Protein Alignment Tip60 and kat8

DIOPT Version :10

• Sequence 1: NP_572151.1
• Gene: Tip60 / 31362
• FlyBaseID: FBgn0026080
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_001016234.2
• Gene: kat8 / 548988
• XenbaseID: XB-GENE-969438
• Length: 465
• Species: Xenopus tropicalis
• Alignment Length: 518
• Identity: 191/518 - (36%)
• Similarity: 267/518 - (51%)
• Gaps: 144/518 - (27%)

  Fly    27 CRLPVRMHKTDD-WPLAEIVS--IKELDGRRQFYVHYVDFNKRLDEWVNEEDLYTRKVQFPRRDG 88
            ||      :.|: |..||::.  :.|.:||.::|||||..|:||||||::..|...|..   :|.
 Frog    70 CR------RADNTWHSAEVIQSRLNEQEGREEYYVHYVGCNRRLDEWVDKNRLALTKTV---KDA 125

  Fly    89 SQTGTSTGVTTPQRHHSLAGSVSRPTSPQHPGSGALAAIPQTPTGASGSVPPPAGIPNSVAPPGT 153
            .|..|...:
 Frog   126 VQKNTDQYL-------------------------------------------------------- 134

  Fly   154 PSSGGELVNGNNLAAALQKRI--NRKRK----NHGGSAHGHHSLTSQQQQSHPHPTTPQTPTATP 212
                      |.|:...:::|  |:|||    ||           .|:..:...|||
 Frog   135 ----------NELSEQPERKITRNQKRKHDEINH-----------VQKTYAEMDPTT-------- 170

  Fly   213 VHVTGDGLISGAANDDGDGSQDGKTPTPRQSGSMVTHQDDVVTRMKNVEMIELGRHRIKPWYFSP 277
                                            :.:..:.:.:|::|.|:.|.:|.:.|..|||||
 Frog   171 --------------------------------AALEKEHEAITKIKYVDKIHIGNYEIDAWYFSP 203

  Fly   278 YPQELCQMPCIYICEFCLKYRKSRKCLERHLSKCNLRHPPGNEIYRKHTISFFEIDGRKNKVYAQ 342
            :|::..:.|.:::||:||||.|..|....||..|..|.|||.|||||..||.:|:||:.:|:|.|
 Frog   204 FPEDYGKQPKLWVCEYCLKYMKFEKSYRYHLGLCQWRQPPGKEIYRKGNISVYEVDGKDHKIYCQ 268

  Fly   343 NLCLLAKLFLDHKTLYYDTDPFLFYVMTEFDSRGFHIVGYFSKEKESTEDYNVACILTMPPYQRK 407
            ||||||||||||||||:|.:||:||::||.|.:|.||||||||||||.:..|||||||:|||||:
 Frog   269 NLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGAHIVGYFSKEKESPDGNNVACILTLPPYQRR 333

  Fly   408 GYGKLLIEFSYELSKFEGKTGSPEKPLSDLGLLSYRSYWAQTILEIFISQNPSTDGEKPTITIND 472
            ||||.||.|||||||.|...|||||||||||.|||||||:..:|||.       ...:.|::|.|
 Frog   334 GYGKFLIAFSYELSKLENTVGSPEKPLSDLGKLSYRSYWSWVLLEIL-------RDFRGTLSIKD 391

  Fly   473 ICECTSIKKEDVISTLQNLNLINYYKGQYIVCINRVIIEQHRRAMDKRK--IRIDSKCLHWTP 533
            :.:.|||.:.|:|.|||:||::.|:|||:::|:...::|:|.::...:|  |.:||..|.|.|
 Frog   392 LSQMTSITQNDIIGTLQSLNMVKYWKGQHVICVTPKLVEEHLKSAQYKKPPITVDSINLKWAP 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tip60	NP_572151.1	CBD_TIP60_like	27..90	CDD:350848	24/65 (37%)
		PLN00104	<255..533	CDD:215056	151/279 (54%)
kat8	NP_001016234.2	PLN00104	63..456	CDD:215056	191/518 (37%)