DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Fas2 and Dscam4

DIOPT Version :9

Sequence 1:NP_001284854.1 Gene:Fas2 / 31364 FlyBaseID:FBgn0000635 Length:885 Species:Drosophila melanogaster
Sequence 2:NP_001261571.1 Gene:Dscam4 / 2769008 FlyBaseID:FBgn0263219 Length:1935 Species:Drosophila melanogaster


Alignment Length:887 Identity:188/887 - (21%)
Similarity:312/887 - (35%) Gaps:227/887 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 GELPPNSVGVFLALLLCSCSLIELTRAQSPILEIYPKQEVQRKPVG--KPLI------------- 51
            |||..|:.|...|....:|..:.....:..| ..||.:.:..:|.|  :|.|             
  Fly   187 GELYINNAGPNDAYKSYTCRTVNRLTGEVQI-STYPGRIIVTEPKGMVQPRINVEKHSMRHVVLN 250

  Fly    52 -LTCRPTVPEPSLVADLQWKDNRNNTILPKPNGRNQPPMYTETLPGESLALM-ITSLSVEMGGKY 114
             .|..|.:.:...|...:|....|..:||.        ..:|.:...|..|: ||...:|..|||
  Fly   251 GQTTLPCIAQGHPVPTYRWFKEENEQLLPL--------QLSERITIVSAGLLKITKARLEDSGKY 307

  Fly   115 YC-TASYANTEILEKGVTIKTYVAITWTNAPENQYPTLGQDYVVMCEVKADPNPTIDWLRNGDPI 178
            .| ..:.|..|.::..:|:.  ..:|....|:.|...:.:|....|.|...|...::||.:|.||
  Fly   308 LCWVNNTAGEETIQVSLTVT--APLTAHLQPQVQTVDVDKDAQFQCIVSGHPVHDVNWLHDGKPI 370

  Fly   179 -RTTNDKYVVQTNGLLIRNVQESDEGIYTCRAAVIETGELLERTIRVEV-FIQPEIISLPTNLEA 241
             |....:.:.....|:|:.||:.|.|:|.|  .|....|.::.|..::: ...||::...:....
  Fly   371 LRDNRVEILTDPPRLIIKKVQKEDPGMYQC--FVSNEWEQIQSTAELQLGDASPELLYWFSEQTL 433

  Fly   242 VEGKPFAANCTARGKPVPEISWIRDATQLNVATADRFQVNPQTGL-------VTISSVSQDDYGT 299
            ..|...:..|.|.|.|:|:.:|..|.  ..:..:.||.|.....:       |.||:|.::|.|.
  Fly   434 QPGPTVSLKCVATGNPLPQFTWSLDG--FPIPDSSRFLVGQYVTIHDDVISHVNISNVKEEDGGE 496

  Fly   300 YTCLAKNRAGVVDQKTKLNVLVRPQIYELYNVTGARTKEIAITCRAKGRPAPAITFRRWGTQEEY 364
            |||.|:|..|.|....|:|:...|.|.|:..:||....::.:.|...|.|...|.:.|       
  Fly   497 YTCTAQNAIGKVSHSAKVNIYGLPYIREMPKITGISGSDLIVKCPVAGYPIDKIHWER------- 554

  Fly   365 TNGQQDDDPRIILEPNFDEERGESTGTLRISNAERSDD-GLYQCIARNKGADAYKTG-HITVEFA 427
             :||        ..|....:|..:.|||.|...:|.:| |.|.|:|:||.....:.. .|.|...
  Fly   555 -DGQ--------TLPINRRQRAYNNGTLIIEQLQRLEDAGTYTCMAQNKQKQTSRRNVEIQVLVP 610

  Fly   428 PDFSHMKELPPVFSWEQRKANLSC--LAMGIPNATIEWHWNGRKIKDLYDTNLKIVGTGPR---- 486
            |....::.:..:.. |..:|.:||  |...:| .:..|..||:          .::|||..    
  Fly   611 PKIMPIQAMTNMLR-EGMRAAISCQILEGDLP-VSFRWERNGK----------PLIGTGNEVFRR 663

  Fly   487 -----SDLIVHPVTRQYYSGYKCIATNIHGTAEHDMQLKEARVPDFVSEAKPSQLTATTMTFDIR 546
                 :.|::..::..:...|.|||:|:.||....:.|.....|.::.|.|.|            
  Fly   664 LDEYSASLVIEHISSDHSGNYTCIASNVAGTERFTVPLTVNVPPKWILEPKDS------------ 716

  Fly   547 GPSTELGLPILAY---------SVQYKEALNP------DWSTAYNRSWSPDSPYIVEGLRPQTEY 596
              |.:.|..:|.:         ::.:|:|:.|      |:.........|:.....:.:..:::.
  Fly   717 --SAQAGADVLLHCQSSGYPTPTITWKKAIGPTPGEYKDFLYEPTVQLFPNGTIFFKKISKESQG 779

  Fly   597 SFRFAARNQVGLG--------------------------------------------NWGVNQQQ 617
            .|...|:|.:|.|                                            .|.:...|
  Fly   780 HFLCEAKNNIGSGVSKVIFLKVNVPAHFQTKTKQISVAKGKQVHVQCNVQGDNPIDFKWKIQATQ 844

  Fly   618 S-----------------------------TPR-------------------------RSAPEEP 628
            .                             |.|                         :..||:|
  Fly   845 QYLDESLDSRYTIRDQVLDDGMVSELGISHTYRQDTGIYICQASNAFGQDEMSIQLIVQEVPEQP 909

  Fly   629 KPLHNPVQHDKEEPVVVSPYSDHFELRWGVPADNGEPIDRYQIKYCPGVKISGTWTELENSCNTV 693
            |.|.           :.|..|...:|.|..|.....||:.|.|.|   .:||..|...|:.  |:
  Fly   910 KNLR-----------INSQQSRSLQLTWSQPFAGNSPIEEYHIYY---KQISDIWQNAEHL--TI 958

  Fly   694 EVMETTSFEMTQLVGNTYYRIELKAHNAIGYSSPASIIMKTT 735
            ...:|. ..:.||.....|.|.:.|.|.:|.|..:.::..||
  Fly   959 AGAQTV-INIQQLRPAKAYHIRMSAENKLGASEFSEVVQVTT 999

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Fas2NP_001284854.1 IG_like 39..133 CDD:214653 24/111 (22%)
IG_like 144..226 CDD:214653 23/82 (28%)
IGc2 152..209 CDD:197706 18/57 (32%)
I-set 230..319 CDD:254352 27/95 (28%)
IGc2 243..309 CDD:197706 22/72 (31%)
IG_like 330..424 CDD:214653 24/95 (25%)
IGc2 339..412 CDD:197706 19/73 (26%)
Ig 447..518 CDD:143165 19/81 (23%)
fn3 534..611 CDD:278470 14/135 (10%)
FN3 640..735 CDD:238020 24/94 (26%)
Dscam4NP_001261571.1 Ig 31..124 CDD:416386
Ig strand A 32..35 CDD:409353
Ig strand A' 41..45 CDD:409353
Ig strand B 48..57 CDD:409353
Ig strand D 75..78 CDD:409353
Ig strand E 83..88 CDD:409353
Ig strand F 101..109 CDD:409353
Ig strand G 112..124 CDD:409353
Ig 235..326 CDD:416386 21/98 (21%)
Ig strand A 235..238 CDD:409353 1/2 (50%)
Ig strand A' 244..248 CDD:409353 0/3 (0%)
Ig strand B 251..258 CDD:409353 2/6 (33%)
Ig strand C 266..271 CDD:409353 1/4 (25%)
Ig strand C' 276..279 CDD:409353 0/2 (0%)
Ig strand D 285..289 CDD:409353 0/3 (0%)
Ig strand E 292..298 CDD:409353 2/5 (40%)
Ig strand F 305..313 CDD:409353 4/7 (57%)
Ig strand G 316..326 CDD:409353 1/9 (11%)
IgC2_3_Dscam 329..417 CDD:409549 24/89 (27%)
Ig strand B 347..351 CDD:409549 0/3 (0%)
Ig strand C 360..364 CDD:409549 0/3 (0%)
Ig strand E 383..387 CDD:409549 1/3 (33%)
Ig strand F 397..402 CDD:409549 2/6 (33%)
Ig strand G 410..413 CDD:409549 0/2 (0%)
IgI_4_Dscam 422..516 CDD:409548 27/95 (28%)
Ig strand B 439..443 CDD:409548 0/3 (0%)
Ig strand C 452..456 CDD:409548 0/3 (0%)
Ig strand E 482..486 CDD:409548 1/3 (33%)
Ig strand F 496..501 CDD:409548 3/4 (75%)
Ig strand G 509..512 CDD:409548 0/2 (0%)
IgI_5_Dscam 520..607 CDD:409550 27/102 (26%)
Ig strand B 536..540 CDD:409550 0/3 (0%)
Ig strand C 549..553 CDD:409550 1/3 (33%)
Ig strand E 571..575 CDD:409550 3/3 (100%)
Ig strand F 586..591 CDD:409550 2/4 (50%)
Ig strand G 600..603 CDD:409550 0/2 (0%)
Ig 610..703 CDD:416386 22/104 (21%)
Ig strand A 611..613 CDD:409353 1/1 (100%)
Ig strand A' 620..624 CDD:409353 0/3 (0%)
Ig strand B 627..636 CDD:409353 3/8 (38%)
Ig strand C 641..648 CDD:409353 2/7 (29%)
Ig strand C' 650..652 CDD:409353 1/11 (9%)
Ig strand D 659..664 CDD:409353 0/4 (0%)
Ig strand E 668..675 CDD:409353 1/6 (17%)
Ig strand F 682..690 CDD:409353 4/7 (57%)
Ig strand G 693..702 CDD:409353 2/8 (25%)
IgI_7_Dscam 706..801 CDD:409546 17/108 (16%)
Ig strand B 724..728 CDD:409546 1/3 (33%)
Ig strand C 737..741 CDD:409546 0/3 (0%)
Ig strand E 766..770 CDD:409546 0/3 (0%)
Ig strand F 780..785 CDD:409546 1/4 (25%)
Ig strand G 794..797 CDD:409546 0/2 (0%)
Ig 818..904 CDD:416386 4/85 (5%)
putative Ig strand B 820..827 CDD:409353 0/6 (0%)
putative Ig strand C 835..841 CDD:409353 1/5 (20%)
putative Ig strand C' 853..856 CDD:409353 0/2 (0%)
putative Ig strand D 862..866 CDD:409353 0/3 (0%)
putative Ig strand E 868..874 CDD:409353 0/5 (0%)
putative Ig strand F 881..889 CDD:409353 0/7 (0%)
putative Ig strand G 892..902 CDD:409353 0/9 (0%)
FN3 906..999 CDD:238020 29/109 (27%)
FN3 1006..1110 CDD:238020
fn3 1117..1203 CDD:394996
FN3 1215..1307 CDD:238020
Ig <1334..1401 CDD:416386
Ig strand C 1345..1349 CDD:409353
Ig strand D 1363..1366 CDD:409353
Ig strand E 1367..1372 CDD:409353
Ig strand F 1380..1388 CDD:409353
Ig strand G 1394..1401 CDD:409353
FN3 1405..1494 CDD:238020
FN3 1499..1580 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR10075
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
32.910

Return to query results.
Submit another query.