLESSARKIEVATALWEHGLL 646
             ...:..|.....:|.             .:::..|.|.:...|..:..:||...|:
Human   407 -GNEEETEFHGLRFPLSHLDALKQIWNSPAISVKDLKLTTDEEKESLVLSLWTECLI 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NO66	NP_572160.1	cupin_like	229..534	CDD:304367	104/325 (32%)
RIOX2	NP_001035998.1	Cupin_4	52..364	CDD:400389	108/355 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159485
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3706
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5745
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D256684at33208
OrthoFinder	1	1.000	-	-		FOG0003095
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	7	6.660