Protein Alignment mei-9 and xpf-1

DIOPT Version :10

• Sequence 1: NP_525068.1
• Gene: mei-9 / 31373
• FlyBaseID: FBgn0002707
• Length: 961
• Species: Drosophila melanogaster
• Sequence 2: NP_496498.1
• Gene: xpf-1 / 174793
• WormBaseID: WBGene00008140
• Length: 935
• Species: Caenorhabditis elegans
• Alignment Length: 980
• Identity: 251/980 - (25%)
• Similarity: 449/980 - (45%)
• Gaps: 175/980 - (17%)

  Fly    36 EEYLKRKNMVLLDYEKQMFLDLVEADGLLVCAKGLSYDRVVISILKAYSDSGNLVLVINSSDWEE 100
            :.:..:..:.||:||:......:.|..|.|.|.||..:|:.:..|..:||...|.||:|:::.:|
 Worm    14 DSFGNKDGLELLEYERATLAKTLPASVLFVVANGLGLERLFLEHLILFSDRRLLALVLNTNEHDE 78

  Fly   101 QYYKSKI-------EPKYVHEVASTATERERVYLEGGLQFISTRILVVDLLKQRIPIELISGIIV 158
            .|:.||:       :||.::...| ..:|:.:|||||:||.|:|:|:||||:.|||.:.|:.|.|
 Worm    79 SYFVSKLKEHNVECDPKVINSEVS-IKDRQSIYLEGGVQFCSSRVLLVDLLQNRIPTDRIAAIFV 142

  Fly   159 LRAHTIIESCQEAFALRLFRQKNKTGFVKAFSSSPEAFTIGYSHVERTMRNLFVKHLYIWPRFHE 223
            .|||..:.:.|::|.|||:|:|...|.||||:..|.:.: ....::|.:..|:::|:.:.|||..
 Worm   143 YRAHQTLNAFQDSFILRLYREKKPDGTVKAFTDFPNSLS-SLGQLQRLVDRLYIRHVELMPRFSS 206

  Fly   224 SVRTVLQPWKIQSIEMHVPISQNITSIQSHILEIMNFLVQEIKRINRT------VDMEAVTVENC 282
            .:.:.|..:::::....|.:...:..:...|:|.:...|::::..:.:      .:.|.:.|...
 Worm   207 IIESELNRYQLKTAIFSVDVPTPLRRVHRTIIEFIKVCVRDLRTCSTSGKQTDEQNEEMIHVPWA 271

  Fly   283 VTKSFHKILQAQLDCIWHQLNSQTKLIVADLKILRSLMISTMYHDAVSAYAFMKRYRSTEYAL-S 346
            .|:     |:.:|......::.:.:.::.|:..||.::..:...|..:..:.::..::....| .
 Worm   272 ATR-----LEKRLHDRRGHISEKQQRLLNDVASLREILQLSENMDVATVLSRLQVLKNDRTVLEE 331

  Fly   347 NSGWTLLDAAEQIFK--LSRQRVFNGQQEFEPEPCP-KWQTLTDLL--TKEIPGDMRRSRRSEQQ 406
            :|||.|..:..:|.:  |:...|.||:.:::....| ||..|:::|  .|.:|  :.:..|....
 Worm   332 HSGWLLSPSFNRIMEDLLTIAGVTNGKADYKKFATPAKWTVLSEILREIKMLP--VEKKDRGNDS 394

  Fly   407 PKVLILCQDARTCHQLKQYLTQGGPRFLLQQALQHEVPVGKLSDNYAKESQTRSAPPKNVSSNKE 471
            |.||::........|:...:..|               :.|:     |....|....|   |.:|
 Worm   395 PSVLVITSSEDLSRQVTDVVRYG---------------INKM-----KWMTWRQLGYK---STQE 436

  Fly   472 LRREEVSGSQPPLAGMDELAQLL-----SESETE-------------------GQHFEE-----S 507
            :..:|      ||...|.::||:     .||::|                   .:|.||     |
 Worm   437 MPEDE------PLWDPDTISQLMRSSVDGESKSEVIANVQKTQKTTARAAQKRRKHAEELSGFSS 495

  Fly   508 YMLTMTQPVEVG-------PAAIDIKPDPDVSIFETIPELEQF-DVTAALASVPHQPYICLQTFK 564
            .....|..::.|       .:..:.....:.:.:|...|:|:. ::|..:..:  :..:.:.|.:
 Worm   496 DHRVQTNLIQFGILQYKRRKSGNEASTSQETTEWEVKEEMEEIEEITKNIGDL--EAELVVSTTR 558

  Fly   565 TEREGSMALEHMLEQLQPHYVVMYNMNVTAIRQLEVFEARRRLPPADRMKVYFLIHARTVEEQAY 629
             |||....|: :||..:|..:|:|.|::..:||:|::   |...|...:.||:|.:..:.||..|
 Worm   559 -ERERYTLLK-LLETKKPRAIVLYTMSLQTLRQIEIY---RSTNPNRSLHVYWLQYTESTEESRY 618

  Fly   630 LTSLRREKAAFEFIIDTKSKMVIPK-YQDGKTDEAFLLLKTYDD---------EPTDENAKSRQA 684
            |.|:.||..:||.:|..:..::|.: :...:.|...|.:.|.|.         :|.|:
 Worm   619 LESINRETMSFELLIREQGTLLISREFNVDREDAPRLKISTRDGGGARRDGAVDPRDQ------- 676

  Fly   685 GGQAPQATKETPKVIVDMREFRSDLPCLIHKRGLEVLPLTITIGDYILTPDICVERKSISDLIGS 749
              ..|:...|.||:|||||||.|:||.:::.:|..|:..||.||||||:|:|.:|||::.||..|
 Worm   677 --MDPEEELERPKIIVDMREFNSELPTVLYTKGYNVVATTIEIGDYILSPNIAIERKALDDLTQS 739

  Fly   750 LNSGRLYNQCVQMQRHYAKPILLIEFDQNKPFHLQGKFMLSQQTSMANADIVQKLQLLTLHF--- 811
            |.|||::.|..||..||...:||||  .|:.|          :|.:.|....|  ..|:.|.
 Worm   740 LQSGRVFKQIEQMLEHYDCTVLLIE--SNRKF----------ETKIVNGGPFQ--GELSRHCREI 790

  Fly   812 -----------PKLRLIWSPSPYATAQLFEELKLGKPEPDPQTAAALGSDE-------------- 851
                       ||:|.:|:.||..:|:.|.||||..||||...|.:|.:|:
 Worm   791 RSIFCSLIWANPKMRCVWTISPTNSAEFFSELKLSAPEPDVDRAISLKADQVECSSQELTDSEAS 855

  Fly   852 ----PTAGEQLHFNSGIYDFLLRLPGVHTRNIHGLLRKGGSLRQLLLRSQKELEELLQSQESAKL 912
                ...|::...|..:...|.::.|:.....|.||...         |.|.|.:|.....:|..
 Worm   856 TSTKAKKGKKWKPNPTVIRTLTQIFGIKASEAHNLLANS---------SIKTLADLFSLNITASH 911

  Fly   913 LYDIL 917
            |.|.:
 Worm   912 LSDFI 916

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mei-9	NP_525068.1	rad1	122..923	CDD:273163	226/887 (25%)
xpf-1	NP_496498.1	rad1	106..855	CDD:273163	212/815 (26%)