Protein Alignment NO66 and Riox2

DIOPT Version :10

• Sequence 1: NP_572160.1
• Gene: NO66 / 31374
• FlyBaseID: FBgn0266570
• Length: 653
• Species: Drosophila melanogaster
• Sequence 2: NP_080186.3
• Gene: Riox2 / 67014
• MGIID: 1914264
• Length: 465
• Species: Mus musculus
• Alignment Length: 518
• Identity: 139/518 - (26%)
• Similarity: 227/518 - (43%)
• Gaps: 113/518 - (21%)

  Fly   183 KAEPTEEGNNNND---------EKETETIETHKADSVEEGRRVLQWILFPVQTKVFFKDFWEHTA 238
            |.:||  |:.|.:         |:..||:.....||...   ..:.::.|::.:.|||:|||...
Mouse     4 KVQPT--GDENEEASVPCKRVKEELPETLSVLNFDSPSS---FFESLISPIKVETFFKEFWEQKP 63

  Fly   239 CLVQRSNP---KYFQSMISFKMLDEILIRHHLDFTVNVDVTTYKNGKRETLNPEGRA-LPPAVWG 299
            .|:||.:|   ||:||:.|...|.. |.:..:.:..:|:|....:||::.||.:||| .......
Mouse    64 LLIQRDDPVLAKYYQSLFSLSDLKR-LCKKGVYYGRDVNVCRSISGKKKVLNKDGRAHFLQLRKD 127

  Fly   300 FYSDGCSIRLLNPSTYLIRLRQVCTVLQEFFHCKVGANLYLTPPNSQGFAPHYDDIEAFVIQVEG 364
            |.....:|:...|..|...|.::...|:.:|...||:|:|:||..|||..|||||:|.|::|:||
Mouse   128 FDQKRATIQFHQPQRYKDELWRIQEKLECYFGSLVGSNVYMTPAGSQGLPPHYDDVEVFILQLEG 192

  Fly   365 RKRWLLYEPPKKADQLARISSGNYDQEQLGKPIIDEVLSAGDVLYFPRGAVHQAITEE-QQHSLH 428
            .|.|.||.|.........:.|    ::::|.|..|.:|..||:||||||.:|||.|.. ..:|:|
Mouse   193 TKHWRLYSPTVPLAHEYSVES----EDRIGTPTHDFLLKPGDLLYFPRGTIHQAETPSGLAYSIH 253

  Fly   429 ITLSVYQQQAYAN-LLETLMPMVLKKAVDRSVALRRGLPLHTFQVLGNAYKGNDCGSRKQLVE-- 490
            :|:|.||..::.: ||:::...|...|.: .||||.|:|                  |:.|:.
Mouse   254 LTISTYQNNSWGDCLLDSISGFVFDIAKE-DVALRSGMP------------------RRMLLNVE 299

  Fly   491 ---NVQKLVTNYLMPSEDDIDEAVD----QMAKKFQHEALPPIVLPSEEVRTVHGARSDADEQGN 548
               :|.:.::.:|....|.::...:    .|.|.|....|||.         ..|..::..:.|
Mouse   300 TPADVTRKLSGFLRTLADQLEGREELLSSDMKKDFVKHRLPPF---------FEGNGTETMDPG- 354

  Fly   549 CVCDYKFNKKTSVRLLRANILRL-----VTESDGS------------VRIYHHVDNGLDYCKYEP 596
                     |...||  .||:||     :..:.|.            |.|||.:.|...
Mouse   355 ---------KQLPRL--DNIIRLQFKDHIVLTVGPDKNPFDEAQQKVVYIYHSLKNVRQ------ 402

  Fly   597 YFMEILPEEAKAVELLISAYPFY-------------LTIDQLPLESSARKIEVATALWEHGLL 646
              |.::.||.:: |:....:|..             :.:..|.|::...|..:|.:||...|:
Mouse   403 --MHMIGEEEES-EIFGLRFPLSHVDALKQIWCGSPIRVKDLKLDTDEEKENLALSLWSESLI 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NO66	NP_572160.1	JmjC_2	308..441	CDD:480661	52/133 (39%)
Riox2	NP_080186.3	JmjC_2	136..261	CDD:462340	51/128 (40%)
		ROXA-like_wH	332..428	CDD:466663	25/125 (20%)