Protein Alignment mei-9 and Mus81

DIOPT Version :9

• Sequence 1: NP_001284859.1
• Gene: mei-9 / 31373
• FlyBaseID: FBgn0002707
• Length: 961
• Species: Drosophila melanogaster
• Sequence 2: NP_082153.3
• Gene: Mus81 / 71711
• MGIID: 1918961
• Length: 551
• Species: Mus musculus
• Alignment Length: 584
• Identity: 116/584 - (19%)
• Similarity: 179/584 - (30%)
• Gaps: 241/584 - (41%)

  Fly   356 AEQIFKLSRQRVFNGQQEFEPEP-CP-----KWQT--------------------LTDLLTKEIP 394
            ||.: :|.|:|         |.| ||     :|.|                    |..|....:|
Mouse     2 AEPV-RLGRKR---------PLPVCPNPLFVRWLTEWRDEAASRGRHTRFVFQKALRSLQRYPLP 56

  Fly   395 GDMRRSRRSEQQPKVLILCQDARTC----HQLKQYLTQGG-----------------PRFLLQQA 438
                  .||.::.|:|....| |.|    .:|||:|..||                 |    :|.
Mouse    57 ------LRSGKEAKILQHFGD-RLCRMLDEKLKQHLASGGDHAPSSPSGKKGASKGPP----EQV 110

  Fly   439 LQHEVPV------GKLSDNY--AKESQTRS------APPKNVSSNKELRREE------------V 477
            ....:||      |..|..|  |:.|..|.      ....|...:..|.:||            |
Mouse   111 QDSSMPVPTQPQAGSTSVGYWPAQNSGAREILLQLYREHLNSDGHSFLTKEELLQKCAQKTPRVV 175

  Fly   478 SGSQPPLAGMD------------------------ELAQLLSESE----------TEGQHFEESY 508
            .||..|...:.                        ||||.|:|:|          .|..|.|:|.
Mouse   176 PGSSKPWPALRSLLHRNLILGTHRPARYALTPEGLELAQKLAEAEGLSTRHAGFRPEEHHGEDSA 240

  Fly   509 M------------LTMTQPVEVGPA------AIDI--------KPD-----PDVSIFETIPELEQ 542
            :            ....:|:|:.|:      .:||        :|:     ..:.:..|:.:|..
Mouse   241 VPEALSEPGTTEGAVQQRPLELRPSEYRVLLCVDIGETRGAGHRPEMLRELQRLRVPHTVRKLHV 305

  Fly   543 FD-VTAALASVPHQPYICLQTFKTEREGSMALEHMLEQLQPHYVVMYNMNVTAIRQLE-----VF 601
            .| |..|..:.|..|         ||.|.:.|:|::|:                ::|:     :.
Mouse   306 GDFVWVAQETRPRDP---------ERPGELVLDHIVER----------------KRLDDLCSSII 345

  Fly   602 EARRRLPPADRMK-------VYFL-----IHARTVEEQAYLTSLRREKAAFEFIIDTKSKMVIPK 654
            :.|.| ....|:|       ||.:     :|..::.|...|.::...:     :||   ...:.:
Mouse   346 DGRFR-EQKFRLKRCGLGHRVYLVEEHGSVHNLSLPESTLLQAVTNTQ-----VID---GFFVKR 401

  Fly   655 YQDGKTDEAFLLLKTYDDEP--TDENAKSRQAG--GQAPQATKETPKVIVDMREFRSDLPC---- 711
            ..|.|....:|.|.|...|.  .....:||..|  |.|....|.:...:..:..| ||...
Mouse   402 TMDIKESAGYLALLTKGLERLYQGHTLRSRPWGAPGAAESEAKPSTNPLCSLLTF-SDFNAEAVK 465

  Fly   712 -------------LIHKRGLEVLPLTITIGDYILTP-------DICVERKSISDLIGSLNSGRL 755
                         |:..|||........:..| .||       |.|...|....|:.::..|||
Mouse   466 NKAQSVREVFARQLMQVRGLSGEKAAAVVDRY-STPASLLAAYDACATAKEQEMLLSTIKCGRL 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mei-9	NP_001284859.1	rad1	122..923	CDD:273163	116/584 (20%)
		ERCC4	700..832	CDD:280828	17/80 (21%)
Mus81	NP_082153.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	84..131		9/50 (18%)
		Interaction with BLM. /evidence=ECO:0000250	125..244		24/118 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	229..259		4/29 (14%)
		MUS81	248..515	CDD:224859	55/302 (18%)
		ERCC4	273..415	CDD:280828	31/175 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1948
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900