DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fas2 and il1rapl1a

DIOPT Version :9

Sequence 1:	NP_001284854.1	Gene:	Fas2 / 31364	FlyBaseID:	FBgn0000635	Length:	885	Species:	Drosophila melanogaster
Sequence 2:	XP_021334418.1	Gene:	il1rapl1a / 568868	ZFINID:	ZDB-GENE-061013-249	Length:	1520	Species:	Danio rerio

Alignment Length:	311	Identity:	60/311 - (19%)
Similarity:	92/311 - (29%)	Gaps:	114/311 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   474 YDTNLKIVGT----------GPRSDLI---------VHPVTRQYYSGYKCIATNIHGTAEHDMQ- 518
            ||..::...|          |.|.|||         :|.:...  :.|..||:......:.|:|
Zfish   109 YDLEIQFFDTRCVAPCLVVPGQRDDLILGSNIIKHLIHELKNN--NDYWDIASRPDNKFDEDVQQ 171

  Fly   519 ----------LKEARVPDFVSEAKPSQLTATTMTFDIRGPSTELGLPILAYSVQYKEALNPDWS- 572
                      .|...|||.:...|.:|....              ||...:.|         |.
Zfish   172 FLSMFTGVERWKGDTVPDKIGTVKLTQAVVL--------------LPKHEHLV---------WGR 213

  Fly   573 TAYNRSWSPDSPYIVEGLRPQTEYSFRFAARNQVGLGNWG-----------VNQQQSTPRRSAPE 626
            ...|...||.|..|||....:.........|..|.|  ||           .|:..:..|.|...
Zfish   214 LPSNVPMSPGSTVIVEPTNSKAMPRDILVGRLVVPL--WGDRWVPMTVMNPTNKVITLKRNSKMA 276

  Fly   627 EPKP------------LHNPVQHDKEEPVVVSPYSDHFE---LRWGVPADNGEPIDRYQIKYCPG 676
            :..|            ||..:..:|.:....|..:||.:   |..|:     |.||
Zfish   277 DVFPCIASEDFEIFQGLHITLVENKSDDSCNSCAADHIDKNLLNLGL-----EEID--------- 327

  Fly   677 VKISGTWTELENSCNTVEVMETTSFEMTQLVG---NTYYRIELKAHNAIGY 724
                ..|:::.:.|.:         ::|||:.   :.:.:..|....|.||
Zfish   328 ----VNWSQISDDCKS---------QLTQLLADYQDIFSKHPLDCGEATGY 365

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fas2	NP_001284854.1	IG_like	39..133	CDD:214653
		IG_like	144..226	CDD:214653
		IGc2	152..209	CDD:197706
		I-set	230..319	CDD:254352
		IGc2	243..309	CDD:197706
		IG_like	330..424	CDD:214653
		IGc2	339..412	CDD:197706
		Ig	447..518	CDD:143165	13/62 (21%)
		fn3	534..611	CDD:278470	15/77 (19%)
		FN3	640..735	CDD:238020	17/91 (19%)
il1rapl1a	XP_021334418.1	retropepsin_like	46..137	CDD:133136	8/27 (30%)
		RT_LTR	403..579	CDD:238825
		RNase_HI_RT_Ty3	701..823	CDD:260006
		rve	1068..1176	CDD:307008
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000