DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fas2 and paplna

DIOPT Version :9

Sequence 1:	NP_001284854.1	Gene:	Fas2 / 31364	FlyBaseID:	FBgn0000635	Length:	885	Species:	Drosophila melanogaster
Sequence 2:	XP_005169942.1	Gene:	paplna / 562930	ZFINID:	ZDB-GENE-070815-4	Length:	1187	Species:	Danio rerio

Alignment Length:	304	Identity:	68/304 - (22%)
Similarity:	128/304 - (42%)	Gaps:	45/304 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 VGKPLILTCRPTVPEPSLVADLQWKDNRNNTILPKPNGRNQPPMYTETLPGESLALMITSLSVEM 110
            ||:.::|.||.| |.||....::|:  |:...:       .|..:.:.|.|   :|::..::::.
Zfish   846 VGQRVVLPCRVT-PPPSSAVLVEWR--RDGVPV-------DPTRHEQQLDG---SLLVGPITLQD 897

  Fly   111 GGKYYCTA-----------------SYANTEILEKGVTIKTYVAITWTNAPENQYPTL----GQD 154
            .|.:.|.|                 |..|...:.:..:.::|.:.:.:....:..|.:    ||.
Zfish   898 SGWFLCVATRDDKRDHRYIYLSVSGSSQNNAGISEVDSSQSYTSQSSSRFNIDYSPLVEARAGQT 962

  Fly   155 YVVMCE---VKADPNPTIDWLRNGDPIRTTNDKYVVQTNG-LLIRNVQESDEGIYTCRAAVIETG 215
            ..:.|.   |.|....||.|.|.|.|:.:.  ::...::| |:|:.:...|.|:|||  .|.:..
Zfish   963 AKLQCSVLPVSAIHAVTIHWSRAGQPLNSL--RHSQHSDGTLVIKQLTADDSGLYTC--TVTDAQ 1023

  Fly   216 ELLERTIRVEVFIQPEIISLPTNLEAVEGKPFAANCTARGKPVPEISWIRDATQLNVATADRFQV 280
            :..||.:::.|.....|...|.:::.|:|......|...|:.| .:.|.|:...:. ....|..|
Zfish  1024 KFEERQVQLRVLGDLRITKAPIDVDVVQGSTAQLACVVTGENV-NVGWSRNGVPVR-PDGHRVHV 1086

  Fly   281 NPQTGLVTISSVSQDDYGTYTCLAKNRAGVVDQKTKLNVLVRPQ 324
            :.. |.:.:::|...|.|||||.|......|....::.:...||
Zfish  1087 SAD-GTLILNNVQSVDEGTYTCNAYTGTLSVSAAAEIRLAKTPQ 1129

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fas2	NP_001284854.1	IG_like	39..133	CDD:214653	20/103 (19%)
		IG_like	144..226	CDD:214653	23/89 (26%)
		IGc2	152..209	CDD:197706	19/60 (32%)
		I-set	230..319	CDD:254352	21/88 (24%)
		IGc2	243..309	CDD:197706	17/65 (26%)
		IG_like	330..424	CDD:214653
		IGc2	339..412	CDD:197706
		Ig	447..518	CDD:143165
		fn3	534..611	CDD:278470
		FN3	640..735	CDD:238020
paplna	XP_005169942.1	TSP1	24..75	CDD:214559
		ADAM_spacer1	181..293	CDD:310520
		TSP1	303..356	CDD:214559
		TSP1	388..442	CDD:214559
		TSP1	449..498	CDD:214559
		TSP1	504..557	CDD:214559
		KU	720..771	CDD:238057
		Ig_3	839..906	CDD:316449	17/72 (24%)
		IGc2	960..1022	CDD:197706	20/65 (31%)
		I-set	1039..1121	CDD:333254	21/84 (25%)
		PLAC	1142..1173	CDD:312271
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900