Protein Alignment Tip60 and kat7

DIOPT Version :9

• Sequence 1: NP_001259234.1
• Gene: Tip60 / 31362
• FlyBaseID: FBgn0026080
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: XP_012827190.1
• Gene: kat7 / 548673
• XenbaseID: XB-GENE-488776
• Length: 617
• Species: Xenopus tropicalis
• Alignment Length: 631
• Identity: 214/631 - (33%)
• Similarity: 305/631 - (48%)
• Gaps: 168/631 - (26%)

  Fly    14 ASICESTAALTEGCRLPVRMHKTDDWPLAEIVSIKELDGRRQFYVHYVDFNKRLDEWVNEEDLY- 77
            |.:..|||.|::..:        |..|:..:.|...                       ||.:|
 Frog    40 ARVTRSTARLSQSSQ--------DSSPVGNLQSFGA-----------------------EEPVYS 73

  Fly    78 TRKV-------------QFPRRDGSQTGTST--GVTTPQRHHSLAGSVSRPTSPQHPGSGALAAI 127
            ||:|             ::|.|....:|:.|  .|....|....||  ....||
 Frog    74 TRRVTRSQQQPTPVTPKKYPLRQTRSSGSETEQAVDFCDRDPKNAG--YHDESP----------- 125

  Fly   128 PQTPTGASGSVPPPAGI--PN-----SVAPPGTPSSGGELVNGNNLAAALQKR-------INRKR 178
            |:||||.:.|......|  ||     |:|...:...     :|::|:...::|       .|.|.
 Frog   126 PRTPTGNAPSSESDIDISSPNVSHDESIAKDMSLKD-----SGSDLSHRPKRRRFHESYNFNMKC 185

  Fly   179 KNHGGSAHGH-----------------HSLTS---------------------------QQQQSH 199
            ...|.::.||                 |:|::                           :|.:::
 Frog   186 PTPGCNSLGHLTGKHERHFSISGCPLYHNLSADECKNCDEFQVRAQSRDKQVEDRMLSHRQDENN 250

  Fly   200 PHPTTPQTPTATPVH----VT------GDGLISGAANDDGDGSQD-GKTPTP------------- 240
            .|.|..|.||...:.    ||      ..||.........:..|. |.|..|
 Frog   251 RHATRHQAPTERQLRYKEKVTELRKKRNSGLTKEQKEKYMEHRQTYGDTREPLLENLTSEYDLEL 315

  Fly   241 -RQSGSMVTHQDDV--------VTRMKN-VEMIELGRHRIKPWYFSPYPQELCQMPCIYICEFCL 295
             |::.:..:  ||:        :|...| ::.|..||:.:..||.||||:|..::..:|:|||||
 Frog   316 FRRAQARAS--DDLEKLRLQGQITEGSNMIKTIIFGRYELDTWYHSPYPEEYARLGRLYMCEFCL 378

  Fly   296 KYRKSRKCLERHLSKCNLRHPPGNEIYRKHTISFFEIDGRKNKVYAQNLCLLAKLFLDHKTLYYD 360
            ||.||:..|.||::||..:||||:|||||.:||.||:||:|||:|.|||||||||||||||||||
 Frog   379 KYMKSQTILRRHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYD 443

  Fly   361 TDPFLFYVMTEFDSRGFHIVGYFSKEKESTEDYNVACILTMPPYQRKGYGKLLIEFSYELSKFEG 425
            .:|||||||||.|:.|.|::|||||||.|..:|||:||||||.|.|:||||:||:|||.|||.|.
 Frog   444 VEPFLFYVMTEGDNTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVED 508

  Fly   426 KTGSPEKPLSDLGLLSYRSYWAQTILEIFISQNPSTDGEKPTITINDICECTSIKKEDVISTLQN 490
            |.||||:|||||||:||||||.:.:|...    .:..|::  |:|.:|.:.|::...|::||||.
 Frog   509 KVGSPERPLSDLGLISYRSYWKEVLLRYL----HNFQGKE--ISIKEISQETAVNPVDIVSTLQA 567

  Fly   491 LNLINYYKGQYIVCINRVIIEQHRRAMDKR---KIRIDSKCLHWTP 533
            |.::.|:||:::|...:.:|::......||   ...:|..||.|||
 Frog   568 LQMLKYWKGKHLVLKRQDLIDEWASKDAKRTNSNKTMDPSCLKWTP 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tip60	NP_001259234.1	Tudor-knot	23..78	CDD:288553	7/55 (13%)
		Drf_FH1	84..>157	CDD:283903	21/81 (26%)
		PHA01732	139..>196	CDD:222828	15/114 (13%)
		NAT_SF	254..533	CDD:302625	150/282 (53%)
		MOZ_SAS	316..500	CDD:280097	113/183 (62%)
kat7	XP_012827190.1	zf-C2HC	184..212	CDD:366692	4/27 (15%)
		PLN00104	<323..615	CDD:215056	154/299 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D285390at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010