Protein Alignment Fas2 and Fas2

DIOPT Version :10

• Sequence 1: NP_001284854.1
• Gene: Fas2 / 31364
• FlyBaseID: FBgn0000635
• Length: 885
• Species: Drosophila melanogaster
• Sequence 2: XP_061503119.1
• Gene: Fas2 / 1273160
• VectorBaseID: AGAMI1_011233
• Length: 911
• Species: Anopheles gambiae
• Alignment Length: 899
• Identity: 512/899 - (56%)
• Similarity: 652/899 - (72%)
• Gaps: 32/899 - (3%)

  Fly    15 LLLCSCSLIELTRAQS-PILEIYPKQEVQRKPVGKPLILTCRPTVPEPSLVADLQWKDNRNNTIL 78
            :||...:||.:..:|: |.|:|.|...|||||||..|:|||||.||:.:|::||:|.||||.|||
Mosquito    17 MLLVWMTLIGMAHSQNQPRLKILPASSVQRKPVGHSLLLTCRPEVPDTNLISDLRWNDNRNMTIL 81

  Fly    79 PKP------------------NGRNQPPMYTETLP-GESLALMITSLSVEMGGKYYCTASYANTE 124
            |||                  .|::.|.:|||::. |.:|||:..||...|.|.|:|.|||:.||
Mosquito    82 PKPMNYYYPLYDSKGRKLPTKAGQSSPLIYTESIAGGTALALIFNSLQESMAGTYFCAASYSVTE 146

  Fly   125 ILEKGVTIKTYVAITWTNAPENQYPTLGQDYVVMCEVKADPNPTIDWLRNGDPIRTTNDKYVVQT 189
            .|...|.::|||||||.:||.:|.|.:|.||:|.|||.|:|..|:|||||||.|:::. :||::.
Mosquito   147 KLNAAVVVETYVAITWKDAPTDQRPLMGTDYIVRCEVTANPPATVDWLRNGDQIKSSG-RYVIEN 210

  Fly   190 NGLLIRNVQESDEGIYTCRAAVIETGELLERTIRVEVFIQPEIISLPTNLEAVEGKPFAANCTAR 254
            .||||:|:.|:|:|:|||||||:.||||..|.|||||.|.|::..||..::||||:.|:..|.|.
Mosquito   211 RGLLIKNITEADDGVYTCRAAVMSTGELKNREIRVEVQIMPQVQRLPLVMDAVEGQSFSVMCNAT 275

  Fly   255 GKPVPEISWIRDATQLNVATADRFQVNPQTGLVTISSVSQDDYGTYTCLAKNRAGVVDQKTKLNV 319
            ||||||..||:..||.|.|..|||.||..||.:.||:|.|.|:..|.|:|:|.||..:...||||
Mosquito   276 GKPVPEFQWIKKGTQQNAADLDRFSVNSITGQLDISTVEQQDHDNYACIARNPAGQSESVMKLNV 340

  Fly   320 LVRPQIYELYNVTGARTKEIAITCRAKGRPAPAITFRRWGTQEEYTNGQQDDDPRIILEPNFDEE 384
            |:||:|.|..|:|.:..:|....|:|.|||||.|||||:||.|||:.|.|..|.|||||.:.|:|
Mosquito   341 LIRPKIIEFINITVSENEEAVFVCKAFGRPAPEITFRRYGTVEEYSIGLQVSDDRIILEQSTDDE 405

  Fly   385 RGESTGTLRISNAERSDDGLYQCIARNKGADAYKTGHITVEFAPDFSHMKELPPVFSWEQRKANL 449
            :||:.||||||....:|||||:|||||:|..|:|.||||||:.|.|.|:|.||||::||:|.|||
Mosquito   406 KGETVGTLRISKLATTDDGLYECIARNRGDVAFKVGHITVEYRPIFDHLKALPPVYTWEERPANL 470

  Fly   450 SCLAMGIPNATIEWHWNGRKIKDLYDTNLKIVGTGPRSDLIVHPVTRQYYSGYKCIATNIHGTAE 514
            ||.|..||||||||.:|.|:|:||||.||:|...|.|||||:.|..|:||:.|||:|.|..|:||
Mosquito   471 SCFAQAIPNATIEWRFNDRRIQDLYDQNLRIENEGLRSDLIITPRDRRYYTAYKCVANNRLGSAE 535

  Fly   515 HDMQLKEARVPDFVSEAKPSQLTATTMTFDIRGPSTELGLPILAYSVQYKEALNPDWSTAYNRSW 579
            |.|:|:|||:|:.|.:|||..::||::||||..|..|.|||:.|:|||:||....||:.|.||:|
Mosquito   536 HIMELREARIPEMVPQAKPRIVSATSITFDIMAPPVEPGLPLTAFSVQWKEQFQSDWNFALNRTW 600

  Fly   580 SPDSPYIVEGLRPQTEYSFRFAARNQVGLGNWGVNQQQSTPRRSAPEEPKPLHNPVQHDKE--EP 642
            |||||||||||||||.|||||||||.|||..||....|||||||.||.|:.||.|:|.::|  :|
Mosquito   601 SPDSPYIVEGLRPQTAYSFRFAARNVVGLSQWGAYVDQSTPRRSEPETPRILHTPIQDEEEDSDP 665

  Fly   643 VVVSPYSDHFELRWGVPADNGEPIDRYQIKYCPGVKISGTWTELENSCNTVEVMETTSFEMTQLV 707
            :|.|||:|||::||.:|.|||||||.|:||||||.|::|.|||:|..|...::...|::||..|.
Mosquito   666 IVTSPYADHFDMRWSIPVDNGEPIDMYRIKYCPGTKVNGYWTEMEEHCIEQDIARMTNYEMRSLQ 730

  Fly   708 GNTYYRIELKAHNAIGYSSPASIIMKTTRGIDVIQVAERQVFSSAAIVGIAIGGVLLLLFVVDLL 772
            .:|||||||.||||||:|.||.::|||.|||||:...:....||||::||.||.|:|||.:.|||
Mosquito   731 ADTYYRIELMAHNAIGFSKPAHVLMKTARGIDVVLRVDSPTLSSAAVIGIVIGSVVLLLLIADLL 795

  Fly   773 CCITVHMGVMATMCRKAKRSPSEIDDEAKLGSLYGWRFPLPYCSGQLVKEPPPSPLPLPPP-VKL 836
            ||...::|::||:|||.|||||::|||||||||||||||||||||.|:||.|||||||||| |||
Mosquito   796 CCAFGNLGILATLCRKTKRSPSDLDDEAKLGSLYGWRFPLPYCSGSLIKERPPSPLPLPPPIVKL 860

  Fly   837 GGSPMSTPL-DEKEPLRTP----TGSIKQNSTIEFDGRFVHSRSGEIIGKNSAV 885
            |.   :||| |||:||.||    ...:|.||::|:|||.|||||||||||||||
Mosquito   861 GA---TTPLEDEKQPLNTPQQPAASPLKVNSSVEYDGRVVHSRSGEIIGKNSAV 911

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fas2	NP_001284854.1	Ig	33..121	CDD:472250	49/106 (46%)
		Ig strand B	50..54	CDD:409353	2/3 (67%)
		Ig strand C	66..70	CDD:409353	2/3 (67%)
		Ig strand E	99..103	CDD:409353	3/3 (100%)
		Ig strand F	113..118	CDD:409353	2/4 (50%)
		Ig	139..209	CDD:472250	37/69 (54%)
		Ig strand B	156..159	CDD:409353	1/2 (50%)
		Ig strand C	168..172	CDD:409353	2/3 (67%)
		Ig strand E	190..194	CDD:409353	2/3 (67%)
		Ig strand F	204..209	CDD:409353	3/4 (75%)
		IgI_4_MYLK-like	229..319	CDD:409568	42/89 (47%)
		Ig strand A	229..232	CDD:409568	1/2 (50%)
		Ig strand A'	238..241	CDD:409568	0/2 (0%)
		Ig strand B	246..254	CDD:409568	2/7 (29%)
		Ig strand C	260..264	CDD:409568	1/3 (33%)
		Ig strand C'	267..270	CDD:409568	1/2 (50%)
		Ig strand D	277..281	CDD:409568	2/3 (67%)
		Ig strand E	285..290	CDD:409568	1/4 (25%)
		Ig strand F	298..306	CDD:409568	3/7 (43%)
		Ig strand G	309..319	CDD:409568	3/9 (33%)
		IG_like	330..424	CDD:214653	54/93 (58%)
		Ig strand B	339..343	CDD:409353	0/3 (0%)
		Ig strand C	352..356	CDD:409353	2/3 (67%)
		Ig strand E	388..394	CDD:409353	3/5 (60%)
		Ig strand F	404..409	CDD:409353	3/4 (75%)
		Ig	447..515	CDD:409353	41/67 (61%)
		Ig strand B	447..451	CDD:409353	3/3 (100%)
		Ig strand C	460..464	CDD:409353	3/3 (100%)
		Ig strand E	487..491	CDD:409353	3/3 (100%)
		Ig strand F	501..506	CDD:409353	3/4 (75%)
		FN3	525..619	CDD:238020	58/93 (62%)
		FN3	640..735	CDD:238020	55/96 (57%)
Fas2	XP_061503119.1	None