DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fas2 and dpr20

DIOPT Version :9

Sequence 1:	NP_001284854.1	Gene:	Fas2 / 31364	FlyBaseID:	FBgn0000635	Length:	885	Species:	Drosophila melanogaster
Sequence 2:	NP_612066.1	Gene:	dpr20 / 38101	FlyBaseID:	FBgn0035170	Length:	525	Species:	Drosophila melanogaster

Alignment Length:	190	Identity:	39/190 - (20%)
Similarity:	74/190 - (38%)	Gaps:	44/190 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   152 GQDYVVMCEVKADPNPTIDWLR---------NGDPI--------RTTNDK-YVVQTN-----GLL 193
            |....:.|.:....:.|:.|:|         ||:.:        ..|.|| |.::..     .|.
  Fly   284 GSSIHLNCRISLLQDKTVSWVRHNTQDEGKDNGNALDLLTVGMHTYTGDKRYKMEFQYPNNWRLK 348

  Fly   194 IRNVQESDEGIYTCRAAVIETGELLERTIRVEVFIQ-PEIISLPTNLEAVEGKPF------AANC 251
            |.||::.||.||.|:   |.|..  .|.|::.:.:. |:::.:....:.::.|.:      ..:|
  Fly   349 ITNVKKDDEAIYECQ---ISTHP--PRVIQINLHVNAPKVMIVDEVGDPLQEKYYEIDSTLQLSC 408

  Fly   252 TARGKPVPE--ISWIR-------DATQLNVATADRFQVNPQTGLVTISSVSQDDYGTYTC 302
            ..|...:..  :.|..       |.|:..|:.......:.....::|:.:|:.|.|.|||
  Fly   409 VVRNVAMTSSVVFWKHMDNILNYDVTRGGVSVKTELMEDGANSTLSIAKISKTDSGNYTC 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fas2	NP_001284854.1	IG_like	39..133	CDD:214653
		IG_like	144..226	CDD:214653	24/96 (25%)
		IGc2	152..209	CDD:197706	20/79 (25%)
		I-set	230..319	CDD:254352	15/88 (17%)
		IGc2	243..309	CDD:197706	14/75 (19%)
		IG_like	330..424	CDD:214653
		IGc2	339..412	CDD:197706
		Ig	447..518	CDD:143165
		fn3	534..611	CDD:278470
		FN3	640..735	CDD:238020
dpr20	NP_612066.1	IG_like	278..365	CDD:214653	20/83 (24%)
		Ig	279..378	CDD:299845	24/98 (24%)
		Ig	400..471	CDD:299845	13/69 (19%)
		IG_like	402..480	CDD:214653	13/67 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810