DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fas2 and dpr13

DIOPT Version :9

Sequence 1:	NP_001284854.1	Gene:	Fas2 / 31364	FlyBaseID:	FBgn0000635	Length:	885	Species:	Drosophila melanogaster
Sequence 2:	NP_001033956.2	Gene:	dpr13 / 3885598	FlyBaseID:	FBgn0034286	Length:	419	Species:	Drosophila melanogaster

Alignment Length:	316	Identity:	65/316 - (20%)
Similarity:	108/316 - (34%)	Gaps:	108/316 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 TRAQSPILEIYPKQEVQRKPVGKPL-ILTCRPTVPEPSLVADLQWKDNRNNTILPKPNGRNQPPM 89
            |..|..:|:.:....:|.|....|. |...||...|..|.|        ||.|..........||
  Fly   119 THLQEAVLQTHSHSRIQAKDTAGPYPIPVHRPEPVENHLEA--------NNGIEGGMESLFGTPM 175

  Fly    90 Y--TETLPGESLALMITSLSVEMGGKYY--CTASYANTEILEKGVTIKTYVAITWTNAPENQYPT 150
            |  ||.         .|.::.::|...:  ||..:     :.:||       ::|....:....|
  Fly   176 YFGTEN---------STVVTTQIGATAHVPCTVHH-----IGEGV-------VSWIRKKDYHLLT 219

  Fly   151 LGQDYVVMCEVKADPNPTIDWLRNGDPIRTTNDKYVVQTNGLLIRNVQESDEGIYTCRA------ 209
            :|     :....:|...:...|::       ::.:.:|     |:.||..|.|:|.|:.
  Fly   220 VG-----LTTYSSDERFSATHLKH-------SEDWTLQ-----IKFVQLRDAGVYECQVSTHPPT 267

  Fly   210 ------AVIE-----TGELLE-----RTIRVEVFIQPEIISLPTNLEAVEGKPFAANCTARGKPV 258
                  :|:|     ||..:.     .|:|    :|..::.   |.||.|
  Fly   268 SIFLHLSVVEARAEITGPPIRYLTPGSTLR----LQCRVVQ---NTEASE--------------- 310

  Fly   259 PEISWIRDATQ--------LNVATADRFQVNPQTGLVTISSVSQDDYGTYTCLAKN 306
             .|.|..|...        :||:|...|    |:..:||....::..|.:||:|.|
  Fly   311 -YIFWYHDNRMINYDIDRGINVSTEPDF----QSSELTIQRTRREHSGNFTCVASN 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fas2	NP_001284854.1	IG_like	39..133	CDD:214653	23/98 (23%)
		IG_like	144..226	CDD:214653	18/103 (17%)
		IGc2	152..209	CDD:197706	11/56 (20%)
		I-set	230..319	CDD:254352	19/85 (22%)
		IGc2	243..309	CDD:197706	16/72 (22%)
		IG_like	330..424	CDD:214653
		IGc2	339..412	CDD:197706
		Ig	447..518	CDD:143165
		fn3	534..611	CDD:278470
		FN3	640..735	CDD:238020
dpr13	NP_001033956.2	V-set	180..276	CDD:284989	20/133 (15%)
		IG_like	182..262	CDD:214653	19/108 (18%)
		IG_like	285..362	CDD:214653	22/104 (21%)
		IGc2	292..361	CDD:197706	21/95 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900