Protein Alignment Tip60 and enok

DIOPT Version :10

• Sequence 1: NP_572151.1
• Gene: Tip60 / 31362
• FlyBaseID: FBgn0026080
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_523838.1
• Gene: enok / 37859
• FlyBaseID: FBgn0034975
• Length: 2291
• Species: Drosophila melanogaster
• Alignment Length: 548
• Identity: 183/548 - (33%)
• Similarity: 261/548 - (47%)
• Gaps: 103/548 - (18%)

  Fly    68 DEWVNEEDLYTRKVQFPRRDGSQTG--------TSTGVTTPQRHH------SLAGSVSRP----T 114
            ||:..|||..|.:.....::..::|        |..|:.:||.:.      ..|.....|    .
  Fly   462 DEYDEEEDYDTDRSTIREKNVFESGKQSCAKLSTGDGLGSPQNNELGSENWGFAAVAKNPIDIFV 526

  Fly   115 SPQH-----------PGSGALAAIP-----QTPTGASGSVPPPAGIP---------------NSV 148
            ..:|           |.:...|..|     |..|..:.|.|.....|               ..:
  Fly   527 KSKHNSNVKGIGYSKPAASTFATSPAANRVQKSTPVASSTPEKNSAPIGGMTIKRQTANGQKKKI 591

  Fly   149 AP-PGTPSSGGE-----------LVNGNNLAAALQKRINRKRKNHGGSAHGHHSLTSQQ------ 195
            .| ...|...|:           |.....:...|.:.|.|.|:.| ..|.|...:.:.:
  Fly   592 VPLKSMPLEAGKSYEKCEDDIPYLTEETVMKVQLLEEIERSRETH-SQADGKREMNNDEDAPGES 655

  Fly   196 -QQSHPHPTTPQTP--TATPVHVTGDGLISGAANDDGDGSQDGKTPTPRQSGSMVTHQDDVVTR- 256
             ::::|....|..|  |||.|.:..:.|.....               :.|.:.:...:||..:
  Fly   656 TKRANPFENQPLPPGVTATDVELYQEVLHKAVV---------------QMSNNHIEKVNDVSLKS 705

  Fly   257 ---MKNVEMIELGRHRIKPWYFSPYPQELCQMPCIYICEFCLKYRKSRKCLERHLSKCNLRHPPG 318
               .::.:.|::|:..|:.||.||:|||..::..:::|||||||.|||..|:||.:||..:.|||
  Fly   706 GQNTQSPKSIQIGKWDIETWYSSPFPQEYARLLKLFLCEFCLKYTKSRSVLDRHQNKCIWKQPPG 770

  Fly   319 NEIYRKHTISFFEIDGRKNKVYAQNLCLLAKLFLDHKTLYYDTDPFLFYVMTEFDSRGFHIVGYF 383
            .||:|:..||.||:||..||:|.||||||||.||||||||||.:|||||::|:.|..|.|:||||
  Fly   771 TEIFRQGNISVFEVDGNVNKIYCQNLCLLAKFFLDHKTLYYDVEPFLFYILTKNDQSGCHLVGYF 835

  Fly   384 SKEKESTEDYNVACILTMPPYQRKGYGKLLIEFSYELSKFEGKTGSPEKPLSDLGLLSYRSYWAQ 448
            ||||..|:.|||:||||||.|||:|||:.||:|||.||:.||:.|:|||||||||.|||.|||..
  Fly   836 SKEKHCTQKYNVSCILTMPQYQRQGYGRFLIDFSYLLSREEGQLGTPEKPLSDLGRLSYFSYWKS 900

  Fly   449 TILEIFISQNPSTDGEKPTITINDICECTSIKKEDVISTLQNLNLINYYKG----QYIVCI---- 505
            .:||........|     .||..||...|.:...|:....:.||.|...|.    :|.:.:
  Fly   901 VVLEYLYKHRNYT-----KITFKDIAIKTGLAISDIALAFELLNFIKLRKNDGDIRYQINVKIEW 960

  Fly   506 NRVIIEQHRRAMDKRKIRIDSKCLHWTP 533
            .:|:...::.|..|.:|.|:..||.|:|
  Fly   961 KKVLAHHNKMANSKTRIIIEPDCLRWSP 988

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tip60	NP_572151.1	CBD_TIP60_like	27..90	CDD:350848	6/21 (29%)
		PLN00104	<255..533	CDD:215056	138/289 (48%)
enok	NP_523838.1	PHD_SF	183..>215	CDD:473978
		PHD	248..292	CDD:214584
		PLN00104	<714..989	CDD:215056	139/280 (50%)
		PspC_subgroup_1	<1171..>1440	CDD:468201
		PRK10263	<1206..>1736	CDD:236669