Protein Alignment Tip60 and SAMD1

DIOPT Version :10

• Sequence 1: NP_572151.1
• Gene: Tip60 / 31362
• FlyBaseID: FBgn0026080
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_612361.1
• Gene: SAMD1 / 90378
• HGNCID: 17958
• Length: 538
• Species: Homo sapiens
• Alignment Length: 230
• Identity: 54/230 - (23%)
• Similarity: 70/230 - (30%)
• Gaps: 77/230 - (33%)

  Fly    80 KVQFPRRDGSQTGTSTGVTTPQRHHSLAGSVSRPTSPQ-HPGSGALAAIPQTPTGASGSVPPPAG 143
            :||.|||         |.|.|          :.|.:|: .|.:.|.||.|.||      .|||..
Human    98 RVQPPRR---------GATPP----------APPRAPRGAPAAAAAAAPPPTP------APPPPP 137

  Fly   144 IPNSVAPPG-----------TPSSGGELVNGNN------LAA---------ALQKRINRKRKNHG 182
            .|.:.|.|.           .|.|.|....|..      |||         |:......:|....
Human   138 APVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPP 202

  Fly   183 GSAHGHHSL------TSQQQQSHPHPTTPQTPTATPVHVTGDGLISGAAND----------DGDG 231
            ..|.....|      .:..||..|.|..||.|..     .|.....|||..          .|.|
Human   203 AVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPE-----GGAVRAGGAARPVSLREVVRYLGGSG 262

  Fly   232 SQDGKTPTPRQSGSMVTHQDDVVTRMKNVEMIELG 266
            ...|:....|..|.:   :::...|.: :|...||
Human   263 GAGGRLTRGRVQGLL---EEEAAARGR-LERTRLG 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tip60	NP_572151.1	CBD_TIP60_like	27..90	CDD:350848	5/9 (56%)
		PLN00104	<255..533	CDD:215056	4/12 (33%)
SAMD1	NP_612361.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..30
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	92..247		44/178 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	282..458		4/13 (31%)
		SAM_Atherin-like	459..527	CDD:188982