DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fas2 and ImpL2

DIOPT Version :9

Sequence 1:	NP_001284854.1	Gene:	Fas2 / 31364	FlyBaseID:	FBgn0000635	Length:	885	Species:	Drosophila melanogaster
Sequence 2:	NP_728961.2	Gene:	ImpL2 / 38513	FlyBaseID:	FBgn0001257	Length:	267	Species:	Drosophila melanogaster

Alignment Length:	210	Identity:	49/210 - (23%)
Similarity:	77/210 - (36%)	Gaps:	43/210 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   236 PTNLEAVEGKPFAANCTARGKPVPEISWI---RDATQLNVATADRFQVNPQTGLVTISSVSQDDY 297
            ||.|:..:|......|...|..||.|.|:   ...::|:...:::......:.:|.:.|....|:
  Fly    65 PTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSHIIDH 129

  Fly   298 -----GTYTCLAKNRAGVVDQKTKLNVLVRPQIYELYNVTGARTKEIAIT--------------- 342
                 .||||:.:..:..:...|.::.....::.......||:...|..|
  Fly   130 VLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDLMGSNIQLP 194

  Fly   343 CRAKGRPAPAITFRRWGTQE--EYTNGQQDDDPRIILEPNFDEERGESTGTLRISNAERSDDGLY 405
            ||...||...||   |...|  |...|.:.   |::           :.|.|.||..:..|.|.|
  Fly   195 CRVHARPRAEIT---WLNNENKEIVQGHRH---RVL-----------ANGDLLISEIKWEDMGNY 242

  Fly   406 QCIARN-KGADAYKT 419
            :||||| .|.|...|
  Fly   243 KCIARNVVGKDTADT 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fas2	NP_001284854.1	IG_like	39..133	CDD:214653
		IG_like	144..226	CDD:214653
		IGc2	152..209	CDD:197706
		I-set	230..319	CDD:254352	19/90 (21%)
		IGc2	243..309	CDD:197706	15/73 (21%)
		IG_like	330..424	CDD:214653	30/108 (28%)
		IGc2	339..412	CDD:197706	25/90 (28%)
		Ig	447..518	CDD:143165
		fn3	534..611	CDD:278470
		FN3	640..735	CDD:238020
ImpL2	NP_728961.2	IGc2	187..251	CDD:197706	23/80 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900