DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fas2 and zig-2

DIOPT Version :9

Sequence 1:	NP_001284854.1	Gene:	Fas2 / 31364	FlyBaseID:	FBgn0000635	Length:	885	Species:	Drosophila melanogaster
Sequence 2:	NP_510069.1	Gene:	zig-2 / 192087	WormBaseID:	WBGene00006979	Length:	238	Species:	Caenorhabditis elegans

Alignment Length:	202	Identity:	51/202 - (25%)
Similarity:	77/202 - (38%)	Gaps:	40/202 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   138 ITWTNAPENQYPTLGQDYVVMCEVKADPNPTIDWLRNGDPIR---TTNDKYVVQTNGLLIRN--- 196
            :.:|..|.:...|.|:.:|:.|.....|.|:|.|..||..|:   |:|....:..:|..:.|
Worm    33 LKFTRTPNDSNVTFGEKFVLSCGANGAPLPSIYWELNGMRIQGEETSNVYENILNDGKQVSNAAM 97

  Fly   197 ---------VQESDEGIYTCRAAVIETG-ELLERTIRVEVFIQPEIISLPTNLEAVEGKPF---- 247
                     ....:.|.|.|   :|:.| ..||...:|.|.......:|..|     |.||
Worm    98 VSSHYRIPCATARNSGAYKC---IIDNGLTKLEHVAKVFVGGNKTNCALNDN-----GAPFISMT 154

  Fly   248 ----------AANCTARGKPVPEISWIRDATQLNVATADRFQVNPQTGLVTISSVSQDDYGTYTC 302
                      |...:.|.:...|.|| ....||.....:|:|:.|...|: |.::|..|.|.|.|
Worm   155 VDFRLEISNNAVALSCRSETATEWSW-HKGEQLLTNDGERYQMFPSGDLI-IRNISWSDMGEYNC 217

  Fly   303 LAKNRAG 309
            .|:|..|
Worm   218 TARNHFG 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fas2	NP_001284854.1	IG_like	39..133	CDD:214653
		IG_like	144..226	CDD:214653	24/97 (25%)
		IGc2	152..209	CDD:197706	17/71 (24%)
		I-set	230..319	CDD:254352	25/94 (27%)
		IGc2	243..309	CDD:197706	22/79 (28%)
		IG_like	330..424	CDD:214653
		IGc2	339..412	CDD:197706
		Ig	447..518	CDD:143165
		fn3	534..611	CDD:278470
		FN3	640..735	CDD:238020
zig-2	NP_510069.1	I-set	34..134	CDD:254352	25/102 (25%)
		Ig	34..121	CDD:299845	21/89 (24%)
		Ig	<179..232	CDD:299845	17/48 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900