Protein Alignment mei-9 and Ercc4l1

DIOPT Version :10

• Sequence 1: NP_525068.1
• Gene: mei-9 / 31373
• FlyBaseID: FBgn0002707
• Length: 961
• Species: Drosophila melanogaster
• Sequence 2: XP_063126086.1
• Gene: Ercc4l1 / 103693257
• RGDID: 1304845
• Length: 881
• Species: Rattus norvegicus
• Alignment Length: 931
• Identity: 349/931 - (37%)
• Similarity: 527/931 - (56%)
• Gaps: 117/931 - (12%)

  Fly    40 KRKNMV-LLDYEKQMFLDLVEADGLLVCAKGLSYDRVVISILKAYSDSGNLVLVINSSDWEEQYY 103
            :|::|. ||:||:|..|:|:::|||:|||:||..||::...|:.:.....||||:|:...||
  Rat     8 ERQSMAPLLEYERQQVLELLDSDGLVVCARGLGADRLLYLFLRLHCHPACLVLVLNTQPAEE--- 69

  Fly   104 KSKIEPKYVHEVASTATERERVYLEGGLQFISTRILVVDLLKQRIPIELISGIIVLRAHTIIESC 168
                             .|.|....||.....:|    |...:.:.   :.||:|.|||.|||||
  Rat    70 -----------------VRPRDGWTGGFGGHRSR----DWCGRNVK---LYGILVYRAHRIIESC 110

  Fly   169 QEAFALRLFRQKNKTGFVKAFSSSPEAFTIGYSHVERTMRNLFVKHLYIWPRFHESVRTVLQPWK 233
            ||||.|||||||||.||:|||:.:..||..|:.||||.|||||:|.||:|||||.:|.:.|:..|
  Rat   111 QEAFILRLFRQKNKLGFIKAFTDNAVAFDTGFCHVERVMRNLFMKKLYLWPRFHVAVNSFLEQHK 175

  Fly   234 IQSIEMHVPISQNITSIQSHILEIMNFLVQEIKRINRTVDMEAVTVENCVTKSFHKILQAQLDCI 298
            .:.:|:.|.::..:.:||:.||:::|..::|:|..|.::::|.:::||.:.|.|.|.:...||.:
  Rat   176 PEVVEIRVSMTLAMLAIQTAILDVLNACLKELKYHNLSLEVEDLSLENALGKPFDKTICHYLDPL 240

  Fly   299 WHQLNSQTKLIVADLKILRSLMISTMYHDAVSAYAFMKRYRSTEYAL-SNSGWTLLDAAEQIFKL 362
            ||||.::||.:|.||||||:|:.....:|.|:....::..|:||... .||||..|||:..:|..
  Rat   241 WHQLGAKTKSLVQDLKILRTLLQYLSQYDCVTFLNLLESLRATEKVFGQNSGWLFLDASTSMFVN 305

  Fly   363 SRQRVF--------------------NGQQEFEPEPCPKWQTLTDLLTKEIPGDMRRSRRSEQQP 407
            :|.||:                    ..::|...|..|||:.||::| |||..:.:.|.......
  Rat   306 ARARVYRVPDVKLSKKTKTSEKMAGTETKKELVLESNPKWEALTEVL-KEIETENKESEALGGPG 369

  Fly   408 KVLILCQDARTCHQLKQYLTQGGPRFLLQQALQHEVPVGKL------------------SDNYAK 454
            :|||...|.|||.||:.|||.|...|||:...:.....||.                  ||...|
  Rat   370 QVLICASDDRTCCQLRDYLTAGAEAFLLRLYRKTFEKDGKAEEVWVNFRKGDGPKRTMKSDKRPK 434

  Fly   455 ESQTRSAPPKNVSSNKELRREEVSGSQPPLAGMDELAQLLSESE---TEGQHFEESYMLTMTQPV 516
            ::|.:........:.|..::.|::           |.|:|..:|   .||...|:.:..|.:.|.
  Rat   435 DAQNKERASTKRGALKRKKKRELT-----------LTQVLGTAEEPPEEGAVEEDLHKQTGSSPE 488

  Fly   517 ----EVGPAAIDIKPDPDVSIFETIPELEQFDVTAALASVPHQPYICLQTFKTEREGSMALEHML 577
                |:...:.|:....|.:          :.:.....::.|....|...:        ||..:|
  Rat   489 VCGGEIQHESFDLNVSSDAA----------YGILKEPLTIIHPLLGCSDPY--------ALTRVL 535

  Fly   578 EQLQPHYVVMYNMNVTAIRQLEVFEARRRLPPADRMKVYFLIHARTVEEQAYLTSLRREKAAFEF 642
            .:::|.|||:|:..:|.:||||::.|.|   |...::|||.::..:.|||.|||:|.:||.|||.
  Rat   536 HEVEPRYVVLYDAELTFVRQLEIYRASR---PGKPLRVYFFVYGGSTEEQRYLTALCKEKEAFEK 597

  Fly   643 IIDTKSKMVIPKYQDGKTDEAFLLLKTYDDEPTDENAKSRQAGGQAPQATKETPKVIVDMREFRS 707
            :|..|:.||:|:.::|: ||..|.| .......|.:..:|:||||....|:  |.::||||||||
  Rat   598 LIREKASMVVPEEREGR-DETNLDL-ARGTAAMDTSTDTRKAGGQERNGTQ--PSIVVDMREFRS 658

  Fly   708 DLPCLIHKRGLEVLPLTITIGDYILTPDICVERKSISDLIGSLNSGRLYNQCVQMQRHYAKPILL 772
            :||.|||:||:::.|:|:.:|||||||::||||||:|||||||:|||||:||:.|.|:|.:|:||
  Rat   659 ELPSLIHRRGIDIEPVTLKVGDYILTPELCVERKSVSDLIGSLHSGRLYSQCLAMSRYYRRPVLL 723

  Fly   773 IEFDQNKPFHL--QGKFMLSQQTSMANADIVQKLQLLTLHFPKLRLIWSPSPYATAQLFEELKLG 835
            ||||.:|||.|  :|.|:    ..|:::|:..||.|||||||:|||:|.|||:|||:||||||..
  Rat   724 IEFDPSKPFSLAPRGAFV----QEMSSSDVSSKLTLLTLHFPRLRLLWCPSPHATAELFEELKQN 784

  Fly   836 KPEPDPQTAAALGSDEPTAGEQLHFNSGIYDFLLRLPGVHTRNIHGLLRKGGSLRQLLLRSQKEL 900
            ||:||..||.|:..|..|..|...:|.|..||:.::|||:.:|...|:.:..::.:|...|.:.|
  Rat   785 KPQPDAATAMAITEDSETLPESDRYNPGPQDFVQKMPGVNAKNCRSLMNQVQNIAELATLSLERL 849

  Fly   901 EELLQSQESAKLLYDILHVAH 921
            ..:|....:||.|:|.||.|:
  Rat   850 TGILGHSGNAKQLHDFLHTAY 870

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mei-9	NP_525068.1	rad1	122..923	CDD:273163	322/848 (38%)
Ercc4l1	XP_063126086.1	None