DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Fas2 and lsamp

DIOPT Version :9

Sequence 1:NP_001284854.1 Gene:Fas2 / 31364 FlyBaseID:FBgn0000635 Length:885 Species:Drosophila melanogaster
Sequence 2:XP_031751462.1 Gene:lsamp / 100124984 XenbaseID:XB-GENE-5759171 Length:368 Species:Xenopus tropicalis


Alignment Length:332 Identity:82/332 - (24%)
Similarity:133/332 - (40%) Gaps:44/332 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly   238 NLEAVEGKPFAANCTARGKPVPEISWIRDATQLNVATADRFQVNPQTGL---------VTISSVS 293
            |:...:|......|....:. ..::|: :.:.:..|..|::.::|:..|         :.|..|.
 Frog    40 NITVRQGDTAILRCFVEDRS-SRVAWL-NRSGIIFAGDDKWSLDPRVELEKRSLLEYSLRIQKVD 102

  Fly   294 QDDYGTYTCLAKNRAGVVDQKTKLNVLVRPQIYEL-YNVTGARTKEIAITCRAKGRPAPAITFRR 357
            ..|.|.|||..:.:......:..|.|.|.|:|..: .::|......:.:.|.|.|||.|.||:|.
 Frog   103 VSDEGPYTCSVQTKQHTKTTQVYLIV
QVPPKISNISADITVNEGSNVTLMCIAYGRPEPMITWRH 167

  Fly   358 WGTQEEYTNGQQDDDPRIILEPNFDEERGESTGTLRISNAERSDDGLYQCIARNKGADA-YKTGH 421
            .             .|.....|..|.|..|.  .|.|....|...|.|:|.|.|:.|.| .|...
 Frog   168 L-------------TPTAGTSPARDFEGEEE--FLEIQGITREQSGRYECKAANEVASADVKQVR 217

  Fly   422 ITVEFAPDFSHMKELPPVFSWEQRKANLSCLAMGIPNATIEWHWNGRKIKDLYDT-NLKIVGTGP 485
            :||.:.|..:..|.......   ::|.|.|.|..:|....||:.:..:.:.:... .|:|..||.
 Frog   218 VTV
NYPPIITESKSNEATTG---KQAILRCEASAVPAPDFEWYKDDTRSRRINSAQGLEIRNTGS 279

  Fly   486 RSDLIVHPVTRQYYSGYKCIATNIHGTAEHDMQLKEARVPDFVSEAKPSQLTATTMTFDIR---- 546
            ||.|:|..||.::|..|.|:|.|..|.....:.|.:.     ||..||  ::|:....::.    
 Frog   280 RSVLMVANVTEEHYGNYTCVAAN
KLGITNTSLYLYKR-----VSPTKP--MSASERGSNVHYQYK 337

  Fly   547 -GPSTEL 552
             ||.|.:
 Frog   338 VGPGTPI 344

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Fas2NP_001284854.1 IG_like 39..133 CDD:214653
IG_like 144..226 CDD:214653
IGc2 152..209 CDD:197706
I-set 230..319 CDD:254352 16/89 (18%)
IGc2 243..309 CDD:197706 14/74 (19%)
IG_like 330..424 CDD:214653 26/94 (28%)
IGc2 339..412 CDD:197706 21/72 (29%)
Ig 447..518 CDD:143165 23/71 (32%)
fn3 534..611 CDD:278470 4/24 (17%)
FN3 640..735 CDD:238020
lsampXP_031751462.1 Ig 38..128 CDD:416386 16/89 (18%)
FR1 38..54 CDD:409353 2/13 (15%)
Ig strand A' 39..45 CDD:409353 1/4 (25%)
Ig strand B 47..55 CDD:409353 1/7 (14%)
CDR1 55..59 CDD:409353 0/3 (0%)
FR2 60..67 CDD:409353 1/7 (14%)
Ig strand C 60..66 CDD:409353 1/6 (17%)
CDR2 68..78 CDD:409353 2/9 (22%)
Ig strand C' 70..73 CDD:409353 0/2 (0%)
Ig strand C' 75..78 CDD:409353 1/2 (50%)
FR3 79..114 CDD:409353 9/34 (26%)
Ig strand D 83..90 CDD:409353 1/6 (17%)
Ig strand E 93..99 CDD:409353 0/5 (0%)
Ig strand F 106..114 CDD:409353 4/7 (57%)
CDR3 115..119 CDD:409353 0/3 (0%)
Ig strand G 119..128 CDD:409353 1/8 (13%)
FR4 121..128 CDD:409353 1/6 (17%)
Ig_3 131..206 CDD:404760 24/89 (27%)
Ig strand A' 138..143 CDD:409353 0/4 (0%)
Ig strand B 149..156 CDD:409353 1/6 (17%)
Ig strand C 162..167 CDD:409353 2/4 (50%)
Ig strand C' 173..175 CDD:409353 0/1 (0%)
Ig strand E 185..191 CDD:409353 2/7 (29%)
Ig strand F 198..205 CDD:409353 3/6 (50%)
Ig strand G 212..220 CDD:409353 1/7 (14%)
Ig_3 223..302 CDD:404760 23/81 (28%)
putative Ig strand A 224..230 CDD:409353 1/5 (20%)
Ig strand B 240..244 CDD:409353 2/3 (67%)
Ig strand C 253..257 CDD:409353 1/3 (33%)
Ig strand E 281..285 CDD:409353 2/3 (67%)
Ig strand F 295..300 CDD:409353 2/4 (50%)
Ig strand G 308..311 CDD:409353 0/2 (0%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 58 1.000 Domainoid score I10621
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.000

Return to query results.
Submit another query.