DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Muc4B and SPAPB1A10.13

DIOPT Version :9

Sequence 1:	NP_001284856.1	Gene:	Muc4B / 31368	FlyBaseID:	FBgn0052774	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_593527.1	Gene:	SPAPB1A10.13 / 2543439	PomBaseID:	SPAPB1A10.13	Length:	529	Species:	Schizosaccharomyces pombe

Alignment Length:	479	Identity:	107/479 - (22%)
Similarity:	178/479 - (37%)	Gaps:	97/479 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 SSNNQLQSANGTSLNNETITI-----------------NISEIIAAAEAASNTTESSSTTAPLST 81
            ||...|:..:|.:...|:.|:                 .||...|..|...||  .|:..|...:
pombe    59 SSFQDLKGMSGDAKEQESATLVHLTKGRAHPRSRRPPRQISIDSAKKEETKNT--GSTKAADTKS 121

  Fly    82 TTEATST---STASSATSTTVPASTTLTSSSTTQAGITTSTETSTSAQSTSTILADTSTTPNTPT 143
            :.|||.:   .|.|.:.::..|...|.:.:|||:...|...|...|:.:|..:.|.||...:..|
pombe   122 SVEATISPLKDTKSPSNASVFPIKPTESKTSTTKDSETAKEEDDASSSTTKAVEATTSKASSAHT 186

  Fly   144 ITTETSQSTVTQAPTTLQPSI-TTTQASTTTQLPTTSTSITITTTQASTTTTQTSTAAPSTTTTP 207
            .|..||.|...:..:|.:..: ...:..:|:.:|.:|.||.....||..|....|...|....|.
pombe   187 DTLATSASNSDRGASTPEMVVKAEKREGSTSPIPYSSLSIAERIKQAQNTPFLESKVLPQNNETS 251

  Fly   208 PSTTSTTQ--APTTTTLVQASTTTTLQPTTSTTPQSTSTTSTQAPTTTTTQSTSTATQPSTTTP- 269
            .......:  |.|...::||    .|||            :|.|..|.:.:.:.::.||..|.|
pombe   252 DEENVDVKPAAGTVKNVMQA----FLQP------------ATPAKDTASKEPSKSSQQPVRTKPR 300

  Fly   270 --QSPPTTTTQVSTTSTQPTTTTTPLP-TTTTTPLPTTTTTPLPT----TTTTPLPTTTSTPQPT 327
              |||  ...|.:..:......::||. :.:.:|....::|..||    ..:...|||:|    |
pombe   301 IAQSP--FLAQDAKENGGNVEVSSPLSFSASKSPAAVDSSTKTPTEQVNVVSKQAPTTSS----T 359

  Fly   328 TTTTPQPTTTTVPTTTTTTTQASTTSQSEITTTPAPTSSTEIGTTTTTAGSTTTSTT-------- 384
            :..:|.|..|..|:.......||..|: .:|......::..:|....:....|.|.:
pombe   360 SVISPDPLQTAAPSANVNEVIASLESK-VVTRRTGSGNNYRVGLRNVSGSERTKSLSKESPVEPE 423

  Fly   385 -------TTSTTPIAYTVYTMEPYPNIYGRSNEIAKPQRKLRKGRKGRRGRRPRRRTTP------ 436
                   |:|:||   |....|.:.|...:|::              :|.......|:|
pombe   424 KPALPDATSSSTP---TTENKESWTNQGIKSSQ--------------QRSANASPATSPSNQASI 471

  Fly   437 -APLT--SSTTTTTTTTVRTTLSG 457
             |..|  |||.::.:.|:.:..||
pombe   472 HASFTKESSTHSSPSFTLESLFSG 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Muc4B	NP_001284856.1	None
SPAPB1A10.13	NP_593527.1	PRK13108	<77..218	CDD:237284	33/142 (23%)
SPAPB1A10.13	NP_593527.1	ROM1	344..>527	CDD:227709	35/174 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000