Protein Alignment Tip60 and ESA1

DIOPT Version :10

• Sequence 1: NP_572151.1
• Gene: Tip60 / 31362
• FlyBaseID: FBgn0026080
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_014887.3
• Gene: ESA1 / 854418
• SGDID: S000005770
• Length: 445
• Species: Saccharomyces cerevisiae
• Alignment Length: 542
• Identity: 209/542 - (38%)
• Similarity: 279/542 - (51%)
• Gaps: 132/542 - (24%)

  Fly     2 KINHKYEFDDDVASICESTAALTEGCRLPVRMHKTDDWPLAEIVSIKELDGRRQFYVHYVDFNKR 66
            |||..    ||:...|:..            :.|.|:..||||:||.......:||||||::|||
Yeast    14 KINSV----DDIIIKCQCW------------VQKNDEERLAEILSINTRKAPPKFYVHYVNYNKR 62

  Fly    67 LDEWVNEEDL-YTRKVQFP---------RRDGSQTGTSTGVTTPQRHHSLAGSVSRPTSPQHPGS 121
            ||||:..:.: ..::|.:|         ::...:..|:|. .|||  .||...|.
Yeast    63 LDEWITTDRINLDKEVLYPKLKATDEDNKKQKKKKATNTS-ETPQ--DSLQDGVD---------- 114

  Fly   122 GALAAIPQTPTGASGSVPPPAGIPNSVAPPGTPSSGGELVNGNNLAAALQKRINRKRKNHGGSAH 186
                                          |......::::.:||
Yeast   115 ------------------------------GFSRENTDVMDLDNL-------------------- 129

  Fly   187 GHHSLTSQQQQSHPHPTTPQTPTATPVHVTGDGLISGAANDDGDGSQDGKTPTPRQSGSMVTHQD 251
                                       :|.|        ..|.:.|.:.:....|.|||| |...
Yeast   130 ---------------------------NVQG--------IKDENISHEDEIKKLRTSGSM-TQNP 158

  Fly   252 DVVTRMKNVEMIELGRHRIKPWYFSPYPQELCQMPCIYICEFCLKYRKSRKCLERHLSKCNLRHP 316
            ..|.|::|:..|.:|::.|:||||||||.||.....|||.:|.|:|..|:|..||:..||.||||
Yeast   159 HEVARVRNLNRIIMGKYEIEPWYFSPYPIELTDEDFIYIDDFTLQYFGSKKQYERYRKKCTLRHP 223

  Fly   317 PGNEIYRKHTISFFEIDGRKNKVYAQNLCLLAKLFLDHKTLYYDTDPFLFYVMTEFDSRGFHIVG 381
            |||||||...:|||||||||.:.:.:|||||:||||||||||||.||||||.||..|..|.|:||
Yeast   224 PGNEIYRDDYVSFFEIDGRKQRTWCRNLCLLSKLFLDHKTLYYDVDPFLFYCMTRRDELGHHLVG 288

  Fly   382 YFSKEKESTEDYNVACILTMPPYQRKGYGKLLIEFSYELSKFEGKTGSPEKPLSDLGLLSYRSYW 446
            ||||||||.:.||||||||:|.|||.|||||||||||||||.|.|.||||||||||||||||:||
Yeast   289 YFSKEKESADGYNVACILTLPQYQRMGYGKLLIEFSYELSKKENKVGSPEKPLSDLGLLSYRAYW 353

  Fly   447 AQTILEIFISQNPSTDGEKPTITINDICECTSIKKEDVISTLQNLNLINYYKGQYIVCINRVIIE 511
            :.|::.:.:.       .:..|||::|...||:...|::.|.:.||::.|||||:|:.:|..|::
Yeast   354 SDTLITLLVE-------HQKEITIDEISSMTSMTTTDILHTAKTLNILRYYKGQHIIFLNEDILD 411

  Fly   512 QHRRAMDKRKIRIDSKCLHWTP 533
            ::.|...|::..||...|.|.|
Yeast   412 RYNRLKAKKRRTIDPNRLIWKP 433

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tip60	NP_572151.1	CBD_TIP60_like	27..90	CDD:350848	23/72 (32%)
		PLN00104	<255..533	CDD:215056	157/277 (57%)
ESA1	NP_014887.3	SAS2	16..431	CDD:227360	205/536 (38%)