Protein Alignment NO66 and NO66

DIOPT Version :10

• Sequence 1: NP_572160.1
• Gene: NO66 / 31374
• FlyBaseID: FBgn0266570
• Length: 653
• Species: Drosophila melanogaster
• Sequence 2: XP_321123.5
• Gene: NO66 / 1281185
• VectorBaseID: AGAMI1_011556
• Length: 772
• Species: Anopheles gambiae
• Alignment Length: 728
• Identity: 264/728 - (36%)
• Similarity: 370/728 - (50%)
• Gaps: 105/728 - (14%)

  Fly     1 MKKATTSAAAKSQGNSKMQKNANNG--------------TAKDKKKPNLDKESNDSNSVSDMLAV 51
            |:.||.:.........|.:..|.||              |..:||.|...|:...|...|.....
Mosquito    60 METATATPGPPELVLPKDEPGAGNGVTPGGTTITTSTPLTGSNKKPPQKRKKPAASPQPSPSTKP 124

  Fly    52 TKDQEVHAFFSKLFDDDAGPSTSKKTQ-------SGSAAAAKTADRKRRLQAEADANNNDTGKAG 109
            .:|.|..|         |..||:...|       |..|..|....::::...|.......|...|
Mosquito   125 KQDSEPAA---------ADGSTTNGEQVRPVPEGSSQAEPAPVVKKQKKKHTEEGKQTTSTTPPG 180

  Fly   110 K------------------LTKESEATQGARATKRKQAR-------------------SLGLE-- 135
            |                  .:|:..|...|...|:|:|:                   :.|.|
Mosquito   181 KKQKGATGKHVRFHIKLYSASKQPTAATTAGIAKKKKAKQQQAVPGVVPEQQHKQQNGATGAEPK 245

  Fly   136 -----RTSPIQVNGAALACPLVRKSLPPGEANSCPQPPKKDPAAVNSLVKIIKAEPTEEGNNNND 195
                 :..|.:|||.|:..|......|...|:...|.||....|.:|         |..|..::.
Mosquito   246 KKASKKGRPAKVNGGAVGLPPTSVVTPLKRASQIKQEPKTPSRAAHS---------TIVGGTSSS 301

  Fly   196 EKETETIE-----THKADSVEEGRRVLQWILFP-VQTKVFFKDFWEHTACLVQRSNPKYFQSMIS 254
            .....|..     .|:.|||..||:...|::.| :....|.:..||....||||::..|:..::|
Mosquito   302 TTTPTTASPAGTALHELDSVTIGRQTFAWLIGPTISVDEFMRTHWERKPLLVQRNDRAYYAGLLS 366

  Fly   255 FKMLDEILIRHHLDFTVNVDVTTYKNGKRETLNPEGRALPPAVWGFYSDGCSIRLLNPSTYLIRL 319
            ..|:||:|..:::::|.|:|:|:|::|:|||.||:||.|||.:|.||..|||:|:|||.|||..:
Mosquito   367 RAMIDEMLRTNNIEYTKNIDITSYRDGQRETHNPDGRVLPPDLWHFYDAGCSVRMLNPQTYLRSV 431

  Fly   320 RQVCTVLQEFFHCKVGANLYLTPPNSQGFAPHYDDIEAFVIQVEGRKRWLLYEPPKKADQLARIS 384
            .::...|||:|||..|||.|||||.|||||||||||||||:|:||||||.||.|.:..:.|||:|
Mosquito   432 YELNVKLQEYFHCMTGANFYLTPPGSQGFAPHYDDIEAFVLQIEGRKRWRLYGPRQPQEVLARVS 496

  Fly   385 SGNYDQEQL-GKPIIDEVLSAGDVLYFPRGAVHQAITEEQQHSLHITLSVYQQQAYANLLETLMP 448
            |.|..|::| |.||:|.||.|||:||||||.:|||.|....||||||:||||:..:|:|.|.::|
Mosquito   497 SENLRQDELAGPPIVDVVLEAGDLLYFPRGCIHQAATVPGAHSLHITVSVYQRNCWADLFEQMLP 561

  Fly   449 MVLKKAVDRSVALRRGLPLHTFQVLGNAYKGNDCGSRKQLVENVQKLVTNYLMPSEDDIDEAVDQ 513
            :.|..|.|....||.||||...|..|..:.......|::|:..::.:.....  |:..||.||||
Mosquito   562 IALATAADTEPQLREGLPLDLHQHFGIVHSDGISADRRRLIVRIRAMFDKLF--SDAAIDAAVDQ 624

  Fly   514 MAKKFQHEALPPIVLPSEEVRTVHGA-----RSDADEQGNCVCDYKFNKKTSVRLLRANILRLVT 573
            :||:|||:||||:|...|...||:|.     |.|    |...|....:.::||||||.||||||:
Mosquito   625 LAKRFQHDALPPLVDFGEWDDTVYGGGNYEFRPD----GTVRCARPIDDRSSVRLLRRNILRLVS 685

  Fly   574 ESDGSVRIYHHVDNGLDYCKYEPYFMEILPEEAKAVELLISAYPFYLTIDQLPLESSARKIEVAT 638
            |.: .:|||:|.||..:|.:||..|:|:..|.|..|||||..||.|:.:..||:|.   ::|...
Mosquito   686 EEE-KLRIYYHTDNSREYHQYEANFLELDHETALGVELLIKMYPRYVLVSSLPVED---RLEFIR 746

  Fly   639 ALWEHGLLMTEKP 651
            :|||.||::..:|
Mosquito   747 SLWEKGLIVCRRP 759

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NO66	NP_572160.1	JmjC_2	308..441	CDD:480661	83/133 (62%)
NO66	XP_321123.5	None