DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fas2 and Il1r2

DIOPT Version :9

Sequence 1:	NP_001284854.1	Gene:	Fas2 / 31364	FlyBaseID:	FBgn0000635	Length:	885	Species:	Drosophila melanogaster
Sequence 2:	NP_001347729.1	Gene:	Il1r2 / 16178	MGIID:	96546	Length:	428	Species:	Mus musculus

Alignment Length:	383	Identity:	79/383 - (20%)
Similarity:	135/383 - (35%)	Gaps:	126/383 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 SCSLIELTR--------------------------AQSPILEIYP--------------KQEVQR 43
            ||:|.:|.|                          ::|||....|              |.|::.
Mouse     9 SCALRKLVRTMFILLVLVTGVSAFTTPTVVHTGKVSESPITSEKPTVHGDNCQFRGREFKSELRL 73

  Fly    44 KPVGKPLILTCRPTVPEPSLVAD----LQWKDNRNNTILPKPNGRNQPPMYTETLPGESLALMIT 104
            :  |:|::|.| |..|...:.:.    |.|....::.::|    |::|.|:.     :...|.|.
Mouse    74 E--GEPVVLRC-PLAPHSDISSSSHSFLTWSKLDSSQLIP----RDEPRMWV-----KGNILWIL 126

  Fly   105 SLSVEMGGKYYCTASYANTEILEK-GVTIKTYVAITWTNAPENQY---PTLGQDYVVMCE----- 160
            ....:..|.|.||  :.|....|: .|.:|.: ..|..:.|...|   ..|....:::|.
Mouse   127 PAVQQDSGTYICT--FRNASHCEQMSVELKVF-KNTEASLPHVSYLQISALSTTGLLVCPDLKEF 188

  Fly   161 VKADPNPTIDW--------------LRNGDPIRTTNDKYVVQTNGLLIRNVQESDEGIYTCRAAV 211
            :.::.:..|.|              |..|||.|            |||.|....|.|.|.|....
Mouse   189 ISSNADGKIQWYKGAILLDKGNKEFLSAGDPTR------------LLISNTSMDDAGYYRCVMTF 241

  Fly   212 IETGELLERTIRVEVFIQ-------PEIIS----LPTNLEA---VEGKPFAANCTARGKPVPEIS 262
            ...|:....|..:|:.::       |.|||    :|.:|.:   |..|.|....|:....|   .
Mouse   242 TYNGQEYNITRNIELRVKGTTTEPIPVIISPLETIPASLGSRLIVPCKVFLGTGTSSNTIV---W 303

  Fly   263 WIRDATQLNVA---------TADRFQVNPQTGLVTIS----SVSQDDYGT-YTCLAKN 306
            |:.::|.::.|         ...::..|.: ..|.:|    .|:::|..| :.|:|.|
Mouse   304 WLANSTFISAAYPRGRVTEGLHHQYSENDE-NYVEVSLIFDPVTREDLHTDFKCVASN 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fas2	NP_001284854.1	IG_like	39..133	CDD:214653	22/98 (22%)
		IG_like	144..226	CDD:214653	21/103 (20%)
		IGc2	152..209	CDD:197706	16/75 (21%)
		I-set	230..319	CDD:254352	23/98 (23%)
		IGc2	243..309	CDD:197706	16/78 (21%)
		IG_like	330..424	CDD:214653
		IGc2	339..412	CDD:197706
		Ig	447..518	CDD:143165
		fn3	534..611	CDD:278470
		FN3	640..735	CDD:238020
Il1r2	NP_001347729.1	PHA02785	54..382	CDD:165149	70/338 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000