Protein Alignment Tip60 and Kat6b

DIOPT Version :9

• Sequence 1: NP_001259234.1
• Gene: Tip60 / 31362
• FlyBaseID: FBgn0026080
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: XP_006519326.1
• Gene: Kat6b / 54169
• MGIID: 1858746
• Length: 2054
• Species: Mus musculus
• Alignment Length: 584
• Identity: 199/584 - (34%)
• Similarity: 279/584 - (47%)
• Gaps: 130/584 - (22%)

  Fly    50 LDGRRQFYVHYVDFNKRLDEWVNEEDLYTRKVQFPRRDGSQTGTSTGVTTPQRHHSLAGSVSRPT 114
            :||..:|:....|..:...|.::....|.     ||:..||..:.|.       |.||...::..
Mouse   436 IDGLTKFFTPSPDGRRSRGEIIDFSKHYR-----PRKKVSQKQSCTS-------HVLATGTTQKL 488

  Fly   115 SPQHPGSGALAAIPQTP-TGASGSVPPPAGIPNSVAPPGTPSSGGE-----LVNGNNLAA----- 168
            .|     ...|.:|..| :|.|.|....:...:|.:...:.|..||     |.|.:.|.|
Mouse   489 KP-----APSALLPPAPISGQSPSSQKSSSSTSSTSTQSSSSQSGEPSFSSLTNNSQLKALFDGL 548

  Fly   169 ------------------ALQKRINRKRK----------------------NHG----GSAHGH- 188
                              |..||:.||.:                      :|.    |...||
Mouse   549 SHIYTTQGQSRKKGHPSYAPPKRMRRKTEFSSTAKAKARFFGKRDFRSRLLSHSSCSWGMTRGHI 613

  Fly   189 -----HSLTSQQQQSH------PHPTTPQTPTATPVHVTGDG-LISGAANDDGDGSQDGKTPTPR 241
                 |...:...:.|      .:..|||..|.:    :|.| |..|..|.|.|...|.|....:
Mouse   614 FKAIAHFKRTTFLKKHRMLGRLKYKVTPQMGTPS----SGKGSLADGRINPDQDNDTDIKISIKQ 674

  Fly   242 QSG--------SMVTHQD-DVVTRMKNV------------------EMIELGRHRIKPWYFSPYP 279
            :|.        .:||.:| ||..:.:.:                  .:||.|::.|:.||.||||
Mouse   675 ESADVSLVGNKELVTEEDLDVFKQAQELSWEKIECESGVEDCGRYPSVIEFGKYEIQTWYSSPYP 739

  Fly   280 QELCQMPCIYICEFCLKYRKSRKCLERHLSKCNLRHPPGNEIYRKHTISFFEIDGRKNKVYAQNL 344
            ||..::|.:|:|||||||.||:..|.||..||...|||.|||||:..:|.||:||..:|:|.|||
Mouse   740 QEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNL 804

  Fly   345 CLLAKLFLDHKTLYYDTDPFLFYVMTEFDSRGFHIVGYFSKEKESTEDYNVACILTMPPYQRKGY 409
            ||||||||||||||||.:||||||:|:.|.:|.|:||||||||...:.|||:||:.||.:||:|:
Mouse   805 CLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGF 869

  Fly   410 GKLLIEFSYELSKFEGKTGSPEKPLSDLGLLSYRSYWAQTILEIFISQNPSTDGEKPTITINDIC 474
            |:.||:|||.||:.||:.|||||||||||.|||.:||...|||.....:      :..|:|..|.
Mouse   870 GRFLIDFSYLLSRREGQAGSPEKPLSDLGRLSYLAYWKSVILEYLYRHH------ERHISIKAIS 928

  Fly   475 ECTSIKKEDVISTLQNLNLINYYKGQYIVCINRVIIEQHRRAMDK-----RKIRIDSKCLHWTP 533
            ..|.:...|:.:|||:|::|:...|::::.....:|..|   |:|     |...:|.:.|.|||
Mouse   929 RATGMCPHDIATTLQHLHMIDRRDGRFVIIRREKLILGH---MEKLKNCSRPNELDPESLRWTP 989

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tip60	NP_001259234.1	Tudor-knot	23..78	CDD:288553	5/27 (19%)
		Drf_FH1	84..>157	CDD:283903	17/73 (23%)
		PHA01732	139..>196	CDD:222828	18/116 (16%)
		NAT_SF	254..533	CDD:302625	138/301 (46%)
		MOZ_SAS	316..500	CDD:280097	100/183 (55%)
Kat6b	XP_006519326.1	H15	94..168	CDD:197772
		PHD1_MOZ_MORF	213..270	CDD:277090
		PHD2_KAT6A_6B	272..318	CDD:277002
		PLN00104	<721..989	CDD:215056	138/276 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5027
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D629545at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820