DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fas2 and DIP-eta

DIOPT Version :9

Sequence 1:	NP_001284854.1	Gene:	Fas2 / 31364	FlyBaseID:	FBgn0000635	Length:	885	Species:	Drosophila melanogaster
Sequence 2:	NP_001188701.2	Gene:	DIP-eta / 33793	FlyBaseID:	FBgn0031725	Length:	450	Species:	Drosophila melanogaster

Alignment Length:	414	Identity:	103/414 - (24%)
Similarity:	167/414 - (40%)	Gaps:	84/414 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 ESLALMITSLSVEMGGKYYCTASYANTEILEKGVTIKTYVAITWTNAPENQYPTLGQDYVVMCEV 161
            ::.||.:..|.:.|..:.|........|::   |..|....|....||      :|:|..:.|.|
  Fly    11 QTCALSVILLLILMSQQCYPQRVEVPAEVI---VDPKFSSPIVNMTAP------VGRDAFLTCVV 66

  Fly   162 KADPNP-TIDWLRNGDPIRTTNDKYVVQTN-------------GLLIRNVQESDEGIYTCRAAVI 212
            : |..| .:.|||.......|...:|:..|             .:.|::::|||:|.|.|:   |
  Fly    67 Q-DLGPYKVAWLRVDTQTILTIQNHVITKNQRIGIANSEHKTWTMRIKDIKESDKGWYMCQ---I 127

  Fly   213 ETGELLERTIRVEVFIQPEIISLPTNLEAV--EGKPFAANCTARGKPVPEISWIRDA-TQLNVAT 274
            .|..:..:...::|.:.|:|:..||:.:.|  ||......|.|.|.|.|.|:|.|:: ..:.:||
  Fly   128 NTDPMKSQMGYLDVVVPPDILDYPTSTDMVVREGSNVTLKCAATGSPEPTITWRRESGVPIELAT 192

  Fly   275 ADRFQVNPQTGLVTISSVSQDDYGTYTCLAKNRAGV---VDQKTKLNVLVRPQIYELYNVTGA-R 335
            .:.......|.|| |.:|.:...|.|.|:|.|  ||   |.::..|.|...|.|.....:.|| .
  Fly   193 GEEVMSIEGTDLV-IPNVRRHHMGAYLCIASN--GVPPSVSKRITLVVHFPPMITVQNQLIGAVE 254

  Fly   336 TKEIAITCRAKGRPAPAITFRRWGTQEEYTNGQQDDDPRIILEP------NFDEERG-ESTGTLR 393
            .|.:.:.|.::..|.   :...| |:|   .|:       |:.|      |..|..| .::..|.
  Fly   255 GKGVTLDCESEAYPK---SINYW-TRE---RGE-------IVPPGGKYSANVTEIGGYRNSMRLH 305

  Fly   394 ISNAERSDDGLYQCIARNKGADA------YKTGHITVEFAPDF--------------SHMKELPP 438
            |:...:::.|.|:|:|:|...|.      |:.....|.:..:|              ||......
  Fly   306 INPLTQAEFGSYRCVAKNSLGDTDGTIKLYRIPPNAVNYVENFEARHKGKKRTKSSESHHPARAQ 370

  Fly   439 VFSWE------QRKANLSCLAMGI 456
            ..|.|      :|||:||..|..|
  Fly   371 EHSGEDMENPGKRKADLSLGAESI 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fas2	NP_001284854.1	IG_like	39..133	CDD:214653	7/35 (20%)
		IG_like	144..226	CDD:214653	22/95 (23%)
		IGc2	152..209	CDD:197706	19/70 (27%)
		I-set	230..319	CDD:254352	31/94 (33%)
		IGc2	243..309	CDD:197706	22/66 (33%)
		IG_like	330..424	CDD:214653	23/107 (21%)
		IGc2	339..412	CDD:197706	17/79 (22%)
		Ig	447..518	CDD:143165	5/10 (50%)
		fn3	534..611	CDD:278470
		FN3	640..735	CDD:238020
DIP-eta	NP_001188701.2	Ig	51..141	CDD:299845	23/99 (23%)
		IG_like	51..137	CDD:214653	23/95 (24%)
		IG_like	153..237	CDD:214653	27/86 (31%)
		Ig	161..224	CDD:299845	21/65 (32%)
		IG_like	252..335	CDD:214653	21/96 (22%)
		Ig	258..333	CDD:143165	19/88 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810