DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Fas2 and DIP-iota

DIOPT Version :9

Sequence 1:	NP_001284854.1	Gene:	Fas2 / 31364	FlyBaseID:	FBgn0000635	Length:	885	Species:	Drosophila melanogaster
Sequence 2:	NP_001097100.1	Gene:	DIP-iota / 33925	FlyBaseID:	FBgn0031837	Length:	376	Species:	Drosophila melanogaster

Alignment Length:	296	Identity:	76/296 - (25%)
Similarity:	126/296 - (42%)	Gaps:	54/296 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   146 NQYPTLGQDYVVMCEVKADPNPTIDWLRNGDPIRTTNDKYVVQTN-------------GLLIRNV 197
            |....:|:|.::.|.|....:..:.|||.......:...:|:..|             .|.||:|
  Fly    39 NSTVPVGRDALLTCVVHDLVSFKVAWLRVDTQTILSIQNHVITKNHRISISHTEHRIWQLKIRDV 103

  Fly   198 QESDEGIYTCRAAVIETGELLERTIRVEVFIQPEIISLPTNLEAVE--GKPFAANCTARGKPVPE 260
            ||||.|.|.|:   |.|..:..:...::|.:.|:|:...|:.:.|.  |:.....|:|.|.|:|.
  Fly   104 QESDRGWYMCQ---INTDPMKSQMGYLDVVVPPDIVDYQTSQDVVRSTGQNVTLTCSATGVPMPT 165

  Fly   261 ISWIR-DATQLNVA-TADR--FQVNPQTGLVTISSVSQDDYGTYTCLAKNRAGV---VDQKTKLN 318
            |:|.| :||.:.:: ..||  |.|..|.  :|:..|.:...|.|.|:|.|  ||   |.::..|.
  Fly   166 ITWRREEATPILISDDGDREVFSVEGQN--LTLWQVQRSHMGAYLCIASN--GVPPTVSKRVMLV 226

  Fly   319 VLVRPQIYELYNV--TGARTKEIAITCRAKGRPAPAITFRRWGTQEE------YTNGQQDDDPRI 375
            |...|.|:..|:.  .|...| :.:.|..:.:|| ::.|  |....:      |.:...|...||
  Fly   227 VNFAPTIWTRYDTIYVGLGQK-LTLECITESQPA-SVNF--WLRDSQLLQGGSYESVSVDHVFRI 287

  Fly   376 ILEPNFDEERGESTGTLRISNAERSDDGLYQCIARN 411
            ::.             :.:....:.|.|.|.|.|:|
  Fly   288 VMR-------------ITLRPITKRDFGEYICRAKN 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fas2	NP_001284854.1	IG_like	39..133	CDD:214653
		IG_like	144..226	CDD:214653	23/92 (25%)
		IGc2	152..209	CDD:197706	20/69 (29%)
		I-set	230..319	CDD:254352	31/97 (32%)
		IGc2	243..309	CDD:197706	23/71 (32%)
		IG_like	330..424	CDD:214653	17/90 (19%)
		IGc2	339..412	CDD:197706	15/79 (19%)
		Ig	447..518	CDD:143165
		fn3	534..611	CDD:278470
		FN3	640..735	CDD:238020
DIP-iota	NP_001097100.1	IG_like	39..125	CDD:214653	23/88 (26%)
		Ig	39..122	CDD:299845	23/85 (27%)
		Ig	132..213	CDD:299845	26/82 (32%)
		IG_like	141..227	CDD:214653	28/89 (31%)
		IG_like	239..322	CDD:214653	17/89 (19%)
		IGc2	245..313	CDD:197706	16/83 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900