DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tip60 and Samd1

DIOPT Version :9

Sequence 1:	NP_001259234.1	Gene:	Tip60 / 31362	FlyBaseID:	FBgn0026080	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	NP_001074884.1	Gene:	Samd1 / 666704	MGIID:	2142433	Length:	519	Species:	Mus musculus

Alignment Length:	183	Identity:	41/183 - (22%)
Similarity:	51/183 - (27%)	Gaps:	72/183 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 KVQFPRRDGSQTGTSTGVTTPQRHHSLAGSVSRPTSPQHPGSGALAAIPQTPTGASGSVPPPAG- 143
            :||.|||         |.|.|.......|..:.|.....|....:||..:.|..|:.:.||..|
Mouse    98 RVQPPRR---------GATPPAPPRVPRGGPAAPPPTPAPPPAPVAAPTRAPRAAAATAPPSPGP 153

  Fly   144 ---------------------IPNSVAPPGTPSSGGELVNGNNLAAALQKRINRKRKNHGGSAHG 187
                                 .|.:.|||..|                      :|......|..
Mouse   154 AQPGPRAQRAAPLAAPPPAPAAPPAAAPPAGP----------------------RRAPPPAVAAR 196

  Fly   188 HHSLTSQQQQSHPHPTTPQTP----------TATPV-------HVTGDGLISG 223
            ......||||  |.|..||.|          .|.||       ::.|.|..||
Mouse   197 EPPAPPQQQQ--PPPPQPQPPPEGGAARAGGPARPVSLREVVRYLGGSGGASG 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tip60	NP_001259234.1	Tudor-knot	23..78	CDD:288553
		Drf_FH1	84..>157	CDD:283903	21/94 (22%)
		PHA01732	139..>196	CDD:222828	11/78 (14%)
		NAT_SF	254..533	CDD:302625
		MOZ_SAS	316..500	CDD:280097
Samd1	NP_001074884.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..30
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	87..232		37/166 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	261..381
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	417..439
		SAM_Atherin-like	440..508	CDD:188982
		SAM	440..506	CDD:197735
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5027
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900