DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12692 and kel-3

DIOPT Version :9

Sequence 1:	NP_001284857.1	Gene:	CG12692 / 31372	FlyBaseID:	FBgn0029703	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	NP_499784.2	Gene:	kel-3 / 176775	WormBaseID:	WBGene00002185	Length:	591	Species:	Caenorhabditis elegans

Alignment Length:	185	Identity:	51/185 - (27%)
Similarity:	81/185 - (43%)	Gaps:	44/185 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 LMTLLHTAVQLEMPALKALCYEQLCTDRFREETAFQVYLRALKYPQLEELRKLMLQRIGAAFLAV 193
            |:|.||.:..|   :::..| :.:|.:                    |::.::....|...|:||
Worm   146 LLTRLHPSNAL---SIREFC-KMMCVE--------------------EKITEMTDDYIQKHFMAV 186

  Fly   194 LGGDDFQRMPLEDVITMLQQDSLGVNSEMEVLVAIIRWLNCQSKCIDQATPLLMDCLRLTLLPLP 258
            ...:||:|:.|||.|.:|:.|.|.|:||.:|.||.:.||||.....:||..:| .|:||.||...
Worm   187 SKDEDFKRLSLEDAIELLRNDHLYVDSEEQVYVAAMEWLNCDVIRHEQAAKIL-PCVRLPLLSPT 250

  Fly   259 ILKRFWRCAMAPPVPDEPFMNAVRGNIHIRERISC--AITVVQMHHLHTSRREFL 311
            .|.                 :.|..|..|::.|.|  .|...:.:||...||..:
Worm   251 YLS-----------------SIVASNPIIKKDIPCRDLIDEAKDYHLLPDRRSLI 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12692	NP_001284857.1	BACK	162..265	CDD:285009	34/102 (33%)
kel-3	NP_499784.2	BTB_POZ	32..149	CDD:365784	1/2 (50%)
		PHA03098	51..568	CDD:222983	51/185 (28%)
		KELCH repeat	341..384	CDD:276965
		KELCH repeat	388..431	CDD:276965
		KELCH repeat	435..479	CDD:276965
		KELCH repeat	482..527	CDD:276965
		KELCH repeat	529..572	CDD:276965
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000