DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fas2 and Lsamp

DIOPT Version :9

Sequence 1:	NP_001284854.1	Gene:	Fas2 / 31364	FlyBaseID:	FBgn0000635	Length:	885	Species:	Drosophila melanogaster
Sequence 2:	XP_030104997.1	Gene:	Lsamp / 268890	MGIID:	1261760	Length:	392	Species:	Mus musculus

Alignment Length:	328	Identity:	84/328 - (25%)
Similarity:	134/328 - (40%)	Gaps:	41/328 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   238 NLEAVEGKPFAANCTARGKPVPEISWIRDATQLNVATADRFQVNPQTGL---------VTISSVS 293
            |:...:|......|....|. .:::|: :.:.:..|..|::.::|:..|         :.|..|.
Mouse    71 NITVRQGDTAILRCVVEDKN-SKVAWL-NRSGIIFAGHDKWSLDPRVELEKRHALEYSLRIQKVD 133

  Fly   294 QDDYGTYTCLAKNRAGVVDQKTKLNVLVRPQIYEL-YNVTGARTKEIAITCRAKGRPAPAITFRR 357
            ..|.|:|||..:.:......:..|.|.|.|:|..: .:||......:.:.|.|.|||.|.||:|.
Mouse   134 VYDEGSYTCSVQTQHEPKTSQVYLIVQVPPKISNISSDVTVNEGSNVTLVCMANGRPEPVITWRH 198

  Fly   358 WGTQEEYTNGQQDDDPRIILEPNFDEERGESTGTLRISNAERSDDGLYQCIARNKGADA-YKTGH 421
                               |.|...|..||.. .|.|....|...|.|:|.|.|:.:.| .|...
Mouse   199 -------------------LTPLGREFEGEEE-YLEILGITREQSGKYECKAANEVSSADVKQVK 243

  Fly   422 ITVEFAPDFSHMKELPPVFSWEQRKANLSCLAMGIPNATIEWHWNGRKIKDLYDTNLKIVGTGPR 486
            :||.:.|..:..|.......   |:|:|.|.|..:|....||:.:..:|...  ..|:|..|..:
Mouse   244 VTVNYPPTITESKSNEATTG---RQASLKCEASAVPAPDFEWYRDDTRINSA--NGLEIKSTEGQ 303

  Fly   487 SDLIVHPVTRQYYSGYKCIATNIHGTAEHDMQLKEARVPDFVSEAKPSQLTATTMTFDIRGPSTE 551
            |.|.|..||.::|..|.|:|.|..|.....:.|.:..:|   :...|.|...||:.|..:||.:.
Mouse   304 SSLTVTNVTEEHYGNYTCVAANKLGVTNASLVLFKRVLP---TVPHPIQEIGTTVHFKPKGPGSV 365

  Fly   552 LGL 554
            .|:
Mouse   366 RGI 368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fas2	NP_001284854.1	IG_like	39..133	CDD:214653
		IG_like	144..226	CDD:214653
		IGc2	152..209	CDD:197706
		I-set	230..319	CDD:254352	17/89 (19%)
		IGc2	243..309	CDD:197706	15/74 (20%)
		IG_like	330..424	CDD:214653	26/94 (28%)
		IGc2	339..412	CDD:197706	21/72 (29%)
		Ig	447..518	CDD:143165	22/70 (31%)
		fn3	534..611	CDD:278470	7/21 (33%)
		FN3	640..735	CDD:238020
Lsamp	XP_030104997.1	Ig	69..159	CDD:386229	17/89 (19%)
		Ig_3	163..232	CDD:372822	25/88 (28%)
		Ig_3	250..325	CDD:372822	23/79 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910