Protein Alignment Tip60 and kat5b

DIOPT Version :10

• Sequence 1: NP_572151.1
• Gene: Tip60 / 31362
• FlyBaseID: FBgn0026080
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: XP_021331810.1
• Gene: kat5b / 503731
• ZFINID: ZDB-GENE-030131-985
• Length: 555
• Species: Danio rerio
• Alignment Length: 587
• Identity: 314/587 - (53%)
• Similarity: 380/587 - (64%)
• Gaps: 94/587 - (16%)

  Fly    16 ICESTAALTEGCRLPV---RMHKTDDWPLAEIVSIKELDGRRQFYVHYVDFNKRLDEWVNEEDLY 77
            :.|.|..:.|||||||   .....|:||||||:|:|::.||:.:||||:||||||||||..:.|.
Zfish     1 MAEPTVEIVEGCRLPVLRKNQENEDEWPLAEILSVKDIPGRKLYYVHYIDFNKRLDEWVTPDRLD 65

  Fly    78 TRKVQFPRRDGSQTGTSTGVTTPQRHHSLAGSVSRPTSPQHPGSGAL------AAIPQ------T 130
            .:|:|||::: ::|.|..|         |.|  |||:||:.....:|      |:.|.      |
Zfish    66 LKKLQFPKKE-AKTPTKNG---------LPG--SRPSSPEREVRKSLDLNVQSASAPSRGKTLPT 118

  Fly   131 PTGASGSVPPPAGIPNSVAPPGTPSSG---------------------------GELVNGNNLAA 168
            |...:.||.....:..:...|..|||.                           ..|........
Zfish   119 PKRKAESVSLATQVTAATPVPSLPSSAEASQASVYPAMRDSSFSIKAREEHEQLTSLTTNGTTRR 183

  Fly   169 ALQKRINRKRKNHGGSAHGHHSLTSQQQQSHPHPTTPQTPTATPVHVTGDGLISGAANDDGDGSQ 233
            .:..:..|||||    ..|...:....|.:.|..:|...|                ..:|...|.
Zfish   184 LIPSQPGRKRKN----CVGTEEIVKVFQNNSPRSSTVYLP----------------PGEDSQDSS 228

  Fly   234 DGKTPTPRQSGSMVTHQ--DDVVTRMKNVEMIELGRHRIKPWYFSPYPQELCQMPCIYICEFCLK 296
            ||....||.:||:|:.:  ||::|||||::.|||||||:||||||||||||..:|.:|:||||||
Zfish   229 DGIPSAPRMTGSLVSDRSHDDIITRMKNIDCIELGRHRLKPWYFSPYPQELTTLPILYLCEFCLK 293

  Fly   297 YRKSRKCLERHL-----------------SKCNLRHPPGNEIYRKHTISFFEIDGRKNKVYAQNL 344
            |.||.|||:|||                 :|||||||||||||||.|||||||||||||:|:|||
Zfish   294 YLKSLKCLQRHLVRAVLGPDVTHSQHQIKTKCNLRHPPGNEIYRKGTISFFEIDGRKNKMYSQNL 358

  Fly   345 CLLAKLFLDHKTLYYDTDPFLFYVMTEFDSRGFHIVGYFSKEKESTEDYNVACILTMPPYQRKGY 409
            |||||.|||||||||||||||||||||:||:|||||||||||||||||||||||||:|||||:||
Zfish   359 CLLAKCFLDHKTLYYDTDPFLFYVMTEYDSKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGY 423

  Fly   410 GKLLIEFSYELSKFEGKTGSPEKPLSDLGLLSYRSYWAQTILEIFISQNPSTDGEKPTITINDIC 474
            |||||||||||||.|||||:|||||||||||||||||:||||||.::.. |.:||:|.:|||:|.
Zfish   424 GKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMNLK-SENGERPQMTINEIS 487

  Fly   475 ECTSIKKEDVISTLQNLNLINYYKGQYIVCINRVIIEQHRRAMDKRKIRIDSKCLHWTPKDWSKR 539
            |.||:||||||||||.||||||||||||:.::..|:|.|.|||.||.:||||||||:||||||||
Zfish   488 EITSVKKEDVISTLQYLNLINYYKGQYILTLSEDIVEGHERAMHKRHLRIDSKCLHFTPKDWSKR 552

  Fly   540 SK 541
            .|
Zfish   553 GK 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tip60	NP_572151.1	CBD_TIP60_like	27..90	CDD:350848	35/65 (54%)
		PLN00104	<255..533	CDD:215056	223/294 (76%)
kat5b	XP_021331810.1	CD_CSD	15..78	CDD:475127	32/63 (51%)
		PLN00104	<243..546	CDD:215056	225/303 (74%)