Protein Alignment Tip60 and kat5a

DIOPT Version :10

• Sequence 1: NP_572151.1
• Gene: Tip60 / 31362
• FlyBaseID: FBgn0026080
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_001002365.1
• Gene: kat5a / 436638
• ZFINID: ZDB-GENE-040718-57
• Length: 541
• Species: Danio rerio
• Alignment Length: 573
• Identity: 318/573 - (55%)
• Similarity: 383/573 - (66%)
• Gaps: 80/573 - (13%)

  Fly    16 ICESTAALTEGCRLPV---RMHKTDDWPLAEIVSIKELDGRRQFYVHYVDFNKRLDEWVNEEDLY 77
            :.:.:..:||||||||   .....|:||||||:|:|::.||:.:|||||||||||||||..:.|.
Zfish     1 MADHSVEITEGCRLPVLRRNQENEDEWPLAEILSVKDISGRKLYYVHYVDFNKRLDEWVTPDRLD 65

  Fly    78 TRKVQFPRRDGSQTGTSTGVTTPQRHHSLAGSVSRPTSPQHPGSGALAAIPQTPTGAS--GSVPP 140
            .:|:|||:::..         ||.: :.|:|  |||:||:.....:|....|:.:..|  .:||.
Zfish    66 IKKLQFPKKEAK---------TPMK-NGLSG--SRPSSPERDVKKSLDLHVQSASAPSRGKTVPT 118

  Fly   141 P--------------AGIPNSVAPPGTPSSGGELVNG---------------------NNLAAAL 170
            |              |..|....|..|.:|...|...                     .|...::
Zfish   119 PKRKAESVSLATQVTAATPVPSLPASTEASQAALYTAIRDASFNIKSREEHEPLTSLTTNGTTSI 183

  Fly   171 QKRI-----NRKRKNHGGSAHGHHSLTSQQQQSHPHPTTPQTPTATPVHVTGDGLISGAANDDGD 230
            |:.:     .|||||.||:    ..:....|.:.|..:|..             |:.|   :|..
Zfish   184 QRHLIPPQPGRKRKNCGGT----DEMVKVFQNNSPRCSTVY-------------LLPG---EDSQ 228

  Fly   231 GSQDGKTPTPRQSGSMVTHQ--DDVVTRMKNVEMIELGRHRIKPWYFSPYPQELCQMPCIYICEF 293
            .|.||....||.:||:|:.:  ||:||||||:..|||||||:||||||||||||..:|.||:|||
Zfish   229 DSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIGCIELGRHRLKPWYFSPYPQELTSLPIIYLCEF 293

  Fly   294 CLKYRKSRKCLERHLSKCNLRHPPGNEIYRKHTISFFEIDGRKNKVYAQNLCLLAKLFLDHKTLY 358
            ||||.||.|||:|||:|||||||||||||||.|||||||||||||.|:||||||||.||||||||
Zfish   294 CLKYLKSLKCLQRHLTKCNLRHPPGNEIYRKGTISFFEIDGRKNKAYSQNLCLLAKCFLDHKTLY 358

  Fly   359 YDTDPFLFYVMTEFDSRGFHIVGYFSKEKESTEDYNVACILTMPPYQRKGYGKLLIEFSYELSKF 423
            |||||||||||||:|.:|||||||||||||||||||||||||:|||||:|||||||||||||||.
Zfish   359 YDTDPFLFYVMTEYDPKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKV 423

  Fly   424 EGKTGSPEKPLSDLGLLSYRSYWAQTILEIFISQNPSTDGEKPTITINDICECTSIKKEDVISTL 488
            |||||:|||||||||||||||||:||||||.:... |.:||:|.||||:|.|.||||||||||||
Zfish   424 EGKTGTPEKPLSDLGLLSYRSYWSQTILEILMDLK-SENGERPQITINEISEITSIKKEDVISTL 487

  Fly   489 QNLNLINYYKGQYIVCINRVIIEQHRRAMDKRKIRIDSKCLHWTPKDWSKRSK 541
            |.||||||||||||:.::..|:|.|..||.||.:|||.||||:||||||||.|
Zfish   488 QYLNLINYYKGQYILTLSEDIVEGHECAMQKRHLRIDPKCLHFTPKDWSKRGK 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tip60	NP_572151.1	CBD_TIP60_like	27..90	CDD:350848	36/65 (55%)
		PLN00104	<255..533	CDD:215056	223/277 (81%)
kat5a	NP_001002365.1	CBD_TIP60_like	15..78	CDD:350848	33/71 (46%)
		PLN00104	<246..532	CDD:215056	226/286 (79%)