Protein Alignment mei-9 and ercc4

DIOPT Version :10

• Sequence 1: NP_525068.1
• Gene: mei-9 / 31373
• FlyBaseID: FBgn0002707
• Length: 961
• Species: Drosophila melanogaster
• Sequence 2: XP_002935520.3
• Gene: ercc4 / 100145552
• XenbaseID: XB-GENE-986815
• Length: 893
• Species: Xenopus tropicalis
• Alignment Length: 923
• Identity: 380/923 - (41%)
• Similarity: 562/923 - (60%)
• Gaps: 91/923 - (9%)

  Fly    46 LLDYEKQMFLDLVEADGLLVCAKGLSYDRVVISILKAYSDSGNLVLVINSSDWEEQYYKSKIE-- 108
            ||::|.|:||||...|||::.|:||..||::.:.||.|.|.||||||:|::..||:|...::.
 Frog     4 LLEHENQVFLDLFHEDGLVITARGLGIDRILQNFLKLYCDPGNLVLVLNTNTAEEEYLIDQLRSE 68

  Fly   109 -----PKYV-HEVASTATERERVYLEGGLQFISTRILVVDLLKQRIPIELISGIIVLRAHTIIES 167
                 |:.: :|||:  .||..||.:||:.|:::||||||.|..|||..||:||:|.:||.||||
 Frog    69 GVTHLPRIITNEVAT--GERYDVYTQGGVLFVTSRILVVDFLTDRIPANLITGILVYKAHKIIES 131

  Fly   168 CQEAFALRLFRQKNKTGFVKAFSSSPEAFTIGYSHVERTMRNLFVKHLYIWPRFHESVRTVLQPW 232
            |||||.|||:|||||.||:|||:.:|.||..|:..|||.|||||||.||:|||||.||.:.|...
 Frog   132 CQEAFILRLYRQKNKQGFIKAFTDNPVAFHTGFCQVERVMRNLFVKKLYLWPRFHVSVNSFLDKH 196

  Fly   233 KIQSIEMHVPISQNITSIQSHILEIMNFLVQEIKRINRTVDMEAVTVENCVTKSFHKILQAQLDC 297
            |.:.:|:||.::..:.:|||.||:|||..::|:||.|..:::|.:::||.:.|:|.|.::..||.
 Frog   197 KPEVVELHVSMTPAMLAIQSSILDIMNACLKELKRYNPALEVEDLSLENAIGKAFDKTIRHYLDP 261

  Fly   298 IWHQLNSQTKLIVADLKILRSLMISTMYHDAVSAYAFMKRYRSTEYAL-SNSGWTLLDAAEQIFK 361
            :||||.::||.:|.||||||:|:.....:|.|:....::..:::|.|. .||||..||::..:|.
 Frog   262 LWHQLGAKTKSLVQDLKILRTLLQYLSQYDCVTFLNLLESMKASEKAFGQNSGWLFLDSSTSMFV 326

  Fly   362 LSRQRVF--------------------NGQQEFEPEPCPKWQTLTDLLTKEIPGDMRRSRRSEQQ 406
            .:|.||:                    :|::|...|..|||:.|:::| |||..:.:.|......
 Frog   327 HARARVYHVPDSKAIKKSKQSDSNEKQDGKKELVLENNPKWEALSEVL-KEIEQENKNSEALGGP 390

  Fly   407 PKVLILCQDARTCHQLKQYLTQGGPRFLLQQALQHEVPVG---KLSDNYAKESQTRSAPPKNVSS 468
            .:|||...|.|||.||::|:..|....|  :.|.::. .|   |.|:.:.|..:..:|...|.|.
 Frog   391 GRVLICASDDRTCAQLREYIAVGAEALL--ERLYNKT-FGKDEKASEVWMKRRKAITAKGSNKSM 452

  Fly   469 NKELRREEVSGSQPPLAGMDELAQLLSESETEGQHFEESYMLTMTQPV------EVGPAAIDIKP 527
            ...|.::...|..         .|..:.::||         ||:||.:      |||..  |::.
 Frog   453 KTSLPKKPKEGKS---------KQKKNNTKTE---------LTLTQMIGKEEEDEVGKD--DVES 497

  Fly   528 DPDVSIFE---------TIPELEQFDVTAALASVPHQPYICLQTFKTEREGSMALEHMLEQLQPH 583
            ....|.||         .:|....:.:.....:|.|....|        ..|..|..:|.:::|.
 Frog   498 VSQESSFEEPKYEDLQLNLPSDSYYGILKEPLTVIHPLQGC--------SDSYGLTRVLHEIEPR 554

  Fly   584 YVVMYNMNVTAIRQLEVFEARRRLPPADRMKVYFLIHARTVEEQAYLTSLRREKAAFEFIIDTKS 648
            |||:|:..::.:||||::.|.::.|    ::|||||:..:.|||.||||||:||.|||.:|..|:
 Frog   555 YVVLYDSELSFVRQLEIYRASKQKP----LRVYFLIYGGSTEEQRYLTSLRKEKEAFEQLIREKA 615

  Fly   649 KMVIPKYQDGKTDEAFLLLKTYDDEPTDENAKSRQAGGQAPQATKETPKVIVDMREFRSDLPCLI 713
            .||||:.:||:.|....|.:  |...|.::|.:|:||||.....::|  :|||||||||:||.||
 Frog   616 SMVIPEERDGRDDTNLDLQR--DVTSTFDSADTRKAGGQVQNNVQQT--IIVDMREFRSELPSLI 676

  Fly   714 HKRGLEVLPLTITIGDYILTPDICVERKSISDLIGSLNSGRLYNQCVQMQRHYAKPILLIEFDQN 778
            |:||:::.|:|:.:|||||||||||||||:||||||||:||||.|||.|.|:|.:|:||||||.|
 Frog   677 HRRGIDIEPVTLEVGDYILTPDICVERKSVSDLIGSLNNGRLYTQCVSMCRYYKRPVLLIEFDPN 741

  Fly   779 KPFHLQGKFMLSQQTSMANADIVQKLQLLTLHFPKLRLIWSPSPYATAQLFEELKLGKPEPDPQT 843
            |||.|..|..:.|:.|:  .||..|:.|||||||:||::|.|||||||:||||||..:|:||..|
 Frog   742 KPFSLVSKNSIHQEISV--NDITSKIALLTLHFPRLRILWCPSPYATAELFEELKQNRPQPDSAT 804

  Fly   844 AAALGSDEPTAGEQLHFNSGIYDFLLRLPGVHTRNIHGLLRKGGSLRQLLLRSQKELEELLQSQE 908
            |.|:.:|..:..|...:|.|..||||::|||:.:|...:::...|:.:|...|.::|.|:|.:..
 Frog   805 AMAITADSESLPESEKYNPGPQDFLLKMPGVNAKNCRAIMKHVTSIAELTTLSLEKLTEILGNSN 869

  Fly   909 SAKLLYDILHVAH 921
            :||.||:.:..::
 Frog   870 NAKQLYEFMRTSY 882

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mei-9	NP_525068.1	rad1	122..923	CDD:273163	345/839 (41%)
ercc4	XP_002935520.3	rad1	86..884	CDD:273163	345/839 (41%)