DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fas2 and dpr9

DIOPT Version :9

Sequence 1:	NP_001284854.1	Gene:	Fas2 / 31364	FlyBaseID:	FBgn0000635	Length:	885	Species:	Drosophila melanogaster
Sequence 2:	NP_001287332.1	Gene:	dpr9 / 2768670	FlyBaseID:	FBgn0038282	Length:	602	Species:	Drosophila melanogaster

Alignment Length:	229	Identity:	62/229 - (27%)
Similarity:	89/229 - (38%)	Gaps:	57/229 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   238 NLEAVEGKPFAANCTARG----KPVPEISWI--RDATQLNVA----TAD-RFQV--NPQT--GLV 287
            |:.|:.||....||..:.    ..:.::||:  ||...|.|.    |:| ||:.  .|||  .::
  Fly   265 NVTALLGKTAYLNCRVKNLGNKTMLLQVSWVRHRDIHLLTVGRYTYTSDQRFRAIHQPQTEDWML 329

  Fly   288 TISSVSQDDYGTYTCLAKN--------RAGVVDQKTKLNVLVRPQIYELYNVTGARTKEIAITCR 344
            .|......|.|.|.|....        ...||:..|:  ::..|   :||..:|:   .|.:||.
  Fly   330 QIKYPQHRDSGIYECQVSTTPHMSHYIHLNVVEPSTE--IIGAP---DLYIESGS---TINLTCI 386

  Fly   345 AKGRP-APAITFRRWGTQEEYTNGQQDDDPRIILEPNFDEERG----------ESTGTLRISNAE 398
            .:..| .||..|  |.....:.:     .|:||   |:|..||          .:|..|.|.:|.
  Fly   387 IQNSPEPPAYIF--WNHNNAFPS-----HPQII---NYDSPRGGVSVVTNKGDTTTSFLLIKSAR 441

  Fly   399 RSDDGLYQCIARNKGADAYKTGHITVEFAPDFSH 432
            .||.|.|||...|.     |...:||......||
  Fly   442 PSDSGHYQCNPSNA-----KPKSVTVHVLNGVSH 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fas2	NP_001284854.1	IG_like	39..133	CDD:214653
		IG_like	144..226	CDD:214653
		IGc2	152..209	CDD:197706
		I-set	230..319	CDD:254352	27/103 (26%)
		IGc2	243..309	CDD:197706	22/88 (25%)
		IG_like	330..424	CDD:214653	28/104 (27%)
		IGc2	339..412	CDD:197706	25/83 (30%)
		Ig	447..518	CDD:143165
		fn3	534..611	CDD:278470
		FN3	640..735	CDD:238020
dpr9	NP_001287332.1	Ig	263..361	CDD:299845	24/95 (25%)
		IG_like	263..360	CDD:214653	24/94 (26%)
		IG_like	371..464	CDD:214653	33/113 (29%)
		IGc2	377..456	CDD:197706	27/96 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900