DRSC/TRiP Functional Genomics Resources

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Protein Alignment Fas2 and Il1rapl1

DIOPT Version :9

Sequence 1:NP_001284854.1 Gene:Fas2 / 31364 FlyBaseID:FBgn0000635 Length:885 Species:Drosophila melanogaster
Sequence 2:NP_808796.1 Gene:Il1rapl1 / 317553 RGDID:727891 Length:696 Species:Rattus norvegicus


Alignment Length:556 Identity:111/556 - (19%)
Similarity:173/556 - (31%) Gaps:190/556 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   167 PTIDWLRNGDPIRTTNDKYVVQTNGLLIRNVQESDEGIYTCRAAVIETGELLERTIRVEVFIQPE 231
            |.|.|.:. ...:|.....|.:.:.|||:.|:|.|.|.|||....  .|.::.||..:.| ..|.
  Rat   177 PEILWYKE-CRTKTWRPSIVFKRDTLLIKEVKEDDIGNYTCELKY--GGFVVRRTTELTV-TAPL 237

  Fly   232 IISLPTNLEAVEGK--------PFAANCTAR------GKPVPEISW------IRDATQLNVATAD 276
            ....|..|..:|.|        ..:||.|.|      |...|.|.|      |.|..:..|..:|
  Rat   238 TDKPPKLLYPMESKLTIQETQLGGSANLTCRAFFGYSGDVSPLIYWMKGEKFIEDLDENRVWESD 302

  Fly   277 RFQVNPQTG------LVTISSVSQDDYGTYTCLAKN-----RAGVVDQKTKLNVLVR-------- 322
            ...:....|      .:.:.||.:.|.|.|:|..:|     .|.|:..|.:|...|.        
  Rat   303 IRILKEHLGEQEVSISLIVDSVEEGDLGNYSCYVENGNGRRHASVLLHKRELMYTVELAGGLGAI 367

  Fly   323 -------PQIYELYNVTGARTKEIAITCRAKGRPAPAITFRRWGTQE------------EYT--- 365
                   ..||:.|.:      ||.:..|           ..:|.:|            .||   
  Rat   368 LLLLVCSVTIYKCYKI------EIMLFYR-----------NHFGAEELDGDNKDYDAYLSYTKVD 415

  Fly   366 ----NGQQDDDPRIILE--PNFDEER-GESTGTLRISNAERSDDGLY-----QCIARNKGADAYK 418
                |.:..::.|..||  |:..|:. |..   |.|.:.:....|.|     :|:.::|      
  Rat   416 PDQWNQETGEEERFALEILPDMLEKHYGYK---LFIPDRDLIPTGTYIEDVARCVDQSK------ 471

  Fly   419 TGHITVEFAPDFSHMKELPPVFSWEQRKAN-----------LSCLAM-GIPN------------- 458
              .:.:...|::. ::....:|..|.|..|           :.|..: ||.|             
  Rat   472 --RLIIVMTPNYV-VRRGWSIFELETRLRNMLVTGEIKVILIECSELRGIMNYQEVEALKHTIKL 533

  Fly   459 -ATIEWHWNGRKIKDLYDTNLKIVGTGPRSDLIVHPVTR--QYYSGYKCIATNIHGTA---EHDM 517
             ..|:||                   ||:.:.:.....:  ||...:|.|....|..|   ....
  Rat   534 LTVIKWH-------------------GPKCNKLNSKFWKRLQYEMPFKRIEPITHEQALDVSEQG 579

  Fly   518 QLKEARVPDFVSEAKPSQLTATTMTFDIRGPSTELGLPILAYSVQYKEALNPDWSTAYNRSWSPD 582
            ...|.:....:|.|..:.....|...|:|.....      .|..|.::       ..|.||:..|
  Rat   580 PFGELQTVSAISMAAATSTALATAHPDLRSTFHN------TYHSQMRQ-------KHYYRSYEYD 631

  Fly   583 SP---------------------YIVEGLRPQTEYS 597
            .|                     .::.|.||||:.|
  Rat   632 VPPTGTLPLTSIGNQHTYCNIPMTLINGQRPQTKSS 667

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Fas2NP_001284854.1 IG_like 39..133 CDD:214653
IG_like 144..226 CDD:214653 18/58 (31%)
IGc2 152..209 CDD:197706 15/41 (37%)
I-set 230..319 CDD:254352 29/119 (24%)
IGc2 243..309 CDD:197706 22/96 (23%)
IG_like 330..424 CDD:214653 20/120 (17%)
IGc2 339..412 CDD:197706 18/99 (18%)
Ig 447..518 CDD:143165 16/101 (16%)
fn3 534..611 CDD:278470 16/85 (19%)
FN3 640..735 CDD:238020
Il1rapl1NP_808796.1 PHA02785 9..334 CDD:165149 42/160 (26%)
Ig1_IL1RAPL-1_like 32..135 CDD:143304
Ig 148..234 CDD:299845 19/60 (32%)
IGc2 260..341 CDD:197706 20/80 (25%)
TIR 405..559 CDD:279864 31/184 (17%)
Interaction with NCS1. /evidence=ECO:0000250 549..644 19/107 (18%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 659..680 6/9 (67%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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