Protein Alignment NO66 and RIOX1

DIOPT Version :9

• Sequence 1: NP_572160.1
• Gene: NO66 / 31374
• FlyBaseID: FBgn0266570
• Length: 653
• Species: Drosophila melanogaster
• Sequence 2: NP_078920.2
• Gene: RIOX1 / 79697
• HGNCID: 20968
• Length: 641
• Species: Homo sapiens
• Alignment Length: 607
• Identity: 213/607 - (35%)
• Similarity: 309/607 - (50%)
• Gaps: 64/607 - (10%)

  Fly    67 DDAGPSTSKKTQSGSAAAAKTADRKRRLQAEADANNNDTGKAGKLTKESEATQGARATKRKQARS 131
            ||.|.:.     .|.||.|...|..||         ...|..|. .:..||:..||:.:...||
Human    73 DDLGDAL-----PGGAAVAAVPDAARR---------EPYGHLGP-AELLEASPAARSLQTPSAR- 121

  Fly   132 LGLERTSPIQVNGAALACPLVRKSLPPGEANSCPQPP------------KKDPAAVNSLVKIIKA 184
                               ||..|.||......|..|            .:..|||.|......|
Human   122 -------------------LVPASAPPARLVEVPAAPVRVVETSALLCTAQHLAAVQSSGAPATA 167

  Fly   185 EPTEEGNNNNDEKETETIETHKAD------SVEEGRRVLQWILFPVQTKVFFKDFWEHTACLVQR 243
            ...:..|...:......:....|:      |.....|:.:|::.|:....|::..||..|.||:|
Human   168 SGPQVDNTGGEPAWDSPLRRVLAELNRIPSSRRRAARLFEWLIAPMPPDHFYRRLWEREAVLVRR 232

  Fly   244 SNPKYFQSMISFKMLDEILIRHHLDFTVNVDVTTYKNGKRETLNPEGRALPPAVWGFYSDGCSIR 308
            .:..|:|.:.|...||.:|....:.|..::|...|.||:||||||.|||||.|.|..|..|||:|
Human   233 QDHTYYQGLFSTADLDSMLRNEEVQFGQHLDAARYINGRRETLNPPGRALPAAAWSLYQAGCSLR 297

  Fly   309 LLNPSTYLIRLRQVCTVLQEFFHCKVGANLYLTPPNSQGFAPHYDDIEAFVIQVEGRKRWLLYEP 373
            ||.|..:...:.|...||||.|....|:|:|||||||||||||||||||||:|:||||.|.:|.|
Human   298 LLCPQAFSTTVWQFLAVLQEQFGSMAGSNVYLTPPNSQGFAPHYDDIEAFVLQLEGRKLWRVYRP 362

  Fly   374 PKKADQLARISSGNYDQEQLGKPIIDEVLSAGDVLYFPRGAVHQAITEEQQHSLHITLSVYQQQA 438
            ....::||..||.|:.|:.||:|::..||..||:||||||.:|||..::..||||:|||.||:..
Human   363 RVPTEELALTSSPNFSQDDLGEPVLQTVLEPGDLLYFPRGFIHQAECQDGVHSLHLTLSTYQRNT 427

  Fly   439 YANLLETLMPMVLKKAVDRSVALRRGLPLHTFQVLGNAYKGNDCGSRKQLVENVQKLVT--NYLM 501
            :.:.||.::|:.::.|::.:|..|||||......:|..:..:....|...:|.|:.||.  .:..
Human   428 WGDFLEAILPLAVQAAMEENVEFRRGLPRDFMDYMGAQHSDSKDPRRTAFMEKVRVLVARLGHFA 492

  Fly   502 PSEDDIDEAVDQMAKKFQHEALPPIVLPSEEVRTVHG--ARSDADEQGNCVCDYKFNKKTSVRLL 564
            |    :|...||.||.|.|::|||::...|...:|:|  .|.:|.|..|  ...:...:|.|.:|
Human   493 P----VDAVADQRAKDFIHDSLPPVLTDRERALSVYGLPIRWEAGEPVN--VGAQLTTETEVHML 551

  Fly   565 RANILRLVTESDGSVRIYHHVDNGLDYCKYEPYFMEILPEEAKAVELLISAYPFYLTIDQLPLES 629
            :..|.|||.|. |.:.:|:.|:|...|...||..:||.|::|.|:|||:.:||.::.:..||.:|
Human   552 QDGIARLVGEG-GHLFLYYTVENSRVYHLEEPKCLEIYPQQADAMELLLGSYPEFVRVGDLPCDS 615

  Fly   630 SARKIEVATALWEHGLLMTEKP 651
            ...::.:||.|::.|||:|:.|
Human   616 VEDQLSLATTLYDKGLLLTKMP 637

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NO66	NP_572160.1	cupin_like	229..534	CDD:304367	135/306 (44%)
RIOX1	NP_078920.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..35
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	54..80		3/11 (27%)
		Cupin_4	215..557	CDD:285279	145/347 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159486
Domainoid	1	1.000	273	1.000	Domainoid score	I1799
eggNOG	1	0.900	-	-		E1_KOG3706
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11366
Inparanoid	1	1.050	346	1.000	Inparanoid score	I2318
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53843
OrthoDB	1	1.010	-	-		D256684at33208
OrthoFinder	1	1.000	-	-		FOG0003095
OrthoInspector	1	1.000	-	-		oto89419
orthoMCL	1	0.900	-	-		OOG6_105535
Panther	1	1.100	-	-	LDO	PTHR13096
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2682
SonicParanoid	1	1.000	-	-		X4581
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	15	14.840