DRSC/TRiP Functional Genomics Resources

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Protein Alignment Fas2 and Kirrel2

DIOPT Version :9

Sequence 1:NP_001284854.1 Gene:Fas2 / 31364 FlyBaseID:FBgn0000635 Length:885 Species:Drosophila melanogaster
Sequence 2:XP_038957463.1 Gene:Kirrel2 / 100359836 RGDID:1308456 Length:711 Species:Rattus norvegicus


Alignment Length:848 Identity:154/848 - (18%)
Similarity:274/848 - (32%) Gaps:323/848 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly   125 ILEKGVT-IKTYVAIT------WTNAPENQYPTLGQDYVVMCEVKADPNPTIDWLRNGDPIRTTN 182
            :|.||:. :.:.:.:.      :...||:....|||:..:.|.:.| ....:.|.::|..:....
  Rat    12 VLHKGIPFLSSAIPLLLGSSPHFLQQPEDMVVLLGQEARLPCALGA-YRGLVQWTKDGLALGGER 75

  Fly   183 D-----KYVVQTNG------LLIRNVQESDEGIYTCRAAVIETGELLERTIRVEVFIQPE---II 233
            |     :|.:..|.      |.|:.|:..||..|.|:|:  :.| |..|..::.|.:.||   ::
  Rat    76 DLPGWSRYWISGNSASGQHDLHIKPVELEDEASYECQAS--QAG-LRSRPAQLHVMVPPEAPQVL 137

  Fly   234 SLPTNLEAVEGKPFAANCTARG--KPVPEISWIRDATQLNVATADRFQVNPQ-TGLVT----ISS 291
            ..| ::..|.|.|....|.:||  :|.||:.|.||..:|:..:..:..:..: ||.|.    ::.
  Rat   138 GGP-SVSLVAGVPGNLTCRSRGDARPAPELLWFRDGIRLDGTSFHQITLRDKATGTVENTLFLTP 201

  Fly   292 VSQDDYGTYTCLAKNRAGVVDQKTKLNVLVR----------PQIYELYNVTGARTKEIAITCRAK 346
            .||||..|..|.|:::|....:.|.:.:.::          ||       |....:::...|:|.
  Rat   202 SSQDDGATLICRARSQALPTGRDTAVTLSLQYPPMVTLSAEPQ-------TAQEGEKVTFLCQAT 259

  Fly   347 GRPAPAITFRRWGTQEEYTNGQQDDDPRIILEPNFDEERGESTGTLRISNAERSD--DGLYQCIA 409
            .:  |.:|..||........|.:.....::.:..|..|......:..:.:|.||.  :.||..|.
  Rat   260 AQ--PPVTGYRWAKGGSPVLGARGPRLEVVADATFLTEPVSCEVSNAVGSANRSTALEVLYGPIL 322

  Fly   410 RNKGADAYKTGHITVEFAPDFSHMKELPPVFSWEQRKANLSCLAMGIPNATIEWHWNGRKIKDLY 474
            :.|...      ::|:...|                 |:.||:..|.|...|.|           
  Rat   323 QAKPKP------VSVDVGKD-----------------ASFSCVWRGNPLPRISW----------- 353

  Fly   475 DTNL---KIVGTGPRSDLIVHPVTRQYYSGYKCIA----TNI-HGTAEHDMQLKEARVPDFVSEA 531
             |.|   :::.:||  .|.:..|..:....|.|.|    |.: .|||:..:.:   ..|..|:..
  Rat   354 -TRLGGSQVLSSGP--TLRLPSVALEDAGDYVCRAEPRRTGVGGGTAQARLTV---NAPPVVTAL 412

  Fly   532 KPSQLTATTMTFDIRGPSTELGLPILAYSVQYKEALNPDWSTAYNRSWS---------PDSPYIV 587
            .|:...       :|||:.   |..:.::....:::...|...:..:.|         | :|.:.
  Rat   413 HPAPAF-------LRGPAR---LQCVVFASPAPDSVVWSWDEGFLEAGSLGRFLVEAFP-APEVE 466

  Fly   588 EGLRP------------QTEYS--FRFAARNQVGLGN---------------------------- 610
            .|..|            :::::  |..:|||::|.|.                            
  Rat   467 GGQGPGLISVLHISGTQESDFTTGFNCSARNRLGEGRVQIHLGRRDLLPTVRLVAGAASAATSLF 531

  Fly   611 ----------W---GVNQQQSTPRRSAPEEPKPLHNPVQH----DKEEPVVVSPYSDHFELRWGV 658
                      |   .:::|::..|.....|....|.|.:.    :...|:|   ::||.:|    
  Rat   532 MVITGVVLCCWRHGSLSKQKNLVRIPGSSEGSSAHGPEEETGSSEDRGPIV---HTDHNDL---- 589

  Fly   659 PADNGEPIDRYQIKYCPGVKISGTWTELENSCNTVEVMETTSFEMTQLVGNTYYRIELKAHNAIG 723
                                                |:|......|:...|.||::         
  Rat   590 ------------------------------------VLEENEALETKDPTNGYYKV--------- 609

  Fly   724 YSSPASIIMKTTRGIDVIQVAERQVFSSAAIVGIAIGGVLLLLFVVDLLCCITVHMGVMATMCRK 788
                        ||:.|           :..:|.|.||.|.|                       
  Rat   610 ------------RGVSV-----------SLSLGEAPGGGLFL----------------------- 628

  Fly   789 AKRSPSEIDDEAKLGSLYGWRFPLPYCSGQLVKEPPPSPLPLPPPVKLGGSP----MSTPLDEKE 849
                                              |||||:.||      |:|    ....||...
  Rat   629 ----------------------------------PPPSPMGLP------GTPTYYDFKPHLDLVP 653

  Fly   850 PLR 852
            |.|
  Rat   654 PCR 656

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Fas2NP_001284854.1 IG_like 39..133 CDD:214653 3/8 (38%)
IG_like 144..226 CDD:214653 23/92 (25%)
IGc2 152..209 CDD:197706 16/67 (24%)
I-set 230..319 CDD:254352 28/98 (29%)
IGc2 243..309 CDD:197706 22/72 (31%)
IG_like 330..424 CDD:214653 17/95 (18%)
IGc2 339..412 CDD:197706 15/74 (20%)
Ig 447..518 CDD:143165 20/78 (26%)
fn3 534..611 CDD:278470 16/137 (12%)
FN3 640..735 CDD:238020 11/94 (12%)
Kirrel2XP_038957463.1 IG_like 38..127 CDD:214653 23/92 (25%)
Ig strand A' 40..44 CDD:409353 0/3 (0%)
Ig strand B 48..57 CDD:409353 1/8 (13%)
Ig strand C 62..66 CDD:409353 1/3 (33%)
Ig strand D 75..85 CDD:409353 2/9 (22%)
Ig strand E 88..100 CDD:409353 3/11 (27%)
Ig strand F 107..115 CDD:409353 3/9 (33%)
Ig strand G 117..127 CDD:409353 3/10 (30%)
Ig 133..231 CDD:416386 26/98 (27%)
Ig strand A 134..137 CDD:409353 0/2 (0%)
Ig strand A' 140..144 CDD:409353 1/4 (25%)
Ig strand B 151..158 CDD:409353 1/6 (17%)
Ig strand C 164..169 CDD:409353 2/4 (50%)
Ig strand C' 172..174 CDD:409353 0/1 (0%)
Ig strand D 177..184 CDD:409353 0/6 (0%)
Ig strand E 191..199 CDD:409353 2/7 (29%)
Ig strand F 208..216 CDD:409353 3/7 (43%)
Ig strand G 222..228 CDD:409353 1/5 (20%)
Ig_3 234..303 CDD:404760 12/77 (16%)
Ig strand B 252..256 CDD:409353 0/3 (0%)
Ig strand C 266..270 CDD:409353 1/3 (33%)
Ig strand E 283..286 CDD:409353 0/2 (0%)
Ig strand F 292..301 CDD:409353 2/8 (25%)
Ig strand G 309..312 CDD:409353 1/2 (50%)
Ig 326..403 CDD:416386 22/113 (19%)
Ig strand A' 327..332 CDD:409353 0/10 (0%)
Ig strand B 335..344 CDD:409353 4/25 (16%)
Ig strand C 350..354 CDD:409353 2/15 (13%)
Ig strand C' 357..359 CDD:409353 0/1 (0%)
Ig strand D 362..365 CDD:409353 0/2 (0%)
Ig strand E 366..371 CDD:409353 2/6 (33%)
Ig strand F 379..387 CDD:409353 3/7 (43%)
Ig strand G 393..403 CDD:409353 3/9 (33%)
Ig 405..509 CDD:416386 19/114 (17%)
Ig strand A 406..410 CDD:409353 1/3 (33%)
Ig strand A' 412..415 CDD:409353 0/2 (0%)
Ig strand B 423..430 CDD:409353 1/9 (11%)
Ig strand C 437..442 CDD:409353 0/4 (0%)
Ig strand C' 444..447 CDD:409353 0/2 (0%)
Ig strand D 455..462 CDD:409353 1/7 (14%)
Ig strand E 472..479 CDD:409353 0/6 (0%)
Ig strand F 490..497 CDD:409353 2/6 (33%)
Ig strand G 500..507 CDD:409353 2/6 (33%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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